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34 articles for “Low-Density Lipoprotein”
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Research ArticleOpen accessPhrase in the titleEffects of Atorvastatin on Oxidized Low-Density Lipoprotein-induced Proliferation, Apoptosis, and Matrix Metalloproteinase-9 Expression in Human MacrophagesBensheng Liu, Huifan Li, Yan Wang, Li ZhangAtorvastatin (ATV), an HMG-CoA reductase inhibitor, is utilized in the treatment of atherosclerotic diseases. Mononuclear Macrophages (MMs) are critical immune cells involved in atherosclerosis progression, participating in processes such as foam cell formation, cytokine secretion, and the development of fibrous cap and lipid core. To further elucidate the mechanism by which ATV exerts its therapeutic effects on atherosclerosis through the … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 18 Nov 2025 · 2,133 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleStudy the Effect of Extracted Low-Density Lipoprotein from Egg Yolk on the Cryopreservation of Nguni Bull SemenMduduzi M. Tshabalala, Masindi Lottus Mphaphathi, Khathutshedzo A. Nephawe et al.The mechanism on how Egg Yolk (EY) helps sperm to survive the low temperature outside the animal body during cryopreservation and thawing process is not yet known. It is usually believed that the Low-Density Lipoprotein (LDL) is the major component that provides protection. The present study was undertaken to assess the cryo-protective effect of different concentrations (6, 8, 10 and … …American Journal of Animal and Veterinary Sciences, Vol. 16, Issue 3 · 13 Sep 2021 · 6,915 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleOxidized Low-density Lipoprotein Upregulates GM2 Activator Protein Gene ExpressionHidekatsu Yanai, Hiroshi Yoshida, Hironobu Fujiwara et al.Oxidized low-density lipoprotein (LDL) has been shown to be a powerful regulator of gene expression in monocyte-derived macrophage. To determine the effects of oxidized LDL on macrophage gene expression, macrophages incubated with native or oxidized LDL were analyzed by differential display technique. The differentially expressed cDNA (387 bp) fragment by oxidized LDL showed 100% homology to the part of 3’-untranslated … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 7,324 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleSubfractions of Low-Density-Lipoprotein: Which is the Most Atherogenic?Anastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Mikhail Аleksandrovich Popov et al.Atherosclerosis is a widespread disease of the arteries, which manifests itself in the narrowing of the lumen of the vessel due to the formation of plaque on its walls. Despite an impressive history of study, atherosclerosis still leaves room for researchers. This is realized due to the complexity of pathogenesis, in which important roles are assigned to a variety of … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 3 Sep 2023 · 4,697 accessesView PDFCite
Research ArticleOpen accessIn the keywordsLipid Profile and Antioxidant Enzymes in Normal and Stressed Rat Fed with Palm OleinEqbal M.A. Dauqan, Aminah Abdullah, Halimah Abdullah SaniProblem statement: The objective of the study was to evaluate the effect of Red Palm Olein (RPO) and Palm Olein (PO) on lipid profile and antioxidant enzyme in normal and stressed rat. Approach: Thirty six Sprague Dawley male rats which were randomly divided into six groups of 6 rats per group (tree normal groups and three stressed groups) were treated … …American Journal of Applied Sciences, Vol. 9, Issue 7 · 18 May 2012 · 6,880 accessesView PDFCite
Research ArticleOpen accessIn the keywordsVitamin C Alleviates Chronic Chlorpyrifos Induced Alterations in Serum Lipids and Oxidative Parameters in Male Wistar RatsS. F. Ambali, M. Shittu, J. O. Ayo et al.Problem statement: Although the increase incidence of cardiovascular diseases, obesity and diabetes mellitus has been attributed to changing life style, the role of environmental contaminants is currently being given considerable attention. Pesticides, including Organophosphate (OP) insecticides are one of the most pervasive environmental contaminants that are deliberately released into the environment. Chlorpyrifos (CPF), a widely used OP insecticide has been … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 4 · 21 Feb 2012 · 7,576 accessesView PDFCite
Research ArticleOpen accessIn the keywordsStudy the Effects of Ramadan Fasting on the Serum Glucose and Lipid Profile among Healthy Jordanian StudentsKama Mohmoud Saleh MansiRamadan is the holiest month in the Islamic calendar and Muslims fast during this month. We designed this study to evaluate the effect of Ramadan fasting on plasma lipids profile and serum glucose among healthy Jordanian students. Ramadan fasting entails major changes in sleep pattern, physical activity and eating habits, which may cause changes in metabolism both in health and … …American Journal of Applied Sciences, Vol. 4, Issue 8 · 31 Aug 2007 · 8,463 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAlterations of HDL Subclasses in Different Lipid Levels of Men and WomenYuye Yang, Luchuan Yang, Mingde Fu et al.With the increase of plasma TG level, both in men and women, apoA-I concentrations of preβ1-HDL and HDL3a were significantly higher while HDL2a and HDL2b were significantly lower. Similarly, with the increase of plasma LDL-C level, apoA-Iconcentrations of preβ1-HDL, HDL3c(in men) and HDL3b were significantly higher while apoA-Iconcentrations of HDL2b were significantly lower. And with the decrease of plasma HDL-C, … …American Journal of Immunology, Vol. 1, Issue 2 · 30 Jun 2005 · 9,075 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Vitamin D Deficiency on Cardio Metabolic Ageing in Middle Aged Adults in India: A Comparative AnalysisSumit Kumar, Adithi K, Shailaja S MoodithayaAdvancing age is accompanied by a gradual deterioration in physiological function, resulting in an increased risk of chronic diseases and early mortality. Growing evidence suggests that inadequate vitamin D status may be associated with unfavourable metabolic and cardiovascular alterations. Nevertheless, information regarding the association of vitamin D status with integrated cardio-metabolic biomarkers of ageing in middle-aged adults is currently limited. … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 3 Sep 2026 · 732 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Vitamin E on Stress Resorption, Lipid Profile and Reproductive Performance of Sokoto Red GoatsKehinde Matthias OKUKPE, Ling Shing Wong, Geetha Subramaniam et al.Vitamin E (α-tocopherol) plays a critical role in animal nutrition as an antioxidant, contributing to anti-inflammatory responses, immune function, and gene expression regulation. This study aimed to determine the optimal dietary level of vitamin E to alleviate the effects of environmental stress in Sokoto Red Goats transported from their native dry savannah belt to the humid derived savanna belt of … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 20 Mar 2026 · 1,509 accessesView PDFCite