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Author

Wang Sen

Jiangnan University, China
1 article in our journals

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Research NotesOpen accessAn Artificial Design Technique to Optimize Signal PeptideGao Cui-Fang, Wang Sen, Tian Feng-Wei et al.To determine optimal artificial signal peptide candidates for the possibility of creating high levels of secretion of heterologous proteins, substitution and redesign of amino acid sequences in the H-domain of the signal peptide was theoretically attempted. The method was based on comprehensive score matrix and Markov transfer matrix, which can make the artificial sequences maintain the structural characteristics and original … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 3 · 21 Jul 2017 · 8,069 accessesView PDFCite