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7 results for “Colitis”
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Research ArticleOpen accessEvery word in the titleImpact of Vitamin B17 Against Growth of Colitis Bearing Mice Induced Variations in Colon Structure, AFP, CEA and PCNA ImmunoreactivityGihan Hosny Abd Elsamie, Sabah Gaber El-Banna, Ehab Tousson et al.Colitis alludes to inflammation of the internal coating of the colon that accompanied clinically through abdominal pains, diarrhea, weight loss, nausea. Current study aimed to study the impact of vitamin B17 against growth of colitis bearing mice induced variations in colon structure, AFP, CEA and PCNA immune reactivity. Forty female Swiss albino mice separated into 4 groups (Control, vitamin B17, … …OnLine Journal of Biological Sciences, Vol. 21, Issue 3 · 23 Aug 2021 · 6,397 accessesView PDFCite
Case ReportOpen accessEvery word in the titleAbrus Precatorius Induced Hemorrhagic ColitisRajeshkumar Ganesan, Rajalakshmi EttiyanAbrus Precatorius commonly known as Rosary bead or Kundumani (Arena, 1986) is an irritant poison affecting almost all major systems of the body with more damage to the gastrointestinal system. The mortality rate is 10 to 15% for a lethal dose of just 1-2 crushed seeds. Following is the case report of hemorrhagic colitis due to the ingestion of a … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 13 Sep 2015 · 7,843 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCPI-1189 Protects against TNBS-induced Colitis in a Rodent ModelBeverley Greenwood-Van Meerveld, Karl TylerNitrone-related therapeutics (NRTs) represents a new class of molecules that may be effective in treating inflammatory conditions. The goal of this study was to examine the effect of CPI-1189 in a rat model of inflammatory bowel disease (IBD). Colonic inflammation was induced by an enema of trinitrobenzene sulfonic acid (TNBS). Saline-enema treated rats served as controls. After 3 days colonic … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 7,168 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCPI-1189 Protects Against Dextran Sulfate Sodium-induced Colitis in MiceBeverley Greenwood-Van Meerveld, Karl R. TylerNitrone-related therapeutics (NRTs) represent a new class of small molecules potentially effective in the treatment of inflammatory bowel disease (IBD) by protecting cells from damage caused by excess inflammation and/or oxidative stress. The goal of this study was to determine the efficacy and potency of CPI-1189, a novel therapeutic agent, in dextran sulfate sodium (DSS)-induced colitis in mice. Mice received … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 6,713 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPhysiological Effects of a Combination of Cinnulin with ProbioticsVetvicka Vaclav, Vetvickova JanaThe search for an optimal combination of natural immunomodulators led us to study the biological effects of the combination of a cinnamon extract Cinnulin PF and probiotic LactoSpore. We found that this combination has strong synergetic effects on phagocytosis and on regulation of cholesterol and blood sugar levels. In addition, the Cinnulin/LastoSpore combination also reduced intestinal damage in mouse model … …American Journal of Immunology, Vol. 9, Issue 4 · 2 Oct 2013 · 8,222 accessesView PDFCite
EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Bacillus subtilis 'PB6' (ATCC - PTA 6737) on Clostridium difficile Associated Diarrhea (CDAD) and Inflammatory Bowel Disease (IBD) in Animal ModelsEric Peys, Jerry Varghese, Ponusami Suresh et al.The administration of probiotic bacteria is emerging as a potential means of preventing the onset or recurrence of Clostridium difficile associated diarrhea (CDAD) and of attenuating inflammatory activity and preventing relapses in inflammatory bowel disease (IBD). We evaluated the efficacy of Bacillus subtilis 'PB6' (ATCC - PTA 6737) in a hamster model of antibiotic-induced CDAD and in a rat model … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,097 accessesView PDFCite