15 results for “Cardiac Muscle”

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InvestigationOpen accessPhrase in the titleEffects of Recombinant Toxin Phospholipase D in Cardiac Muscle of RatsJoao Victor Capelli Peixoto, Fernando Augusto Lavezzo Dias, Carlos Estevan Nolf Damiani et al.Loxoceles spiders gender are worldwide spread and its bites can cause dermonecrosis or even a systemic effect (hemolysis, kidney and liver injury). It is believed that phospholipase D, the main component present in the venom, could be responsible for the injury. In this study, we used a recombinant form of phospholipase D (rLiD1) and evaluated its direct and systemic effects … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 2 Jun 2015 · 6,959 accessesView PDF Cite

Research ArticleOpen accessPhrase in the titleMethodological Approach to Developing a Model of Interference-Free Processing of Multichannel Records of the Electrical Cardiological Impulse to Determine Episodes of Cardiac Muscle IschemiaSergey Alexandrovich Sheptunov, Alexander Nikolaevich Muranov, Abas Khasanovich Lampezhev, Tagirbek Gaidarbekovich AslanovThis study considered a set of topical issues aimed at improving the methodology of the early recognition of episodes of myocardial ischemia. It aims to solve a set of problems in the substantiation and development of a methodological approach for building a model of interference-free processing of multichannel electrocardio signal recordings. Based on theoretical and experimental studies, this will create … …Journal of Computer Science, Vol. 21, Issue 5 · 14 Apr 2025 · 4,922 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsSynthesis and Calcium Channel Blocking Activity of 1, 4-Dihydropyridine Derivatives Containing Ester Substitute and Phenyl Carbamoyl GroupBassem Sadek, Khairi Mustafa Salem Fahelelbom, Laurentiu Morusciag, Sigurd ElzProblem statement: Several studies on the synthesis of new nifedipine analogs have been carried out, but the literature reveled that no study on the synthesis and calcium channel blocking activity of the substituted ester with an amide (5-phenylcarbamoyl) moiety has been reported. Approach: Six new derivatives of m-nifedipine have been successfully synthesized by substituting an ester moiety with an amide … …American Journal of Applied Sciences, Vol. 8, Issue 4 · 18 Apr 2011 · 8,253 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAlgorithmization of Electrostatic Model for Solving the Direct Problem of ElectrographyTagirbek Gaidarbekovich Aslanov, Naur Zamirovich Ivanov, Shamil Shamil`evich Anudinov, Tatiana Vladimirovna KarlovaAn analysis of the creation and implementation of algorithms to control cardiological processes occurring in the cardiovascular system using software and hardware diagnostic systems is a required activity. This study considers ways to improve the methods of medical data processing using electronic diagnostic systems, relying on existing methods of mathematical simulation of human body states. This study describes the development … …Journal of Computer Science, Vol. 21, Issue 4 · 7 Mar 2025 · 5,337 accessesView PDF Cite

Research ArticleOpen accessIn the abstractTechnique for In-Vivo Measurements of Heart Deformation Using Digital Image CorrelationRonald B. Bucinell, Matthew T. Adams, Mcolisi Dlamini, Leo J. FleishmanMany techniques used to measure the deformation of biological tissue are inadequate for measuring deformations of hearts in vivo. Bull Frogs (Rana Catesbeiana) were double-pithed and dissected to expose the amphibian heart for the measurements conducted in this study. White titanium dioxide powder and black charcoal were applied to the surface of the heart to create an artificial surface pattern … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 14 Dec 2016 · 7,952 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Body Calming and Body Vitalizing Effects of Vernonia Amygdalina Leaf Extract and Leaf Powder and their MechanismsUtoh-Nedosa Uchechukwu AnastasiaProblem statement: Vernonia amygdalina (V. amygdalina) leaf soup is regarded by the indigenous Igbo people of South Eastern Nigeria as their best leafy vegetable soup. Despite the bitterness of the bitter leaf soup, the native eaters of the soup feel very content when they eat pounded carbohydrate foods with it. Oral V. amygdalina leaf extract was taken methodically in this … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 3 · 20 Sep 2011 · 8,165 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAdiponectin mRNA Expression in the Cat (Felis domesticus)Angela L. Lusby, Stephen A. Kania, Joseph W. Bartges, Claudia A. KirkProblem statement: Adiponectin is a hormone expressed from adipose tissue in people, rodents and dogs. Adiponectin has anti-inflammatory action with beneficial effects on cardiovascular health and insulin sensitivity. With increasing fat mass, adiponectin concentrations paradoxically decrease. Adiponectin’s role in metabolism and diabetes mellitus is of interest in feline medicine because cats are susceptible to developing type II diabetes with weight … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 4 · 27 Dec 2010 · 7,787 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCardiac Depression Produced by L-Arginine and Phosphodiestrase Inhibitor on Isolated Mammalian Rabbit Heart: Function of Cyclic Guanosine Monophosphate (cGMP)Hussein F. Sakr, Fahaid Al-Hashem, Mahmoud Al-Khateeb et al.Problem statement: Cyclic guanosine 3',5'-monophosphate cGMP is one the important second messengers that determines the cardiomyocyte activity and its role in healthy and diseased cardiac muscle is still controversial. We are reporting the effect of adding L-arginine, the NO donor that stimulates cGMP production and Sildenafil citrate (phosphodiestrase inhibitor) that inhibits cGMP hydrolyis on isolated rabbit’s heart to answer: Is … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 8,184 accessesView PDF Cite

Research ArticleOpen accessIn the abstractModulation of Insulin Receptor Substrate-1 and Some Inflammatory Variables in Hyperinsulinemic Rats Treated with Cinnamon ExtractMohamed H. Mahfouz, Hala M. Ghanem, Mona A. MohamedCinnamon Extract (CE) has shown to be generally safe when ingested and to have many pharmacological properties. Problem statement: Study the effects of daily intake of CE on the modulation of hepatic, cardiac Insulin Receptor Substrate-1 (IRS-1) and their relations to some inflammatory variables in hyperinsulinemic rats. Approach: The influence of CE administered orally was studied in hyperinsulinemic rats. Eighteen … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 1 · 31 Mar 2010 · 7,814 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCardioprotective Effect of Cucumis trigonus Roxb on Isoproterenol-Induced Myocardial Infarction in RatB. S. Thippeswamy, S. P. Thakker, S. Tubachi et al.Problem statement: Cucumis trigonus Roxb fruit is used for various ailments in Indian traditional system of medicine such as anthelmintic, liver tonic, cardio tonic, appetizer, expectorant and intellect promoting. However, there is lack of information regarding the effect of Cucumis trigonus on the cardiac changes associated with ISO induced myocardial infarction. Approach: The present study was designed to evaluate the … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 2 · 30 Jun 2009 · 11,555 accessesView PDF Cite