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11 articles for “Mediator Effect”

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Research ArticleOpen accessIn the keywordsThe Effect of National Culture on Total Quality Management and Organizational PerformanceRabiul Islam, Abdullah ALNasserSoft-hard total quality management comprises of the utility of human resource management-style personnel policies to product commitment to quality and a management ideology that supports cultural change maxims, continuous improvement and customer satisfaction. The aim of the study is to determine the mediator effect of national culture on the relationship between soft-hard total quality management and organizational performance in municipalities. … …American Journal of Applied Sciences, Vol. 10, Issue 10 · 5 Sep 2013 · 7,254 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Anti-Inflammatory Potential of Turmimax® an in vivo and in vitro StudyFiroz Hussain H M., Nanjundaiah S., Sadashiva Channangihalli Thimmegowda et al.The main objective of this study was to investigate the in vivo and in vitro anti-inflammatory effects of the Turmimax® bio-enhanced turmeric formulation. By comparing the relative fluorescence intensities of the interleukins IL-8 (Interleukin-8) and IL-12 (Interleukin-12) cytokines in stimulated murine Raw 264.7 macrophages, Turmimax® was evaluated for its anti-inflammatory in vitro efficacy. Turmimax® was administered orally in two doses, … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 24 Nov 2022 · 6,581 accessesView PDFCite
Research ArticleOpen accessIn the abstractManufacturing Strategy and Competitive Advantage: A Mediating role of Organizational Culture (A Case Study of Small Industry Batik Trusmi Indonesia)Aam Amaningsih Jumhur, Nik Hasnaa Nik Mahmood, MuchdieThe effect of manufacturing strategy and competitive advantage has empirically resulted varied studies with regards to industry or service sectors as object of the study. Manufacturing strategy on one side directly affects competitive advantage in addition to giving an effect to competitive advantage mediated by organizational culture variable on the other side. Regarding this condition, this study aims to investigate … …American Journal of Applied Sciences, Vol. 14, Issue 7 · 19 Jul 2017 · 8,032 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Pre-Slaughter Autophagic Status on Postmortem Proteolysis in Skeletal Muscle of MiceTomonori Nakanishi, Miho Yamashita, Naoto Nishimoto et al.Post mortem proteolysis is a key event during the aging process, where muscle converts to meat. However, its precise mechanism remains unclear. In this study, the effects of pre-slaughter autophagic status on post mortem proteolysis were investigated using mouse skeletal muscle. Mice were fasted for 14 h and administered with or without the autophagy inhibitor wortmannin, whereas control mice were … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 2 · 10 Jul 2017 · 7,988 accessesView PDFCite
HypothesisOpen accessIn the abstractCJ-023,423 (Grapiprant) a Potential Novel Active Compound with Antihyperalgetic Properties for Veterinary PatientsMario GiorgiCompanion animals are now living longer and so are more commonly manifesting age- and pain-related disease. Nonsteroidal anti-inflammatory drugs are the most used drug in osteoarthritis and inflammatory pain of various aetiologies. Despite their safety profiles have been amended from the COX-non selective to the COX-2 selective inhibitor class, some adverse effects are still of concern especially in long term … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 14 May 2015 · 8,874 accessesView PDFCite
Literature ReviewOpen accessIn the abstractImproving Organizational Citizenship Behavior through Spirituality and Work EngagementAminah Ahmad, Zoharah OmarThe focus of previous studies on predictors of organizational citizenship behavior has been on individual, organizational and task characteristics as well as leadership behaviors. Despite the greater focus of previous studies on individual characteristics, little is known about the potential effect of spirituality on organizational citizenship behavior. Using the work engagement model and results from previous empirical studies, a framework … …American Journal of Applied Sciences, Vol. 12, Issue 3 · 7 May 2015 · 7,139 accessesView PDFCite
Research ArticleOpen accessIn the abstractRADIOSENSITIZATION OF CANCER STEM CELLS: TARGETING TGFβ, NOTCH OR TELOMERASE TO IMPROVE TUMOR RESPONSE O RADIOTHERAPYIgnacio Fernandez-GarciaRadiation resistant cancer stem cells are the main reason for treatment failure and tumor recurrence after cancer radiotherapy. Increasing biological evidences demonstrate that these cells possess the capacity to repair radiation induced DNA damage, protect themselves from radiation derived reactive oxygen species, survive and proliferate after several fractions of radiotherapy and finally, repopulate the heterogeneity of the tumor. Thus, targeting … …Current Research in Medicine, Vol. 5, Issue 2 · 16 Jul 2014 · 7,459 accessesView PDFCite
Research ArticleOpen accessIn the abstractPalmitate-Induced Translocation of Caveolin-3 and Endothelial Nitric Oxide Synthase in CardiomyocytesCatherine J. Knowles, Megan Dionne, Martina Cebova, Ilka M. PinzProblem statement: Palmitate is a known cardiac lipotoxin that blunts cardiomyocyte contractile function and induces apoptosis, likely via accumulation of the lipotoxic ceramide. Ceramide is a sphingolipid and localizes to caveolae, which are lined in the inner membrane leaflet by caveolin proteins. In this study, we investigated the effects of palmitate on caveolin proteins and on endothelial Nitric Oxide Synthase … …OnLine Journal of Biological Sciences, Vol. 11, Issue 2 · 27 Aug 2011 · 7,894 accessesView PDFCite
Research ArticleOpen accessIn the abstractPerceived Workplace Culture as an Antecedent of Job Stress: The Mediating Role of Work-Family ConflictAminah Ahmad, Zoharah OmarProblem statement: Few studies have tested the mediating effect of work-family conflict on the relationship between workplace culture and job stress. Approach: This study tested a mediation model consisting of job stress as the dependent variable, perceived family-supportive work culture as the independent variable and work-family conflict as the mediator. Data were gathered from 693 employees from private service organizations … …Journal of Social Sciences, Vol. 6, Issue 3 · 30 Sep 2010 · 8,151 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Mediating Effect of Work-Family Conflict on the Relationship Between Locus of Control and Job SatisfactionNoryati Ngah, Aminah Ahmad, Maznah BabaProblem statement: Based on the literature review, few studies have tested the mediating effect of work-family conflict on the relationship between locus of control and job satisfaction. Approach: This study tested a mediation model consisting of job satisfaction as the dependent variable, locus of control as the independent variable and work-family conflict as the mediator. Data were gathered from 159 … …Journal of Social Sciences, Vol. 5, Issue 4 · 31 Dec 2009 · 7,782 accessesView PDFCite