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7 results for “Epigenetics”
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Literature ReviewOpen accessIn the keywordsMicroRNAs in Atherosclerosis: Key Players, Diagnostic Potential, and Therapeutic OpportunitiesAnastasia V Poznyak, Stanislav Anatolievich Antonov, Ulyana V. Rozhkova et al.Atherosclerosis is a significant contributor to cardiovascular diseases, often progressing silently over many years before clinical symptoms manifest. The multifaceted pathogenesis of atherosclerosis, involving processes such as endothelial dysfunction and inflammation, presents challenges in early diagnosis and effective treatment. MicroRNAs (miRNAs), a class of non-coding RNA molecules with post-transcriptional gene regulation abilities, have emerged as potential key players in atherosclerosis … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 25 Jul 2026 · 740 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMetabolic Potential Versus Genome SizeAtanas Todorov Atanasov, Dimitar Todorov ValevAlberch, P. (1983). Development and Evolution: Embryos, Genes, and Evolution. The Developmental-Genetic Basis of Evolutionary Change. Science, 221(4607), 257–258. https://doi.org/10.1126/science.221.4607.257 Andrews, C. B., Mackenzie, S. A., & Gregory, T. R. (2009). Genome size and wing parameters in passerine birds. Proceedings of the Royal Society B, 276(1654), 55–61. https://doi.org/10.1098/rspb.2008.1012 Atanasov, A. T. (2005). The linear alometric relationship between total metabolic energy … …Physics International, Vol. 13, Issue 1 · 15 Jun 2022 · 7,229 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEpigenetic Mechanisms in Hepatitis C Virus-Associated Hepatocellular Carcinoma: A Potential New Link Between Stem Cells, Virology and CancerQinghua Feng, Sajida Hassan, Trina Das et al.Recent studies suggest that epigenetic mechanisms are not only essential for the dynamic transcriptional regulation in embryonic and somatic stem cells, but are also actively involved in tumorigenesis: genes important for pluripotency are epigenetically regulated and aberrant epigenetic changes have been detected in virtually all human malignancies studied, including Hepatocellular Carcinoma (HCC). Infection with Hepatitis C Virus (HCV) is a … …Current Research in Medicine, Vol. 4, Issue 1 · 12 Mar 2013 · 8,038 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssociations of HSD17B1 Gene Expression with its DNA Methylation and Estradiol Level in Polycystic Ovary Syndrome Indonesian PatientsRina Puspita, Andon Hestiantoro et al.PCOS's origin and mechanism are still unknown. Epigenetics has been linked to PCOS in an increasing number of studies in recent years. The most extensively researched epigenetic alteration is DNA methylation. During organismal development, DNA methylation can control gene expression by altering transcription factor binding. The alterations in DNA methylation are directly associated with follicular development in PCOS. Studies show … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 8 Jan 2024 · 5,399 accessesView PDFCite
EditorialOpen accessIn the abstractChasing the Fat Demon: Fat Chance, Buddy?David L. Katz, Joachim Storsberg, Christian SchmidtScience is an interesting profession. At times, one could get caught up in his or her own world of thoughts, perception, far away from reality, sometimes referred to as the proverbial ivory tower (Lederberg, 1972). Science for the sake of science is, per se, not without merit, with our fragmented understanding of a given issue providing ample justification for experimentation … …American Journal of Immunology, Vol. 13, Issue 2 · 29 May 2017 · 8,134 accessesView PDFCite
EditorialOpen accessIn the abstractAre we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?Giuseppe Nocentini, Graziella Migliorati, Carlo RiccardiSince the end of the 1970s, interleukin 2 (IL-2) has been known as a key player in T cell expansion/activation (Watson et al., 1980). In the late 1980s, some groups used IL-2 to stimulate the immune systems of tumour patients (Jacobs et al., 1986). The idea seemed brilliant and several attempts were made, but the results were disappointing (Lim et … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 22 Oct 2015 · 7,625 accessesView PDFCite