Research ArticleOpen accessIn the author namesProtective Role of Ganoderma lucidum Polysaccharides Against Stress Induced by Heavy Metals in Caenorhabditis elegansHuixiu Ma, Dehui Dai, Guicai Chen, Weilian HuAli, H., Khan, E., & Ilahi, I. (2019). Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation. Journal of Chemistry, 2019, 6730305. https://doi.org/10.1155/2019/6730305 Aljerf, L., & Aljerf, N. (2023). Food products quality and nutrition in relation to public. Balancing health and disease. Progress in Nutrition, 25(1), e2023024. https://doi.org/10.23751/pn.v25i1.13928 Aljerf, L., Williams, M., Ajong, A. B., Onydinma, … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 18 May 2024 · 6,949 accessesView PDFCite
Research ArticleOpen accessIn the author namesDihydroartemisinin Attenuates HBV-Induced Proliferation and Migration in LO2 cells via EMT Pathway ModulationYingde Nong, Caifang Ma, Wei Huang et al.Dihydroartemisinin (DHA), a derivative of artemisinin, possesses well-documented anti-inflammatory properties. This study investigated the inhibitory effects of DHA on hepatitis B virus (HBV)-induced cellular alterations in LO2 cells and elucidated underlying molecular mechanisms. Serum interleukin-6 (IL-6) levels were measured in HBV patients and analyzed for correlations with HBsAg, anti-HBs, and HBeAg. In vitro, LO2 cells were infected with clinical HBV … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 8 Jan 2026 · 2,079 accessesView PDFCite
Research ArticleOpen accessIn the author namesFerulic Acid in Chinese Herbal Medicine: Regulating Autophagy for Oxidative Damage ReductionZhiyuan Lv, Qiaozhen Zhao, Shanbin Chen et al.Ferulic Acid (FA) is the primary functional component in herbal plants and traditional fermented foods. To comprehend the mechanism of action of ferulic acid, in terms of its regulation of autophagy, antioxidants and the inhibition of inflammatory pathways, the study was conducted. Oxidatively damaged human-derived hepatocytes were treated with FA and the processing concentration of FA is from 50-800 μm. … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 1 Jun 2024 · 5,486 accessesView PDFCite
Research ArticleOpen accessIn the author namesChanges in Prothrombin Time and Platelet Parameters of Mice Treated with Vitamins C and EHongwei Li, Jing Cheng, Wei Wang et al.This study aims to elucidate the influence of supplementation with different doses of Vitamin C (VC) and Vitamin E (VE) on Prothrombin Time (PT) in mice; forty eight mice are randomly divided into six treatment groups, which are fed different dose VC and VE except for control Check (CK) for eight weeks. Blood samples are obtained from the mouse canthus … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 15 Apr 2020 · 7,090 accessesView PDFCite
Research ArticleOpen accessIn the author namesTwo Co-Expression Strategies for Eicosapentaenoic Acid Production in Mortierella alpinaXin Tang, Haiqin Chen, Xiaoke Zhang et al.The omega-3 long-chain Polyunsaturated Fatty Acid (PUFA) Eicosapentaenoic Acid (EPA) has beneficial effects on human health, leading to its use in health products and foods. The oleaginous microorganism Mortierella alpina has been used in the industrial production of Arachidonic Acid (AA). The omega-3 desaturase oPpFADS17 is a key enzyme in the bioconversion of AA to EPA from Phytophthora parasitica and … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 4 · 5 Dec 2019 · 7,482 accessesView PDFCite
Research ArticleOpen accessIn the author namesResponse of Root Growth and Root Border Cell Characteristics of Hemerocallis fulva to NaCl StressJinxiu He, Yongxu Qiao et al.Taking three Hemerocallis cultivars ('Jingzhouhua', 'Qingchong', 'Changzuizihua') with different salt tolerance as materials, the effects of 0-200 mmol/L NaCl on root morphology and Root Border Cell (RBC) characteristics were investigated using hydroponic and root suspension culture methods and one-way analysis of variance (ANOVA). The results showed that the root morphology indicators and activity of the high-salt-tolerant 'Jingzhouhua' decreased less than … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 27 Oct 2026 · 80 accessesView PDFCite
Research ArticleOpen accessIn the author namesAnaerobic Fermentation for Ceftriaxone Sodium Degradation in Excess Sludge: pH-Dependent Performance, Metabolite Formation, and Microbial Community DynamicsWeiwei Li, Hong Niu, Yonghui Zhang et al.The accumulation of ceftriaxone sodium (CTX), a third-generation cephalosporin antibiotic, in wastewater and sludge poses significant environmental and health risks, necessitating effective degradation strategies. This study investigated anaerobic fermentation of excess sludge (12,000-14,000 mg/L) spiked with 15 mg/L CTX under varying pH conditions (4, 7, 10, 12) to evaluate sludge reduction, metabolite formation, and microbial community dynamics. Results demonstrated that … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 31 Jul 2026 · 865 accessesView PDFCite
Research ArticleOpen accessIn the author namesCrop Disease Detection via an Improved Residual NetworkGuolin Chen, Weifeng Liu, Xinyu Zou, Xiaoxia LiDeep learning has shown substantial potential across many domains, and crop disease detection is no exception. This study investigates the application of deep learning to crop disease detection, systematically evaluating the performance of convolutional neural networks of different depths. Building on the classical ResNet-50 as the base model, we introduce a Squeeze-and-Excitation (SE) attention mechanism to enhance feature extraction. The … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 31 Jul 2026 · 905 accessesView PDFCite
Research ArticleOpen accessIn the author namesPurification, Structural Characterization and Anti-Aging and Stress Activities of Cordyceps Mycelium Polysaccharides from Paecilomyces HepialiXiaokang Hu, Huixiu Ma, Guicai Chen et al.This study identified and characterized the bioactive polysaccharide components from Cordyceps mycelium powder (CMP) derived from Paecilomyces hepiali, evaluating their anti-aging and stress-protective activities. Initial screening using Drosophila melanogaster revealed that crude Cordyceps polysaccharides (CCP) exhibited comparable effects to CMP and Cordyceps aqueous extracts (CAE) on natural lifespan and UV stress resistance, suggesting CCP as the primary bioactive component. CCP … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 16 Feb 2026 · 1,702 accessesView PDFCite
Research NotesOpen accessIn the author namesAn Artificial Design Technique to Optimize Signal PeptideGao Cui-Fang, Wang Sen, Tian Feng-Wei et al.To determine optimal artificial signal peptide candidates for the possibility of creating high levels of secretion of heterologous proteins, substitution and redesign of amino acid sequences in the H-domain of the signal peptide was theoretically attempted. The method was based on comprehensive score matrix and Markov transfer matrix, which can make the artificial sequences maintain the structural characteristics and original … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 3 · 21 Jul 2017 · 8,069 accessesView PDFCite