52 results for “CD4”

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Research ArticleOpen accessEvery word in the titleComparing the Diagnostics Accuracy of CD4+ T-Lymphocyte Count and Percent as a Surrogate Markers of Pediatric HIV DiseaseMusie Ghebremichael, Haben Michael, Jack Tubbs, Elijah PaintsilThe percentage CD4+ T-lymphocytes is used to monitor pediatric HIV disease. However, in resource-limited settings, enumerating the percentage of CD4+ T-lymphocytes is hampered by the lack of laboratory infrastructure and trained technicians. In this paper, we investigated the performances of the percentage and absolute CD4+ T-lymphocytes as markers of pediatric HIV disease progression using data from HIV-infected children enrolled through … …Journal of Mathematics and Statistics, Vol. 15, Issue 1 · 3 Apr 2019 · 7,521 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleA New Proposed Statistically-Derived Compromise Cut-off CD4 Count Value for HIV Patients to Start using ARVsMaria Mokgadi Lekganyane, Solly Matshonisa SeeletseThe study investigated the relationship between statistical outliers and the inconsistent values of the CD4 count recommended for starting the Antiretroviral Therapy (ART) by HIV-positive patients. Low CD4 counts imply a low immune system. It could be due to AIDS existence or closeness to death. An effective treatment to curb HIV impact is ART, which is recommended for low CD4 … …American Journal of Applied Sciences, Vol. 13, Issue 7 · 29 Jun 2016 · 7,333 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleCD2 Shown to Facilitate CD4+ Cell Differentiation during Visceral Leishmaniasis, a Receptor Based StudySukrat Sinha, Shanthy Sundaram, Sanjiva Bimal et al.This study addressed the role of CD2 on CD4+ T helper cells in relation to the TCRVα1 and CD70 in two groups of BALB/c mice viz control and infected (1×107 L. donovani promastigotes). The results showed with the downregulation of CD2 expression there is a pronounced decrease of TCRVα1 and CD70 on CD4+ cells in mice. An insight into the … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 28 Nov 2015 · 7,828 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleA Model for the CD4 Cell Counts in an HIV/AIDS Patient and its Application in Treatment InterventionsRichard O. Simwa, Joseph Y.T. MugishaThe number of CD4 white blood cells has been established as an important clinical marker of disease progression to acquired immunodeficiency syndrome (AIDS) for persons infected with human immunodeficiency virus (HIV). The number of CD4 cells per unit volume is expected to decrease with time since infection by the virus. However on introduction of treatment interventions, the process is expected … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,842 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleAssociation Between Circulating Early Endothelial Progenitors and CD4+CD25+ Regulatory T Cells: A Possible Cross-talk between Immunity and Angiogenesis?Shmuel Schwartzenberg, Adi Mor, Galia Luboshits et al.Regulatory T-cells (Treg) are a recently defined subset of CD4+ cells that can suppress inflammation and induce tolerance. Phenotypically, T-regs are characterized by a high level of expression of the IL-2 receptor alpha chain, CD25. Endothelial progenitor cells (EPCs) can transform into mature endothelial cells and promote vessel formation by inducing postnatal angiogenesis and vasculogenesis. Herein, we tested the hypothesis … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 6,902 accessesView PDF Cite

Case ReportOpen accessEvery word in the titleCryptococcal Meningoencephalitis in a Patient with Hyper IgM Syndrome Due to CD40 Deficiency: Case Report and Literature ReviewMaram Al-Banyan, Abdulhadi Alqahtani, Farrukh Sheikh et al.Hyper-IgM syndrome (HIGM) due to CD40 deficiency is a very rare form of combined immunodeficiency with increased susceptibility to opportunistic infections. Cryptococcus is an opportunistic infection usually affecting immunocompromised individuals. This is the first report to describe a patient with HIGM due to CD40 deficiency presenting with meningoencephalitis secondary to Cryptococcus infection. …American Journal of Infectious Diseases, Vol. 15, Issue 1 · 22 Feb 2019 · 7,741 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleExpression of the CD44 Protein in the Heart Valves Affected with Rheumatic Heart DiseaseR. Vijayalakshmi, S. Nayar, K.M. CherianProblem statement: The primary aim was to study the expression of CD44 protein in the heart valves removed surgically for either stenosis or regurgitation and to study the morphology of valves using histochemical staining. Approach: We studied 107 valves which were collected from the International Centre for Cardio Thoracic and Vascular Diseases. Results: Aortic and mitral valves were obtained from … …American Journal of Infectious Diseases, Vol. 6, Issue 4 · 31 Dec 2010 · 7,406 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsChronic and Acute Effect of Tramadol Intoxication on Some Immunological ParametersLoveday Udu Zebedee, Zaccheus Awortu Jeremiah, Nyebuchi Jonathan, Eni-Yimini Solomon AgoroTramadol intoxication is rapidly on the increase in Nigeria with unestablished short-term and long-term effects. The study was aimed at elucidating the dose-dependent effect of acute or chronic tramadol intoxication on some immunological parameters using male rats (Rattus norvegicus). A total of fifty adult rats were used for the study as indicated by Mead's Resource Equation. The study consisted of … …American Journal of Immunology, Vol. 17, Issue 1 · 24 Apr 2021 · 8,025 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsRisk Factors of Renal Aspergillosis in Pigeons (Columba livia): Field StudyBagus Uda Palgunadi, Kurniasih, Yos Adi PrakosoAspergillosis is the common infectious diseases in the avian species. Aspergillosis causes granulomatous lesions in the lung and upper respiratory system and rarely reported regarding its infection in the kidney. This study aims to analyse the risk factors of renal aspergillosis in the pigeon (Columba livia) and its association to aflatoxicosis and CD4+/ CD8+ depression. Twenty-dead pigeons, feed and litter … …American Journal of Animal and Veterinary Sciences, Vol. 14, Issue 2 · 13 Jun 2019 · 7,657 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsComparative Docking Analysis on Natural Compounds Versus a Synthetic Drug as a Therapeutic for Acquired Immuno Deficiency SyndromeSandhya R. Nair, R. Subhashini, B. ThiagarajanProblem statement: Acquired Immune Deficiency Syndrome (AIDS) is one of the worst pandemics affecting and spreading quickly all over the world with a high mortality rate. AIDS has been able to kill so many people due to the unique property of Human Immunodeficiency Virus (HIV) virus. It attacks the immune system of the victim there by not allowing the immune … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,323 accessesView PDF Cite