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Case Report · Open access · Published 6 August 2026

An Unusual Case of Leptospirosis Presenting as Glomerulonephritis With Crescents

Felipe Guedes Bezerra1, Ana Flávia de Holanda Veloso2, Yago Sucupira Amaral1, Thiago de Paula Pessoa Franco Silva2 & Anaiara Lucena Queiroz2

American Journal of Infectious Diseases, Volume 22, Issue 1, pp. 1–3 · doi.org/10.3844/ajidsp.2026.1.3

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Abstract

Leptospirosis is a zoonosis caused by the spirochete Leptospira, which commonly affects the kidneys. Varied renal findings, most commonly tubulointerstitial nephritis, are found in human kidney biopsies and in vivo models. Remarkably, glomeruli are usually spared in this disease. However, some cases report evidence of glomerular damage. We describe a case of leptospirosis with fibroepithelial crescents, a rare histopathological finding.

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Bezerra, F. G., Veloso, A. F. H., Amaral, Y. S., Silva, T. P. P. F. & Queiroz, A. L. (2026). An Unusual Case of Leptospirosis Presenting as Glomerulonephritis With Crescents. American Journal of Infectious Diseases, 22(1), 1–3. https://doi.org/10.3844/ajidsp.2026.1.3

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An Unusual Case of Leptospirosis Presenting as Glomerulonephritis With CrescentsAmerican Journal of Infectious Diseases · Volume 22, Issue 1 · pp. 1–3 · CC BY 4.0Download