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41 articles for “Minimum Inhibitory Concentration”
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Research ArticleOpen accessIn the keywordsFrequency of Carbapenem Resistance among Gram Negative Pathogens in a Tertiary Care Hospital in Southern PakistanWaseela Ashraf, Altaf AhmedCarbapenems are considered the treatment of choice for treating the multi-drug resistance Gram negative bacteria. But resistance to these antibiotics has increased worldwide thus limiting therapeutic options for clinicians. To investigate the frequency and Minimum Inhibitory Concentrations (MICs) of carbapenem resistance in Gram negative organisms at a tertiary care hospital in Southern Pakistan. Seven Hundred and ninety-three carbapenem resistant isolates … …American Journal of Infectious Diseases, Vol. 11, Issue 4 · 29 Oct 2015 · 7,573 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEVALUATION OF ANTIMICROBIAL ACTIVITY IN OLIVE (OLEA EUROPAEA) LEAF EXTRACTMukadderat Gökmen, Recep Kara, Levent Akkaya et al.In this study the antimicrobial activity of Olive Leaf Extracts (OLE) was screened against five gram-positive and five gram-negative bacteria. The antimicrobial activity was evaluated using disc diffusion and microdilution methods. The diameters of inhibition zones of the olive leaf extract were observed 13.33±2.08 mm against S. typhimurium and 21.67±1.53 mm against B. cereus. There was a similarity between the … …Current Research in Microbiology, Vol. 5, Issue 2 · 15 Jan 2015 · 15,214 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAntibacterial Activity of β-Cyclodextrin and 2-Hydroxypropyl-β-Cyclodextrin Trimethoprim ComplexesHsien-Kuo Sun, Madhumathi Seshadri, Scott Lingard et al.Problem statement: Cyclodextrin complexation has previously been shown to improve the solubility and dissolution properties of trimethoprim; however, no report provides an account of the effect cyclodextrin complexation has on the antibacterial activity of this agent. Approach: β-cyclodextrin and 2-hydroxypropyl β-cyclodextrin inclusion complexes of trimethoprim were prepared and confirmed by differential scanning calorimetry and proton nuclear magnetic resonance. The in-vitro … …Current Research in Microbiology, Vol. 2, Issue 1 · 26 Oct 2011 · 14,801 accessesView PDFCite
Research ArticleOpen accessIn the keywordsComparison of Diagnostic Tests for Fosfomycin Resistance Detection in Clinically Significant EnterobacteralesSantoshi Maruti Naik, Biranthabail Dhanashree, Himani KotianMultidrug resistance in Enterobacterales has triggered interest in old antibiotics like fosfomycin. Various methods to determine fosfomycin resistance are time-consuming and yield unpredictable results. Hence, the study was undertaken to compare the rapid fosfomycin NP test with the recommended agar dilution test and few other tests. In this cross-sectional, time-bound, prospective study, Enterobacterales (N = 110) were tested for their … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 21 Nov 2025 · 2,113 accessesView PDFCite
Research ArticleOpen accessIn the abstractCytocompatibility and Antimicrobial Properties of Silver Nanoparticles-Loaded AMPs in the Oral CavityYanli Lv, Weikai ZhangPostoperative infection following oral metal implantation is a key factor that affects the success rate of surgery. This infection is mainly caused by bacterial biofilms. Traditional single antibacterial coatings have limitations, including a narrow antibacterial spectrum and poor cytotoxicity or stability. This study combined silver nanoparticles (AgNPs) and the synthetic antimicrobial peptide GL13K using electrostatic self-assembly technology to create a … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 24 Apr 2026 · 1,685 accessesView PDFCite
Research ArticleOpen accessIn the abstractEnhanced Antibacterial Activity of Blended Essential Oils against Staphylococcus Aureus and Methicillin-Resistant Staphylococcus AureusMin-Gi Kwon, Ji-Hyuk Kang, Jae Kyung KimWe aimed to evaluate the antibacterial effects of four blended and four single essential oils on the gram-positive bacterium Staphylococcus aureus (S. aureus) and methicillin-resistant S. aureus (MRSA). Minimum inhibitory concentration (MIC) testing was performed using disk diffusion and broth microdilution methods according to the Clinical and Laboratory Standards Institute criteria. The blended essential oils exhibited more powerful antibacterial activity … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 16 Apr 2026 · 1,594 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimization of Hydrodistillation Extraction by Response Surface Methodology and Evaluation of the Antioxidant and Antimicrobial Activities of Essential Oils from Phragmites communis (Cav) TrinXin-Tong Zou, Hong-Yuan Ma, Yu-He Li et al.The principal objectives of this study encompass three distinct aspects: firstly, to streamline the extraction process of Phragmites communis (Cav) Trin essential oil; secondly, to systematically analyze the essential oil’s chemical composition; and finally, to evaluate biological activity. Through the system optimization experiment, the optimal extraction process was determined: the crushing size was set to 10 mesh, the total solid-liquid … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 6 Jan 2026 · 2,315 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibacterial Activity of Tali Bamboo (Gigantochloa apus) Leaf Extract to Inhibit Escherichia coli and Salmonella typhimuriumSinta Agustina, Komang Gede Wiryawan, Sri SuhartiBamboo leaves contain phytochemical compounds that have the potential to act as antimicrobial agents in inhibiting pathogenic bacteria. This study aimed to evaluate the potential of tali bamboo (Gigantochloa apus) leaves extracted with different solvents to inhibit the growth of Escherichia coli and Salmonella typhimurium. The tali bamboo leaves were extracted using ethanol and methanol with a ratio of 1:10 … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 3 · 25 Nov 2025 · 2,919 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Evaluation of Synergistic Antibacterial Effects in Blended Essential Oil against Gram-Positive and Gram-Negative PathogensMin-Gi Kwon, Jae Kyung KimThe rising emergence of multidrug-resistant bacteria has heightened the search for novel antibiotic agents. Essential Oils (EOs) are complex combinations of volatile organic compounds generated by plants, with many exhibiting significant antimicrobial properties. This study evaluates the antibacterial movement of single and blended EOs against representative gram-positive bacteria Staphylococcus aureus and Methicillin-Resistant S. aureus (MRSA) and gram-negative bacteria Escherichia coli … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 7 Jul 2025 · 5,481 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntioxidant and Antibacterial Properties of Essential Oils from Citrus reticulata cv. Shatangju Peel for the Preservation of Chilled PorkYao Dong, Xintong Zou, Hongli Zhou et al.Citrus reticulata cv. Shatangju peel essential oil (CrspEo), with three major components D-limonene (88.15%), γ-terpinene (4.59%) and β-myrcene (2.62%), possessed antioxidant activities with DPPH and ABTS+ radical scavenging with the IC50 (concentration of CrspEo scavenging 50% of radical) of 9.87±0.12% and 0.48±0.02%, respectively. Meanwhile, CrspEo showed antimicrobial activity in suppressing the growth of Bacillus pumilus, Bacillus subtilis, Candida albicans, Escherichia … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 3 · 31 Jul 2024 · 4,748 accessesView PDFCite