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26 articles for “Immunology”
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Research ArticleOpen accessEvery word in the titleThe Hypoxia-Inducible Factor-1α Signaling Pathway and its Relation to Cancer and ImmunologyBruno R.B. Pires, Andre L. Mencalha, Gerson M. Ferreira et al.Hypoxia-Inducible Factor 1 (HIF-1) is a transcription factor that is present in all metazoans from early embryonic development throughout adult life. It plays a major roles in the different stress responses that are triggered by low Oxygen (O2) levels and its expression is associated with cell survival. HIF-1 is a heterodimer protein that comprises the subunits HIF-1α and HIF-1β. The … …American Journal of Immunology, Vol. 10, Issue 4 · 17 Jan 2015 · 8,482 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDUAL ROLES OF CANCER CELL-EXPRESSED IMMUNOGLOBULINS IN CANCER IMMUNOLOGYGregory Lee, Cheng-Yuan Huang, Suefay Liu et al.While the expression of immunoglobulins and T cell receptors on cancer cells has been well-established for decades, the potential roles and mechanisms of action of these cancerous antigen receptors have not been fully elucidated. A monoclonal antibody designated as RP215, which reacts specifically with the carbohydrate-associated epitope located on the heavy chain region of cancerous immunoglobulins and T cell receptors, … …American Journal of Immunology, Vol. 10, Issue 3 · 2 Oct 2014 · 7,870 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAttempts to Stimulate Immunology Responses by Intramuscular and Intraperitoneal Delivery of EPS-Adjuvanted Mannheimiosis VaccineGhaith Hussein Mansour, Laith Abdul Razzak, Hassan Ibrahim Sheikh, Mohd Effendy Abd WahidThis study was conducted on 48 male Sprague Dawley rats to determine the immunological responses of experimental adjuvanted vaccines of Mannheimia haemolytica A2 (M. haemolytica A2) injection and to observe their protection level upon live M. haemolytica A2 challenge. Forty-eight clinically healthy Sprague Dawley rats were divided into four groups; Groups 1 and 2 were vaccinated intramuscularly and intraperitoneally, respectively, … …American Journal of Animal and Veterinary Sciences, Vol. 17, Issue 4 · 22 Dec 2022 · 5,352 accessesView PDFCite
Research NotesOpen accessEvery word in the titleCould the Hybrid form of Lecturing and Active Learning be used as a Curricular Tool for Medical Education of Immunology in Algeria?Kheir Eddine Kerboua, Kamal DjenouhatLecturing has been the predominant mode of instruction since universities were founded in Western Europe over 900 y ago and still the sole method of instruction in the developing countries. However, claiming that adopting a specific new method will have reproducible results regardless the population’s characteristics is simply not possible. In this study, we sought to demonstrate that hybrid form … …American Journal of Immunology, Vol. 15, Issue 1 · 6 Dec 2019 · 7,217 accessesView PDFCite
EditorialOpen accessEvery word in the titleIMMUNOLOGY IN BRAZIL: CHALLENGES AND OPPORTUNITIES FOR YOUNG SCIENTISTSCarolina PanisThe Brazilian research community has recently emerged as a scientific power. Brazil’s intellectual production has significantly increased in recent years, mostly due to the growing number of young scientists in the country. Approximately 10,000 individuals are conferred the PhD degree in Brazil annually, with corresponding publications of a significant number of research papers. Brazil’s contribution to scientific publications constitutes approximately … …American Journal of Immunology, Vol. 10, Issue 4 · 26 Sep 2014 · 7,158 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCancerous Immunoglobulins and CA215: Implications in Cancer ImmunologyGregory LeeImmunoglobulins are typically expressed by B cells in our normal immune system. However, certain normal human tissues, such as hyperplastic epithelial cells, cells of the immunologically privileged sites and the majority of cancer cells, have also been found to be sites of immunoglobulin production. Current research is lacking in regards to the differential immunoglobulin expression, the underling mechanisms of action … …American Journal of Immunology, Vol. 8, Issue 4 · 18 Sep 2012 · 8,942 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleImmunology of Septic Shock and Traumatic Injury: A ReviewWilliam Heuser, Marianne Frieri, Krishan Kumar, Anthony BoutinSepsis remains a major worldwide cause of morbidity and mortality and remains amongst the leading causes of death in medical Intensive Care Units (ICUs). Increasing injury severity associated with trauma is a significant independent risk factor for sepsis and many of these patients require intensive care unit resource utilization with increased rates of mortality. There are many postulated theories regarding … …American Journal of Immunology, Vol. 11, Issue 4 · 31 Dec 2015 · 7,003 accessesView PDFCite
EditorialOpen accessIn the keywordsChasing the Fat Demon: Fat Chance, Buddy?David L. Katz, Joachim Storsberg, Christian SchmidtScience is an interesting profession. At times, one could get caught up in his or her own world of thoughts, perception, far away from reality, sometimes referred to as the proverbial ivory tower (Lederberg, 1972). Science for the sake of science is, per se, not without merit, with our fragmented understanding of a given issue providing ample justification for experimentation … …American Journal of Immunology, Vol. 13, Issue 2 · 29 May 2017 · 8,134 accessesView PDFCite
EditorialOpen accessIn the keywordsChoice Meaning and Context: Two Sides of the Same Coin?Saadettin Sel, Joachim Storsberg, Mark A. Brown, Christian SchmidtThe human intellect is a powerful instrument to be applied to problems. Expressed differently, sharpening one’s acumen by regular exposure to conundra can be likened to exercising a muscle or refining a tool such as creating brushes to suit certain tasks. Such applications hinge on a reasonable understanding of a given problem and the presentation of opposing viewpoints of the … …American Journal of Immunology, Vol. 13, Issue 2 · 24 May 2017 · 6,923 accessesView PDFCite
EditorialOpen accessIn the keywordsWhere the Future is Being Made TodayMark A. Brown, Joachim Storsberg, Christian SchmidtGrowing up, I was fascinated by The Muppet Show and the adventures of Dr. Bunsen Honeydew and his assistant Beaker. Apparently, my feelings were not unique because Muppet characters are used to ease tensions associated with education about clinical interventions (Ramsay, 2014; Rohn, 2007). Yet the opening phrase 'Where the future is being made today' has, in my opinion, summed … …American Journal of Immunology, Vol. 12, Issue 2 · 28 Jun 2016 · 7,425 accessesView PDFCite