5 results for “Knee Osteoarthritis”

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Research ArticleOpen accessPhrase in the titleAssessment of Therapeutic Effects of Platelet-Rich Plasma in Knee Osteoarthritis: Possible Role of Inflammatory CytokinesMohammed H. Hassan, Sawsan Abuhamdah et al.Osteoarthritis (OA) is a multifactorial disease that commonly affects the knee. Tumor Necrosis Factor-α (TNF-α) regulates inflammation during OA. Macrophage Migration Inhibitory Factor (MIF) may be involved in the pathophysiology of arthritis. Platelet-Rich Plasma (PRP) may reduce pain associated with OA. The present study assessed the possible therapeutic effects of PRP in patients with OA of the knee with varying … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 15 Jun 2021 · 6,987 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleAssociation of Polymorphism in Growth and Differentiation Factor 5 Gene with Osteoarthritis KneeAbhishek Mishra, Divya Sanghi, Amar Chandra Sharma et al.The present study investigated to identify the association of polymorphism in GDF-5 gene with osteoarthritis in North Indian population. In a case-control study, 300 cases with knee osteoarthritis and an equal number of age and gender matched healthy controls were included. Cases were diagnosed using the ACR Guidelines of Knee Osteoarthritis (KOA). Clinical symptoms were assessed with the knee specific … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 1 · 18 Mar 2013 · 9,417 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleAssessment of Risk of Falls in Elderly Patients with Osteoarthritis of the Knee and Low Back PainVictor Hugo do Vale Bastos, Marco Antonio Araujo Leite, Marco Orsini et al.This study aimed identify which groups of elderly are at higher risk of falls, with osteoarthritis (OA), low back pain or both conditions. 29 elderly were distributed in three groups: OA of the Knee (OAK), Low Back Pain (LBP) and the two events concomitantly (OL). Evaluation tools applied were: Mini Mental State Examination (MMSE), Visual Analogue Scale (VAS), Western Ontario … …Current Research in Medicine, Vol. 3, Issue 2 · 30 Aug 2012 · 7,271 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsComparison of Improved Semi-Automated Segmentation Technique with Manual Segmentation: Data from the Osteoarthritis InitiativeHong Seng Gan, Khairil Amir SayutiManual segmentation is the standard procedure in osteoarthritis study. However, this method is infamous for being excessive, time consuming and exhaustive. In this study, we overcame the problem of excessive expert interaction reported in manual segmentation by developing a semi-automated random walks technique with computer-aided labelling system. To minimize expert interaction, non-cartilage seeds were generated by using computer. Then, random … …American Journal of Applied Sciences, Vol. 13, Issue 11 · 24 Oct 2016 · 7,363 accessesView PDF Cite

Research ArticleOpen accessIn the abstractTHE IMPACT OF ANTIOXIDANTS ON INFLAMMATION AND OXIDATIVE STRESS MARKERS IN OSTEOARTHRITIS RAT MODEL: SCANNING ELECTRON MICROSCOPE INSIGHTSEl Hassan Heidar, FareedF Al Faya, Waleed N. Hassan et al.Osteoarthritis (OA) is characterized by degradation of matrix and destruction of articular cartilage. Articular chondrocytes are solely responsible for the production and maintenance of the extracellular matrix. Therefore, chondrocyte disruption is implicated in cartilage degeneration. Numerous studies have shown that antioxidant treatments are promising therapeutics in cases of OA. This study was designedto examine whether vitamin E protects rat articular … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 19 May 2014 · 7,616 accessesView PDF Cite