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6 results for “Metformin”
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Research ArticleOpen accessEvery word in the titleEffect of Metformin Treatment on Inflammatory Factors and Gut Microbial Diversity in Patients with Type II Diabetes MellitusLei Tong, Jingjing Zhang, Li Xiao Yue et al.With the persistent rise in the prevalence of Type 2 Diabetes Mellitus (T2DM), traditional treatment evaluations have primarily focused on glycemic control, often overlooking the multidimensional effects of medications. As a first-line therapeutic agent, the anti-inflammatory effects and gut microbiota regulation mechanisms of metformin remain incompletely elucidated. This prospective cohort study established a metformin treatment group and a T2DM control … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 20 Jul 2026 · 774 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBiochemical Efficacy of Nigella Sativa Oil and Metformin on Induced Diabetic Male RatsYassmina K. Mahmoud, Sherif Y. Saleh, Abd El Rehim A. El Ghannam, Ibrahim A. IbrahimThis study was carried out to investigate possible beneficial effects of Nigella sativa oil supplementation to diabetic rats. Fifty male Sprague-Dawley rats were randomly divided into five groups (n = 10/group) as follows: group I (normal control), group II (diabetic control), group III (diabetic rats treated with metformin), group IV (diabetic rats treated with metformin and Nigella sativa oil) and … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 24 Dec 2014 · 7,898 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAdiponectin Regulation in Type 2 Diabetic Rats: Effects of Insulin, Metformin and DexamethasoneTamer Ahmed Ismail, Mohamed Mohamed Soliman, Shimaa Ahmed IsmailAdiponectin is a protein synthesized from adipose tissue, increases peripheral glucose utilization in liver and skeletal muscle. Adiponectin expression and secretion are decreased during obesity and insulin resistance. In this study, the effect of insulin, metformin and dexamethasone on serum lipid profiles was examined in Type 2 Diabetic (T2D) rats. T2D was induced by feeding rats a high fat diet … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 23 Nov 2013 · 7,723 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleInteraction of Momordica charantia with Metformin in Diabetic RatsTripathi Poonam, Gupta Prem Prakash, Lal Vijay KumarNow a day’s people use herb or herbal remedies along with their medication in long term treatment of various disease. Concomitant use of herb and drug can interact with each other may cause herb drug interaction. The present study was designed to investigate the possible herb drug interaction between Momordica Chrantia Fruit Juice (MCFJ) and metformin. Metformin was given orally … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 3 · 4 Sep 2013 · 10,167 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Type 2 Anti-Diabetes on Bound Flavonoids of Barringtonia racemosa (L.) Spreng. Kernel in Glucose-Induced Diabetic RatsMusri Musman, Emelda Audina, Fazlia Inda Rahmayani Ratu et al.A study of type 2 anti-diabetes on bound flavonoids fraction from the kernel of Barringtonia racemosa (L.) Spreng. in glucose-induced diabetic rats was performed. This learning aimed to gather scientific information about the possibility to utilize kernel of B. racemosa as a raw material of antidiabetic drug. The antioxidant property of the bound flavonoids was determined by the DPPH scavenging … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 3 · 16 Dec 2017 · 8,040 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Diabetic Activity of a Fraction from Cissus verticillata and Tyramine, its Main Bioactive Constituent, in Alloxan-Induced Diabetic RatsCleide de Sousa Lino, Thiago de P. Sales, Patrícia B. Gomes et al.Cissus verticillata (syn. C. sycioides, fam. Vitaceae) is a medicinal plant popularly used in Brazil, for the treatment of diabetes mellitus. The anti-diabetic activity of a fraction from leaves of Cissus verticilllata (MSF, methanol soluble fraction), as well as that of tyramine (TYR) were investigated, in the model of alloxan-induced diabetes, in male Wistar rats. The biochemical parameters studied were: … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 4 · 31 Dec 2007 · 8,627 accessesView PDFCite