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55 articles for “Gut”

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Research ArticleOpen accessEvery word in the titleEffect of Metformin Treatment on Inflammatory Factors and Gut Microbial Diversity in Patients with Type II Diabetes MellitusLei Tong, Jingjing Zhang, Li Xiao Yue et al.With the persistent rise in the prevalence of Type 2 Diabetes Mellitus (T2DM), traditional treatment evaluations have primarily focused on glycemic control, often overlooking the multidimensional effects of medications. As a first-line therapeutic agent, the anti-inflammatory effects and gut microbiota regulation mechanisms of metformin remain incompletely elucidated. This prospective cohort study established a metformin treatment group and a T2DM control … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 20 Jul 2026 · 774 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleTelomere Length and Gut Microbiota: Integrating Advanced Glycation End Products (Ages) With Artificial Intelligence for Understanding Premature AgingDiniwati Mukhtar, Hanifah HafsariPremature aging is characterized by an accelerated decline in biological functions, increasing the risk of chronic diseases. This review explores the interconnected roles of three critical biomarkers: Telomere Length, gut microbiota composition, and Advanced Glycation End Products (AGEs). These biomarkers exhibit bidirectional relationships, influencing one another and contributing to the aging process. Understanding their interplay provides valuable insights into the … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 3 Sep 2025 · 5,619 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSelenium Enriched Peanut Protein Alleviates Alcohol-Induced Liver Damage in Mice by Modulating the Composition of the Gut MicrobiotaLin Gao, Jiawei Yuan, Yuhuan Cheng et al.Alcohol Use Disorder (AUD) is one of leading external causes of mortality. Selenium-enriched Peanut Protein (SePP) is a type of Se compound present in Se-enriched plants. Our previous studies showed that SePP possesses potential therapeutic properties and could alleviate alcohol-induced AML-12 cytotoxicity. It spurred us to determine the underlying mechanisms and roles of SePP on gut microbiota. Here, ICR mice … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 23 Dec 2021 · 6,230 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAbsorption of Food Along the Guts of Parachanna obscura and Clarias gariepinusEunice O. Idowu, Adewumi A. Adejoke, Josephine B. Edward et al.The knowledge of feeding habit and absorption of food in the gut of fish is important for fish farmers to boost their production and meet the ever increasing demand for man consumption. The carbohydrate, protein and lipid contents of the food ingested and their absorption in the intestine of Parachanna obscura and Clarias gareipinus inhabiting Ogbese River in Ekiti State … …American Journal of Environmental Sciences, Vol. 16, Issue 1 · 26 Feb 2020 · 7,325 accessesView PDFCite
Case ReportOpen accessEvery word in the titleEffects on the Immune System of a Three-Month Consumption of an Extremely Diverse Probiotic Yogurt: Decrease of Serum Alpha-N-Acetylgalactosaminidase Activity, Detoxification and Gut Microbiota NormalizationJerry Blythe, Marco RuggieroIn this study, we describe the changes associated with the consumption of an extremely biodiverse probiotic yogurt in a 55-year-old female from South Vietnam. In August 2019, the subject voluntarily embarked on a three-month nutritional experience and decided to share her results with the goal of advancing scientific knowledge in the field of nutritional health. Consumption of this biodiverse probiotic … …American Journal of Immunology, Vol. 16, Issue 1 · 22 Oct 2020 · 9,697 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIsolation of the Antimicrobial Cyclic Peptide Subtilosin a from a Gut-Associated Bacillus subtilis StrainGhislain Schyns, Claudia R. Serra, Adriano O. Henriques et al.The endospore-forming Bacillus subtilis has been used as probiotics over the last 50 years. However, little is known on how Bacillus spp act in the gut compared to other well-characterized probiotics such as lactic acid bacteria. It is believed that the competitive exclusion of pathogens results from different mode of action notably the production of antimicrobial compounds such as bacteriocins. … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 7,678 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleProbiotics the Good Neighbor: Guarding the Gut Mucosal BarrierR. K. Rao, D. B. Polk, A. Seth, F. YanProblem statement: The disruption of gut barrier function plays a crucial role in the pathogenesis of not only gastrointestinal diseases, but also the diseases of liver and other organs. Mucosal protective factors that preserve the gut barrier integrity are beneficial in the prevention and treatment of such diseases. Probiotics is a group of helpful bacteria that protect the gastrointestinal mucosa … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 7,415 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Combined Phytohemagglutinin And α-Ketoglutarate Pharmacology Study of Gut Morphology and Growth in Older Adult RatsR. Filip, A. Harrison, S. G. PierzynowskiThis study has evaluated the effect of phytohaemagglutinin (PHA) in combination with alpha-ketoglutaric acid (AKG), on GI-tract morphology and N balance in adult rats. Rats, aged approx. 15 months, were assigned to one of four experimental groups, (1) Control group, (2) AKG group, (3) AKG+PHA 100% group and (4) AKG+PHA 1% group. AKG and AKG+PHA were administered via a stomach … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 4 · 31 Dec 2007 · 7,082 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMechanism of Mulberry's Effect on Intestinal Flora and MotilityHuizhen Zhao, Shijing Xie, Yuwen Li et al.Studies have indicated that mulberry consumption promotes intestinal motility and alleviates constipation, but the specific mechanism remains unclear. This study adopted a constipation mouse model to empirically analyze the effects of mulberry on intestinal motility, gut microbiota composition, and neurotransmitter levels, aiming to elucidate its mechanism of action. Key findings are as follows: 1) Compared with the model group, the … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 2 Jul 2026 · 1,189 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRelationship between Streptococcus gallolyticus Infective Endocarditis and Pre-Neoplastic Colorectal LesionsPau Vilardell, Sergio Moral, Josep Maria Frigola et al.Colorectal cancer is associated with Infective Endocarditis (IE) due to specific gut pathogens, such as Streptococcus gallolyticus subspecies, that use tumor presence as a point of blood entry. However, the association between Streptococcus gallolyticus related IE and pre-cancerous colorectal lesions like dysplastic adenomas is unclear. Seventy-one patients diagnosed with IE who underwent colonoscopy in the extension study during admission were … …American Journal of Infectious Diseases, Vol. 17, Issue 3 · 28 May 2021 · 7,131 accessesView PDFCite