6 articles for “Lymphoblastic leukemia”

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Research ArticleOpen accessPhrase in the titleUse of Novel Triphenyltin (IV) Dithiocarbamate Compounds in Assessing the Cytotoxicity and Mode of Cell Death of Acute Lymphoblastic Leukemia Cell Lines, CCRF CEM (CCL-119)Normah Awang, Nur Hidayah Hasrin, Nurul Farahana Kamaludin et al.Chemotherapy and radiotherapy are often used to treat Acute Lymphoblastic Leukemia (ALL). However, the resistance problem of treatment using the current drug in ALL patients has decreased the effectiveness of such therapy. Therefore, a study needs to be conducted to identify the potential of new anticancer agents. Organotin (IV) dithiocarbamate, an organometallic compound, causes toxic effects on cancer cells in … …OnLine Journal of Biological Sciences, Vol. 23, Issue 2 · 10 Mar 2023 · 5,159 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsHematologic Cancer Cell Detection and Classification Using Optimized VGG-19 with Stratified K-fold Cross-ValidationHema Patel, Himal Shah, Gayatri Patel, Atul PatelThe most prevalent pediatric blood malignancy is acute lymphoblastic leukemia (ALL). ALL is a lethal disease in which patients have a lower survival rate. Its prompt detection and precise categorization are essential for successful treatment. Manual microscopic diagnosis is laborious, prone to mistakes, and heavily reliant on specialized knowledge. With stratified 7-fold cross-validation, which assures an equal ratio of normal … …Journal of Computer Science, Vol. 21, Issue 11 · 24 Dec 2025 · 1,812 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsChildhood Cancer-a Hospital based study using Decision Tree TechniquesK. Kalaivani, R. ShanmugalakshmiProblem statement: Cancer is generally regarded as a disease of adults. But there being a higher proportion of childhood cancer (ALL-Acute Lymphoblastic Leukemia) in India. The incidence of childhood cancer has increased over the last 25 years, but the increase is much larger in females. The aim was to increase our understanding of the determinants of south Indian parental reactions … …Journal of Computer Science, Vol. 7, Issue 12 · 17 Oct 2011 · 7,057 accessesView PDF Cite

Review ArticleOpen accessIn the abstractBioprospection of Endophytic Bacteria Isolated from Mangrove Ecosystems and their Potential Biotechnological ApplicationsAlfian Mubaraq, Mariani Sembiring et al.The unique mangrove ecosystem hosts a variety of microorganism activities, including the crucial role of endophytic bacteria. Microorganisms found in mangrove forests play an important role in maintaining the biosphere by uniting various living beings and can be vital for future biotechnological applications. The use of microorganisms in the field of biotechnology is prevalent for producing antimicrobials against pathogenic bacteria … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 16 Aug 2024 · 4,996 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIntracellular L-Asparaginase from Bacillus sp. PG02: Purification, Biochemical Characterization and Evaluation of Optimum pH and TemperatureFatemeh Izadpanah Qeshmi, Mahsa Rahimzadeh, Sedigheh Javadpour, Manijeh PoodatBacterial L-asparaginases are amidohydrolases that act on L-asparagine and produce L-aspartate and ammonia. These enzymes have been used in treatment of lymphoblastic leukemia. In the present study, a novel strain, Bacillus sp. PG02 was explored for the production of intra-cellular L-asparaginase enzyme. The nitrogen source for L-asparaginase production was L-asparagine. New intracellular L-asparaginase was purified using ion exchange chromatography and … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 1 · 26 Nov 2015 · 7,480 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAge Difference in Immunophenotype of Acute LeukemiaKazunori Nakase, Mary Sartor, Kenneth BradstockWe examined the immunophenotype of 880 cases with acute leukemia and analyzed their age difference in relation to the morphological subtype and the karyotype. We divided the patients into 3 age groups: child (0-15 years), adult (16-59 years) and elderly (60 years and older) group. The diagnoses based on the French-American-British (FAB) criteria and the immunophenotype as follows: 453 patients … …American Journal of Immunology, Vol. 2, Issue 3 · 30 Sep 2006 · 6,941 accessesView PDF Cite