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4,046 results for “B1 gene”
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Research ArticleOpen accessPhrase in the titleAssociations of HSD17B1 Gene Expression with its DNA Methylation and Estradiol Level in Polycystic Ovary Syndrome Indonesian PatientsRina Puspita, Andon Hestiantoro et al.PCOS's origin and mechanism are still unknown. Epigenetics has been linked to PCOS in an increasing number of studies in recent years. The most extensively researched epigenetic alteration is DNA methylation. During organismal development, DNA methylation can control gene expression by altering transcription factor binding. The alterations in DNA methylation are directly associated with follicular development in PCOS. Studies show … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 8 Jan 2024 · 5,399 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleMinimum Free Energy Based Evaluation of mRNAs Secondary Structures Constructed by 18 Clinically Significant Exonic Single Nucleotide Polymorphisms (SNPs) and Haplotypes of 5 Missense SNPs of RB1 GeneSarder Nasir Uddin, Apurba Majumder, Khandker Khaldun Islam et al.Clinically significant 18 Single Nucleotide Polymorphisms (SNPs) from exon regions of Retinoblastoma gene (RB1) were analyzed to find out the structural variations in mRNAs. Online bioinformatic tools i.e., Vienna RNA, RNAfold were used for secondary structure analysis of mRNAs. Predicted minimum Free Energy Change (MFE) was calculated for mRNAs structures. It has been observed that the average of predicted MFE … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 21 Oct 2015 · 8,556 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleFrequency of Single Nucleotide Polymorphisms of the SLCO1B1 Gene in Slavic Population of Central EuropeMichaela Mikulová, Veronika Kramarova, Ján ChandogaThe organic anion transporting polypeptide 1B1 (encoded by SLCO1B1 gene) is involved in the active cellular influx of diverse endogenous compounds and several drugs, such as HMG-CoA reductase inhibitors (statins). Two common polymorphisms c.388A>G and c.521T>C in SLCO1B1 alter transport activity of this transporter and play an important role in the pharmaceutical response to many drugs. The aim of our … …OnLine Journal of Biological Sciences, Vol. 16, Issue 4 · 11 Dec 2016 · 7,308 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleComputational Prediction of Diabetic Nephropathy-Associated Comorbidities and Their Key Genes by Analyzing RNA-Seq DataChaity Paul, Md. Ashiq Uddin, Rupa Dey et al.Diabetic Nephropathy (DN) is a complex health condition that leads to various kidney diseases. According to the World Health Organization, over 2 million deaths have been reported due to diabetes and diabetes related kidney diseases in 2021. And at the recent 78th World Health Assembly, chronic kidney disease was reported to be one of the most common diabetes-related complications, and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 19 May 2026 · 1,667 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleGoats’ Litter Size Concerning Bone Morphogenetic Protein 15 Gene VariationsTebogo Letsukulo Percy Thepa, Thobela Louis Tyasi, Jones Ng’ambiBone morphogenetic protein 15 (BMP15), a member of the transforming growth factor-β (TGF-β) superfamily, plays essential roles in follicular development and ovulation. Single nucleotide polymorphisms (SNPs) in the BMP15 gene have been associated with litter size in multiple livestock species, yet no comprehensive systematic review has synthesized findings across goat breeds. This systematic review aimed to evaluate the association between … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 18 Feb 2026 · 1,405 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleInsulin-Like Growth Factor 1 Gene and Growth Traits Correlations in Sheep: A Systematic ReviewThabang Sako, Thobela Lousi Tyasi, Jones Ng’ambiAbousoliman, I., Reyer, H., Oster, M., Muráni, E., Mourad, M., Abdel-Salam Rashed, M., Mohamed, I., & Wimmers, K. (2020). Analysis of Candidate Genes for Growth and Milk Performance Traits in the Egyptian Barki Sheep. Animals, 10(2), 197. https://doi.org/10.3390/ani10020197 Al Qasimi, R., Hassan, A., & Khudair, B. Y. (2019). Effect of IGF-1 and GH Genes Polymorphism on Weights and Body Measurements … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 2 · 25 May 2024 · 5,755 accessesView PDFCite
Literature ReviewOpen accessEvery word in the titleSystematic Review of Single Nucleotide Polymorphisms of Cattle Beta-Lactoglobulin Gene and their Association with Milk Production TraitsThlarihani Cynthia Makamu, Thobela Louis TyasiThe application of molecular genetics technology to pinpoint certain DNA markers associated with commercially significant features is highly anticipated since it has the potential to enhance the effectiveness of breeding programs by selecting young animals early for use as future breeding stock. One of the main genes expressed in bovine milk is the Beta-Lactoglobulin Gene (βLG), and its polymorphism can … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 2 · 4 Mar 2024 · 5,811 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAlcohol Intubation and Synergistic Effect of Folic Acid and Egg Yolk Powder Solution on Alcohol Dehydrogenase [ADH] Class I Gene Expression and Single Nucleotide Polymorphism Frequency in Parent and Prenatal Alcohol Exposed Wistar RatsAdejoke Olukayode Obajuluwa, Oluyinka Ajibola Iyiola, Joseph Akintade Morakinyo et al.Point mutation detections in alcohol metabolizing genes could unravel molecular targets of gestational alcohol and epigenetic remodeling capacity of maternal nutrition, which underscores growth and health endpoints in Pre­natal Alcohol Exposed (PAE) fetuses. gene expression was assayed using sequenced target and internal control gene primers in a two-step thermal cycling process from isolated RNA in purely bred alcohol male and … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 22 Nov 2023 · 4,857 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDistribution of Alleles and Genotypes of ACE2 Gene Polymorphisms (rs2285666 and rs35803318) and Association with COVID-19 Among Populations in KazakhstanAnar Bisseneva, Konstantin Li, Gayane Pogossyan, Valeriya ProtasThere is still no definitive confirmation regarding the association between ACE2 gene polymorphisms and COVID-19. This study was conducted to analyze the distribution of alleles and genotypes of the ACE2 gene rs2285666 and rs35803318 two polymorphisms and their possible association with COVID-19 among two ethnic groups, namely, the Kazakhs and Eastern Slavs, residing within the same geographic area in the … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 31 Oct 2023 · 4,942 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIdentification of SBP Gene Family and Analysis of Expression Patterns Under Salt Stress in QuinoaWeihai Hou, Jianlin Wang, Zongyu Zhang et al.This study aimed to identify the Squamosa promoter Binding Protein (SBP) transcription factor from the whole genome of quinoa by analyzing its phylogenetic relationship, gene structure, chromosome location, gene replication, upstream cis-regulatory elements, tissue expression, and construction of the SBP protein interaction network, as well as the characteristics of its tissue expression pattern under salt stress. The researchers found that … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 21 Mar 2023 · 5,503 accessesView PDFCite