Changes in Prothrombin Time and Platelet Parameters of Mice Treated with Vitamins C and E
Hongwei Li1, Jing Cheng1, Wei Wang1, Xiangcui Chen1, Tongbing Qi1, Xinzhuo Tu1, Jing Zhang1, Weitong Cui1 & Qinglu Wang1 Show affiliations
- Qilu Medical University, China
American Journal of Biochemistry and Biotechnology, Volume 16, Issue 2, pp. 170–176 · doi.org/10.3844/ajbbsp.2020.170.176
Abstract
This study aims to elucidate the influence of supplementation with different doses of Vitamin C (VC) and Vitamin E (VE) on Prothrombin Time (PT) in mice; forty eight mice are randomly divided into six treatment groups, which are fed different dose VC and VE except for control Check (CK) for eight weeks. Blood samples are obtained from the mouse canthus to measure PT and platelet parameters. Administration of different doses of VC and VE to mice cause coagulation function damage.
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Li, H., Cheng, J., Wang, W., Chen, X., Qi, T., Tu, X., Zhang, J., Cui, W. & Wang, Q. (2020). Changes in Prothrombin Time and Platelet Parameters of Mice Treated with Vitamins C and E. American Journal of Biochemistry and Biotechnology, 16(2), 170–176. https://doi.org/10.3844/ajbbsp.2020.170.176
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