4 results for “CRISPR-Cas9”

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Review ArticleOpen accessIn the keywordsDecoding Late Blight of Potato and Tomato: Insights into Pathogen Dynamics, Host Interactions and Emerging SolutionsHumayra Ferdus, Mahabuba Mostafa, Dodi Al Sharif, Md. Motaher HossainThe oomycete Phytophthora infestans is the source of late blight, a devastating disease that significantly impacts on tomato and potato cultivation worldwide, threatening food security and causing considerable economic losses. This review explores the epidemiological dynamics of late blight, focusing on the pathogen's life cycle, reproductive strategies, and molecular pathogenesis. Traditional management strategies, including cultural practices, host resistance, and biocontrol … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 5 Feb 2026 · 2,537 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsProposal of a Genome Editing System for Genetic Resistance to Tomato Spotted Wilt VirusFederico Martinelli, Giovanni Grillone, Filippo SgroiViruses provoke considerable economical losses in agriculture. New molecular approaches to develop genetic resistance based on translational genomics and precision genetic modifications are highly expected. The type II Clustered, Regularly Interspaced Palindromic Repeats (CRISPR) system including Cas9 nuclease represent a promising and very powerful tool to specifically modulate the expression and activity of genes involved in biotic stress responses. In … …American Journal of Applied Sciences, Vol. 11, Issue 11 · 7 Jan 2015 · 7,689 accessesView PDF Cite

EditorialOpen accessIn the abstractEditorial Commentary: Challenge of Non–AIDS-Defining Cancers (NADCs), Focusing on Trans Activation Response Element (TAR) RNA Embedding ExosomesLechuang Chen, Ge JinGlobally, 37.9 million people were living with HIV at the end of 2018 (Organization, 2018). Cancer is a major cause of mortality and morbidity in AIDS patients and chronically HIV-infected people. With the aid of combination Antiretroviral Therapy (ART), people living with HIV (PLWH) have a longer life span. However, because the virus is not completely eradicated, PLWH under antiretroviral … …American Journal of Immunology, Vol. 15, Issue 1 · 28 Nov 2019 · 6,662 accessesView PDF Cite

EditorialOpen accessIn the abstractCRISPR-CAS SYSTEM: A FEASIBLE SOLUTION FOR GETTING RID OF PERSISTENT VIRAL INFECTION?Zhaohua ZhongMany viruses, including DNA and RNA viruses, can persistently replicate in the infected cells and cause a prolonged damage. Herpes viruses can be latent in its host cells. Human Immunodeficiency Virus (HIV) reversely transcripts its RNA genome to DNA and integrates to the host’s chromosome. Hepatitis B Virus (HBV) and Human Papilloma Virus (HPV) persistently stay in the host cells … …Current Research in Virology, Vol. 3, Issue 1 · 10 Nov 2014 · 12,620 accessesView PDF Cite