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33 results for “Glucan”
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Research ArticleOpen accessEvery word in the titleImpact of B-Glucan Against Ehrlich Ascites Carcinoma Induced Renal Toxicity in MiceAhmed Flayyih Hasan, Azhar Azher Alankooshi et al.Several studies have been focused on identifying alternative medicines for the treatment of cancer. This study aimed to investigate the impact of B-Glucans extract (BG) against Ehrlich Ascites Carcinoma (EAC) induced toxicity and tissue damage in kidney. A total of 40 mice were assigned randomly to four groups (G1, control; G2, B-Glucans (75 mg/kg bw/day) orally for 2 weeks; G3, … …OnLine Journal of Biological Sciences, Vol. 23, Issue 1 · 23 Feb 2023 · 5,592 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDiabetic Retinopathy: Changes in Levels of Orosomucoids in Patients Supplemented with Beta Glucan and Vitamin DRichter Josef, Závorková Martina, Stiborova Ivana et al.The role of beta glucan in stimulating of various biological reactions is getting more and more attention. In this report, we focused on the effects of oral supplementation with beta glucan and vitamin D on changes in serum levels of orosomucoids in patients with diabetic retinopathy. We measured the level of orosomucoids and evaluated the effects of oral supplementation. In … …American Journal of Immunology, Vol. 14, Issue 1 · 15 Apr 2019 · 7,239 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRegulation of Gene Expression by β-GlucansMary O. Huff, Carolyn M. Klingeβ-D-glucans are diverse polysaccharides derived from plant cell walls, fungi and bacteria. β-D-glucans are composed of D-glucose monomers linked by (1-3) β-glycosidic bonds with varying amounts of (1-6) or (1-4) linked side chains that bind cell surface receptors ultimately triggering changes in intracellular pathways and gene transcription. β-D-glucans have anti-viral, immunomodulatory and anti-cancer activities. This article reviews the current identity … …American Journal of Immunology, Vol. 13, Issue 1 · 12 Apr 2017 · 7,553 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleGlucan Supplementation Regulates Secretory Immunity and StressRichter Josef, Stiborová Ivana, Král Vlastimil et al.Sixty-six children were supplemented with beta glucan and dietary nucleotides, another 63 children served as negative control. We evaluated the effects of these supplements on several aspects of secretory immunity such as levels of secretory IgA (SIgA), albumin and SIgA/albumin ratio. In addition, in order to monitor effects of physical challenges and compensatory treatments on stress and reparation of immunity, … …American Journal of Immunology, Vol. 13, Issue 1 · 30 Mar 2017 · 7,835 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleβ-Glucan in AllergiesSima Petr, Vetvicka VaclavMultiple effects of β-glucan are well established. Together with the effects on antibacterial and anticancer immunity, glucan has been shown to stimulate bone marrow cells, lower cholesterol and to protects against stress and some kinds of poisoning. However, despite literally thousands of papers describing biological effects of β-glucan, only limited attention has been focused on the role of β-glucan in … …American Journal of Immunology, Vol. 13, Issue 1 · 30 Mar 2017 · 8,981 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Novel Glucan-Sulforaphane Combination Stimulates Immune Response to Influenza in Mouse ModelVetvicka Vaclav, Vetvickova JanaInfluenza remains a serious health problem and causes approximately 500,000 deaths world-wide. With current available treatments offering neither dependable protection nor a rapid cure, many have focused their attention to alternative treatments. The aim of this study was to evaluate the possible effect of a novel maitake glucan-sulforaphane combination on immune response against influenza challenge in mice. We evaluated the … …American Journal of Immunology, Vol. 12, Issue 2 · 3 Aug 2016 · 7,933 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleβ1,3-GLUCAN ANTICANCER EFFICACIES AND SYNERGIES: A REVIEWStory Jenny, Vetvicka Vaclav, Angove Michaelβ1,3-glucans from fungi, cereals, seaweeds and bacteria have been shown to possess favourable biological and anti-carcinogenic activities including upregulation of phagocytosis, cytokine production enhancement, superoxide and nitrite production; antibody secretion and stimulation of signalling pathways associated with proto-oncogene expression. However, human dietary supplements containing β1,3-glucans vary in efficacy due to glucan source, the lifecycle stage of the source at extraction, … …American Journal of Immunology, Vol. 10, Issue 3 · 3 Sep 2014 · 8,759 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePlacebo-Driven Clinical Trials of Transfer Point Glucan #300 in Children with Chronic Respiratory Problems: III. Clinical FindingsVetvicka Vaclav, Richter Josef, Svozil Vladimir et al.The role of glucan in stimulation of immune reactions has been studied for decades. In this report we focused on the effects of orally administered glucan in children with chronic respiratory problems. We measured the physical endurance using a 6MWT test and the levels of eNO in 50 children aged 8-12 years and evaluated the effects of 100 mg/d oral … …American Journal of Immunology, Vol. 9, Issue 3 · 20 Aug 2013 · 9,028 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePlacebo-Driven Clinical Trials of Transfer Point Glucan #300 in Children with Chronic Respiratory Problems: Antibody ProductionVetvicka Vaclav, Richter Josef, Svozil Vladimir et al.The role of glucan in stimulation of immune reactions has been well-established. In this report, we focused on the antibody production in glucan-supplemented children with chronic respiratory problems. We measured the levels of salivary IgA, IgM and IgG in 40 children aged 8-12 years and evaluated the effects of 100 mg d-1 oral dose of glucan. We found a significant … …American Journal of Immunology, Vol. 9, Issue 2 · 5 Jun 2013 · 10,462 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleβ 1, 3-Glucan in Cancer TreatmentVaclav Vetvicka, J. VetvickovaNatural products, useful in preventing and/or treating various diseases, have been sought after throughout the man’s history. Despite some problems inherited from the natural source of glucans, there is extensive literature about their activities in animal tumor models. For the past 25 years, Japan has used several forms of mushroom-derived glucans in treating cancer patients. Additionally, close to twenty clinical … …American Journal of Immunology, Vol. 8, Issue 2 · 6 Jun 2012 · 8,871 accessesView PDFCite