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77 articles for “Diabetes mellitus”
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Research ArticleOpen accessPhrase in the titleEffect of Metformin Treatment on Inflammatory Factors and Gut Microbial Diversity in Patients with Type II Diabetes MellitusLei Tong, Jingjing Zhang, Li Xiao Yue et al.With the persistent rise in the prevalence of Type 2 Diabetes Mellitus (T2DM), traditional treatment evaluations have primarily focused on glycemic control, often overlooking the multidimensional effects of medications. As a first-line therapeutic agent, the anti-inflammatory effects and gut microbiota regulation mechanisms of metformin remain incompletely elucidated. This prospective cohort study established a metformin treatment group and a T2DM control … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 20 Jul 2026 · 774 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleGlutathione S-transferase (T1 & M1) Null Genotypes as Risk Determinants in Sudanese for Developing Type Two Diabetes MellitusGaafar Mahmoud, Hisham Mohamed Abdelrahim, Abed Al Salam Aljahmany, Eltayeb Mohamed Ahmed TayrabGlutathione S-transferases (GSTT1 and GSTM1) are globular proteins responsible for the detoxification of xenobiotics and the prevention of oxidative damage. Functional polymorphisms of the antioxidant glutathione and enzymes have a role in the pathogenicity of T2DM and its complications. The present study is aimed to assess association between GSTM1 and GSTT1 genetic polymorphisms with T2DM in Sudanese people. This case-control … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 16 Oct 2020 · 6,423 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleTreatment Adherence among Diabetes Mellitus Type II Patients at Ambulatory Clinics in the Western Region of Saudi Arabia: Descriptive Correlational StudyLouise de Villiers, Jehad O. HalabiDiabetes mellitus is a common problem in Saudi Arabia. Adherence to the pharmacological and lifestyle interventions regimens is essential for weight and glycaemic control, as well as prevention of co-morbidities. This study described the levels of treatment adherence among diabetes mellitus type II patients, explored the factors which influenced adherence and identified predictors of adherence. It was conducted in five … …International Journal of Research in Nursing, Vol. 6, Issue 2 · 1 Nov 2015 · 6,964 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleTHE EFFECT OF DIABETES MELLITUS ON THE CLINICAL AND MICRO-BIOLOGICAL OUTCOMES IN PATIENTS WITH ACUTE PYELONEPHRITISKathleen Lynch, Veena Venugopalan, Levita HidayatThere is some published evidence which suggests that the clinical outcomes and pathogens associated with Acute Pyelonephritis (AP) differ between diabetics and non-diabetics. However, current guidelines do not make treatment distinctions based on Diabetes Mellitus (DM) status. The objectives of this study were to identify the microbiological and clinical characteristics of hospitalized patients with AP and investigate differences between patients … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 6 May 2014 · 7,375 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEndothelial Dysfunction Induced by Type 2 Diabetes Mellitus and Fibrinolytic ActivityHussein F. SakrProblem statement: Type 2 diabetes mellitus is the world's largest systemic and metabolic disease. Endothelin (ET) was first described as a peptidergic endothelium-derived constricting factor. Endothelin-1 is one of the endothelial factors that is overexpressed in cases of endothelial dysfunction. The fibrinolytic system is present in plasma with the degradation of fibrin polymers in blood clots. It is a proteolytic … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 2 · 30 Jun 2010 · 7,729 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleHypoglycaemic Effects of Dietary Intake of Ripe and Unripe Lycopersicon esculentum (Tomatoes) on Streptozotocin-Induced Diabetes Mellitus in RatsA. M. Akinnuga, O. Bamidele, O. A. Ebunlomo et al.Ripe and unripe tomatoes have been implicated in prevention of chronic diseases such as cancer probably due to their antioxidant, antibiotic, antifungal and anti-inflammatory properties. Problem statement: This study was designed to investigate whether ripe and unripe tomatoes will have hypoglycaemic effect in a chronic disease such as diabetes mellitus that has been characterized with hyperglycaemia. Approach: Twenty albino Wistar … …OnLine Journal of Biological Sciences, Vol. 10, Issue 2 · 24 Mar 2010 · 8,764 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAtopic Dermatitis and Type 1 Diabetes Mellitus in Iranian ChildrenElham Ahmadi, Zahra Rahnama, Ali Rikhtegaran TehraniProblem statement: Atopic diseases, including asthma, eczema and allergic rhinitis, are characterized by a chronic inflammatory reaction mediated by T helper 2 cells, while type 1 diabetes mellitus is mediated by T helper 1 cells. Approach: The aim of this study was to compare the prevalence of atopic dermatitis between children with type 1 diabetes mellitus and age-matched controls. We … …American Journal of Immunology, Vol. 5, Issue 3 · 30 Sep 2009 · 8,010 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleTi: Cognitive Function in Diabetes Mellitus PatientsRostam SeyfaddiniNeuropathies are one of the most common complications in diabetic patients. Several studies determined relationship between cognitive disorders and diabetes mellitus (DM). The historical cohort study was designed to distinguish relation of DM and cognitive decrements. The Wisconsin Card Sort Test (WCST) and Mini-Mental Status Exam (MMSE) were conducted for evaluation of cognitive problems. Fifty diabetic patient and 48 control … …American Journal of Applied Sciences, Vol. 3, Issue 1 · 31 Jan 2006 · 6,935 accessesView PDFCite
Research ArticleOpen accessPhrase in the titlePrevalence of Herpesvirus 8 Infection in Type 2 Diabetes Mellitus PatientsA. Ingianni, F. Carta, A. Reina et al.In this study a possible relationship between the presence of type 2 diabetes (DM2) and the Human Herpesvirus 8 infection (HHV-8) has been evaluated. The presence of HHV-8 DNA was monitored by nested PCR and Southern blotting in peripheral blood leucocytes of DM2 patients admitted to the Diabetology and Metabolic Disease Service of the "S. Giovanni di Dio" Hospital (Cagliari, … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 7,923 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleThe Potential of VipAlbumin® to Chronic Inflammation in Type 2 Diabetes Mellitus Balb/C Mice ModelDinia Rizqi Dwijayanti, M. Sasmito Djati, Mansur Ibrahim, Muhaimin Rifa’iDiabetes Mellitus (DM) is one of diseases which have increasing number of sufferers every year. Almost all DM patients are type 2 DM. One of the causes of type 2 DM is a chronic inflammation due to an increase of circulating proinflammatory cytokines such as TNF-α, IFN-γ and IL-6. VipAlbumin® from snakehead fish extract is expected to be useful as … …American Journal of Immunology, Vol. 11, Issue 2 · 13 Jul 2015 · 7,612 accessesView PDFCite