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American Journal of Infectious Diseases

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Case Report · Open access · Published 22 February 2019

Cryptococcal Meningoencephalitis in a Patient with Hyper IgM Syndrome Due to CD40 Deficiency: Case Report and Literature Review

Maram Al-Banyan1, Abdulhadi Alqahtani1, Farrukh Sheikh1, Agha M. Rehan Khaliq2, Hasan Al Rayes1, Ashraf Al-Tarifi1, Bandar Al-Saud1 & Rand K. Arnaout2

American Journal of Infectious Diseases, Volume 15, Issue 1, pp. 24–28 · doi.org/10.3844/ajidsp.2019.24.28

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Abstract

Hyper-IgM syndrome (HIGM) due to CD40 deficiency is a very rare form of combined immunodeficiency with increased susceptibility to opportunistic infections. Cryptococcus is an opportunistic infection usually affecting immunocompromised individuals. This is the first report to describe a patient with HIGM due to CD40 deficiency presenting with meningoencephalitis secondary to Cryptococcus infection.

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Al-Banyan, M., Alqahtani, A., Sheikh, F., Khaliq, A. M. R., Al Rayes, H., Al-Tarifi, A., Al-Saud, B. & Arnaout, R. K. (2019). Cryptococcal Meningoencephalitis in a Patient with Hyper IgM Syndrome Due to CD40 Deficiency: Case Report and Literature Review. American Journal of Infectious Diseases, 15(1), 24–28. https://doi.org/10.3844/ajidsp.2019.24.28

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Cryptococcal Meningoencephalitis in a Patient with Hyper IgM Syndrome Due to CD40 Deficiency: Case Report and Literature ReviewAmerican Journal of Infectious Diseases · Volume 15, Issue 1 · pp. 24–28 · CC BY 3.0Download