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1 result for “DNA Hypermethylation”

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Review ArticleOpen accessEvery word in the titleHypermethylation and Hypomethylation of DNA: Implication for Diagnosis and Prognosis of Prostate CancerLubos Danisovic, Stanislav ZiaranProstate cancer belongs to the most common cancers and it is the second leading cause of cancer death in men. A genetic predisposition with epigenetic changes in DNA contributes to the development of the disease. DNA hypermethylation and hypomethylation belong to the most studied epigenetic changes in prostate cancer development. Both forms may lead to chromosomal instability and transcriptional gene … …OnLine Journal of Biological Sciences, Vol. 15, Issue 2 · 13 Jun 2015 · 6,528 accessesView PDFCite