Research ArticleOpen accessPhrase in the titleEffects of Nitrogen Source on the Lipid Accumulation in Phaeodactylum TricornutumXiaojie Ren, Qi Yan, Song Li et al.Nitrogen source has an important influence on the growth and lipid synthesis of Phaeodactylum tricornutum. It affects lipid accumulation through global metabolic regulation. However, little research has been done on the correlation between other metabolites and lipid metabolism during the synthesis of Phaeodactylum tricornutum. In this study, we studied the effect of different nitrogen sources on lipid and other major … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 27 Jul 2020 · 6,913 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEffect of Adding Cellulose on Lipid Accumulation in Cellobiohydrolase and Delta-6 Desaturase Engineered Mucor circinelloides StrainsYao Zhang, Yanxia Wang et al.Despite microbial production of multifunctional gamma-linolenic acid (GLA) being an important and promising way, the high cost is still a major factor limiting industrial applications. Previously, we proposed a novel approach to promote the production of GLA from cellulose, a widely available and cheapest resource, by overexpression of the cellobiohydrolase (CBH2) and delta-6 desaturase (D6) in Mucor circinelloides. In the … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 13 Oct 2023 · 4,731 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Enzymatic Role of Lipid Metabolism in Yarrowia lipolytica Grown on GlycerolRuixue Wang, Feifei Xin, Yufei Chang et al.More attention has been paid to the production of commercial fatty acids by microbial fermentation. The basic biochemistry of lipid accumulation in oleaginous microorganisms under nitrogen limitation has been extensively studied. As an oleaginous microorganism, Yarrowia lipolytica can produce fatty acid-derived biofuels and biochemicals. However, the response of the enzymes in Y. lipolytica to glycerol remains unclear. Therefore, we aimed … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 2 · 17 Apr 2023 · 6,309 accessesView PDFCite
Literature ReviewOpen accessIn the abstractIntracranial Atherosclerotic Disease: Treatment Potential and Diagnostic OpportunitiesAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Anton Yuvenalievich Postnov et al.Atherosclerosis, characterized by the accumulation of atherosclerotic plaques within large arteries, substantially increases the risk of cardiovascular events, including ischemic stroke. Intracranial atherosclerotic disease (ICAD) represents a particularly significant clinical threat given its strong association with ischemic stroke across multiple intracranial arterial territories. This review provides a comprehensive analysis of the pathogenesis, diagnosis, and management of intracranial atherosclerosis. Special attention … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 5 May 2026 · 1,093 accessesView PDFCite
Review ArticleOpen accessIn the abstractRole of HDL in Atherogenesis: Cholesterol and AtheroprotectionAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Victor Yurievich Glanz et al.Atherosclerosis is a major global health burden, responsible for a significant proportion of cardiovascular morbidity and mortality worldwide. Its high prevalence and severe clinical consequences have made it a subject of extensive research. Despite considerable advances, the complexity of its pathogenesis continues to hinder the development of effective preventive strategies and therapeutic interventions. Current evidence implicates chronic inflammation, dysregulated lipid … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 3 Apr 2026 · 1,476 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Role of Ganoderma lucidum Polysaccharides Against Stress Induced by Heavy Metals in Caenorhabditis elegansHuixiu Ma, Dehui Dai, Guicai Chen, Weilian HuAli, H., Khan, E., & Ilahi, I. (2019). Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation. Journal of Chemistry, 2019, 6730305. https://doi.org/10.1155/2019/6730305 Aljerf, L., & Aljerf, N. (2023). Food products quality and nutrition in relation to public. Balancing health and disease. Progress in Nutrition, 25(1), e2023024. https://doi.org/10.23751/pn.v25i1.13928 Aljerf, L., Williams, M., Ajong, A. B., Onydinma, … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 18 May 2024 · 6,947 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Soybean Oil on Lipid Metabolism in Mucor circinelloides WJ11 by Metabolomic AnalysisCaili Sun, Aabid Manzoor Shah, Junhuan Yang et al.Oleaginous fungus Mucor circinelloides utilizes different carbon sources associated with sustainable production of lipids, using soybean oil as carbon source, the fungus accumulated more intracellular lipids. Nonetheless, the metabolic changes in M. circinelloides upon vegetable oil as main carbon source have not been yet reported. Therefore, this study was conducted to investigate the metabolomics of M. circinelloides WJ11 cultivated in … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 9 Apr 2021 · 7,199 accessesView PDFCite
Research ArticleOpen accessIn the abstractTwo Co-Expression Strategies for Eicosapentaenoic Acid Production in Mortierella alpinaXin Tang, Haiqin Chen, Xiaoke Zhang et al.The omega-3 long-chain Polyunsaturated Fatty Acid (PUFA) Eicosapentaenoic Acid (EPA) has beneficial effects on human health, leading to its use in health products and foods. The oleaginous microorganism Mortierella alpina has been used in the industrial production of Arachidonic Acid (AA). The omega-3 desaturase oPpFADS17 is a key enzyme in the bioconversion of AA to EPA from Phytophthora parasitica and … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 4 · 5 Dec 2019 · 7,480 accessesView PDFCite