8 results for “Acute Kidney Injury”

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Case ReportOpen accessPhrase in the titleAlcohol-Induced Rhabdomyolysis Complicated by Hyponatremia and Acute Kidney Injury Following Minor Trauma: A Case ReportVinay Tulsian, Drupad Das, M Sukumar, Prasan Kumar PandaRhabdomyolysis from alcohol is established, but combined binge intake, minor trauma, and vomiting-induced hyponatremia is a complex clinical scenario. Case study: This case report describes a young male with a three-year history of alcohol consumption who presented with rhabdomyolysis following binge drinking and a mild traumatic fall. He experienced 10 to 15 episodes of vomiting post-alcohol intake, subsequently developing anasarca. … …American Journal of Pharmacology and Toxicology, Vol. 20, Issue 1 · 23 May 2026 · 1,700 accessesView PDF Cite

Research ArticleOpen accessPhrase in the titleEvaluation of the Renoprotective Effects of Valsartan in Methotrexate-Induced Acute Kidney Injury in RatsDina KutbiMethotrexate (MTX) is a widely used chemotherapeutic agent known for its nephrotoxic effects, which can lead to acute kidney injury in hospitalized patients. However, the mechanism by which MTX induces nephrotoxicity is not entirely clear, but it is believed to involve oxidative stress and direct toxic effects on renal tubules. Valsartan, an angiotensin II receptor blocker, has been shown to … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 4 May 2024 · 4,571 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsGynaecologic NephrologyNaheed Ansari, Jolina Santos, Fuad Spath, Srujana PolsaniRenal issues are commonly encountered in females. They can occur both in pregnant and nonpregnant females. Many physiologic changes occur during pregnancy to accommodate the growing fetus. Pregnancy is characterized by changes in blood pressure and expansion of total body volume which results in high glomerular filtration rate. The common renal problems seen in pregnant females are hypertension, proteinuria with … …Current Research in Medicine, Vol. 3, Issue 2 · 4 Aug 2012 · 7,314 accessesView PDF Cite

Case ReportOpen accessIn the keywordsAn Unusual Case of Leptospirosis Presenting as Glomerulonephritis With CrescentsFelipe Guedes Bezerra, Ana Flávia de Holanda Veloso, Yago Sucupira Amaral et al.Leptospirosis is a zoonosis caused by the spirochete Leptospira, which commonly affects the kidneys. Varied renal findings, most commonly tubulointerstitial nephritis, are found in human kidney biopsies and in vivo models. Remarkably, glomeruli are usually spared in this disease. However, some cases report evidence of glomerular damage. We describe a case of leptospirosis with fibroepithelial crescents, a rare histopathological finding. …American Journal of Infectious Diseases, Vol. 22, Issue 1 · 6 Aug 2026 · 1,011 accessesView PDF Cite

Case ReportOpen accessIn the keywordsSurvival Following Severe Paraquat Poisoning a Case Study from the Andaman and Nicobar IslandsShiv Shankar Singh, Colin Sanchez, Prasan Kumar PandaParaquat poisoning continues to pose a significant public health challenge in the Andaman and Nicobar Islands, largely due to its alarmingly high mortality rate. In this report, we present the case of a 39-year-old male farmer who ingested 30 mL of paraquat with the intent of suicide. Initially, the patient underwent prompt gastric lavage and exhibited relative stability. Upon admission, … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 22 Jan 2025 · 10,605 accessesView PDF Cite

Case ReportOpen accessIn the abstractEmphysematous Pyelonephritis with Abscesses Masquerading as an Ordinary Urinary Tract InfectionTasnim F. Imran, Frederick Yick, Ahmed H. Qavi et al.Emphysematous Pyelonephritis (EPN) is a rare, gas-forming infection of the renal parenchyma associated with significant morbidity and mortality. We report the case of a 39 year-old woman with uncontrolled diabetes who presented with abdominal pain, fevers and chills for one month. Physical exam was notable for dry oral mucosa and left costovertebral angle tenderness. Labs showed acute kidney injury and … …American Journal of Infectious Diseases, Vol. 11, Issue 4 · 22 Oct 2015 · 7,746 accessesView PDF Cite

Research ArticleOpen accessIn the abstractFactors Those Up Regulate Klotho and Glutathione Peroxidase-1 Gene Expression Improve Renal Function in Rats with Acute Renal FailureFatma E. El-Gendey, Shabaan A. Hemeda, Gamal A. Sosa, Naglaa F. AlhusseiniAcute Renal Failure (ARF) has traditionally been defined as the abrupt and progressive loss of kidney functions resulting in the retention of urea and other nitrogenous waste products associated with interstitial inflammation, tubular injury and increasing Tumor Necrosis Factor (TNF). Mortality in patients with ARF remains high >50% in severely ill patients. Klotho gene is a new anti-aging gene. Genetic … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 3 · 15 Aug 2015 · 7,097 accessesView PDF Cite

EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,737 accessesView PDF Cite