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92 results for “Biomarker”
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Research ArticleOpen accessIn the abstractPaleolithic-Style Diet and Coronary Artery Disease: The Tissue is the Issue?Eri Toda, Takahashi Toru, R. B. Singh et al.Approach: While the Western diet is proatherogenic, Paleolithic-style diet may be protective against Cardiovascular Diseases (CVDs). Results: Western diet is characterized with energy dense, refined, foods with a high glycemic index (e.g., refined starches; biscuits and bread) and unhealthy lipids (e.g., trans fats, saturated fat, omega-6 rich oils) poor in omega-3 fatty acids, phytochemicals and fibre. These diets are known … …Current Research in Medicine, Vol. 3, Issue 2 · 10 Aug 2012 · 7,135 accessesView PDFCite
Research ArticleOpen accessIn the abstractPlatelets, Coagulation and Cancer: Multifaceted InteractionsT. Burnouf, H. A. GoubranApproach: Literature review of the multifaceted interactions between platelets, coagulation and cancer. Results: Over the years, the links existing between cancer development, progression and occurrence of metastasis on one side and coagulation on the other have become obvious. Tumors seems to activate platelets whereas, platelets, on the other hand, through their capacity to activate and release soluble factors and microparticles, … …Current Research in Medicine, Vol. 3, Issue 2 · 30 Jul 2012 · 7,613 accessesView PDFCite
Research ArticleOpen accessIn the abstractCross Validation Evaluation for Breast Cancer Prediction Using Multilayer Perceptron Neural NetworksShirin A. Mojarad, Satnam S. Dlay, Wai L. Woo, Gajanan V. SherbetProblem statement: The presence of metastasis in the regional lymph nodes is the most important factor in predicting prognosis in breast cancer. Many biomarkers have been identified that appear to relate to the aggressive behaviour of cancer. However, the nonlinear relation of these markers to nodal status and also the existence of complex interaction between markers have prohibited an accurate … …American Journal of Engineering and Applied Sciences, Vol. 4, Issue 4 · 20 Feb 2012 · 7,699 accessesView PDFCite
Research ArticleOpen accessIn the abstractLemon Pepper Fruit Extract (Zanthoxylum acanthopodium DC.) Suppresses the Expression of Inflammatory Mediators in Lipopolysaccharide-Induced Macrophages In VitroYanti, Theodorus Eko Pramudito, Nerissa Nuriasari, Katarina JulianaProblem statement: Lemon pepper fruits (Zanthoxylum acanthopodium DC.; Rutaceae) have been used as a traditional source against stomach ache by Batak people in North Sumatera province, Indonesia. However, its scientific evidence for treatment of inflammatory disorders particularly gastritis has not been reported. Approach: Here, we investigated the inhibitory effects of Lemon Pepper Fruit Extract (LPFE) against inflammatory biomarkers by conducting … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 4 · 14 Feb 2012 · 9,581 accessesView PDFCite
Research ArticleOpen accessIn the abstractC-Reactive Protein and Serum Procalcitonin Levels as Markers of Bacterial Upper Respiratory Tract InfectionsDiamantis P. Kofteridis, George Samonis, Alexander D. Karatzanis et al.Problem statement: Upper Respiratory Tract Infections (URTIs) are the most frequent of the community with major social and financial impact. Hence, early and proper diagnosis is of utmost importance. Biomarkers such as the circulating levels of Procalcitonin (PCT) have been shown to be elevated in systemic bacterial infections, but remain relatively low in viral infections and inflammatory diseases and have … …American Journal of Infectious Diseases, Vol. 5, Issue 4 · 31 Dec 2009 · 7,135 accessesView PDFCite
Research ArticleOpen accessIn the abstractCamel's Milk Alleviates Oxidative Stress and Lipid Peroxidation Induced by Chronic Aluminum Chloride Exposure in Rat's TestesFahaid H. Al-HashemProblem statement: The present study was carried out to examine the effectiveness of Camel’s milk in alleviating aluminum chloride (AlCl3)-induced oxidative stress and lipid peroxidation in rat testes. Approach: White albino male rats (230-250 g) were divided into three groups of 10 rats: A control group, treated with normal saline and two experimental groups, the AlCl3 treated group and the … …American Journal of Applied Sciences, Vol. 6, Issue 11 · 30 Nov 2009 · 7,429 accessesView PDFCite
Research ArticleOpen accessIn the abstractCamel's Milk Protects against Aluminum Chloride-Induced Toxicity in the Liver and Kidney of White Albino RatsFahaid Al-HashemProblem statement: Aluminum chloride (AlCl3) is commonly used in daily life but it can be potentially toxic. Therefore, the present study was carried out to investigate the protective effects of camel’s milk against aluminum-induced biochemical alterations and oxidative stress in the liver and kidney of white albino rats. Approach: White albino male rats (230-250 g) were divided into three groups … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 10,367 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvidence of Mitochondrial Dysfunction in Autism and Implications for TreatmentDaniel A. Rossignol, J. Jeffrey BradstreetClassical mitochondrial diseases occur in a subset of individuals with autism and are usually caused by genetic anomalies or mitochondrial respiratory pathway deficits. However, in many cases of autism, there is evidence of mitochondrial dysfunction (MtD) without the classic features associated with mitochondrial disease. MtD appears to be more common in autism and presents with less severe signs and symptoms. … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 16,373 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Novel Rodent Model of Autism: Intraventricular Infusions of Propionic Acid Increase Locomotor Activity and Induce Neuroinflammation and Oxidative Stress in Discrete Regions of Adult Rat BrainDerrick F. MacFabe, Karina Rodríguez-Capote, Jennifer E. Hoffman et al.Innate neuroinflammatory changes, increased oxidative stress and disorders of glutathione metabolism may be involved in the pathophysiology of autism spectrum disorders (ASD). Propionic acid (PPA) is a dietary and gut bacterial short chain fatty acid which can produce brain and behavioral changes reminiscent of ASD following intraventricular infusion in rats. Adult Long-Evans rats were given intraventricular infusions of either PPA … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 12,613 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Serological Gastric Biopsy: A Non-endoscopical/Histopathologic Diagnostic Approach in Management of the Dyspeptic PatientsR. A.K. Mahmoud, H. H. Morcos, A. A. Hegazi et al.Objective: To asses the sensitivity, specificity and the predictive value of a 'gastropanel' blood test, including serum pepsinogen I (S-PGI) and amidated gastrin-17 (S-G-17) in the diagnosis of atrophic gastritis most probably due to helicobacter pylori (Hp) and to compare the results of serology with the endoscopic/histopathologic findings as a gold standard diagnostic tool. This study comprised 86 dyspeptic outpatients … …American Journal of Immunology, Vol. 2, Issue 4 · 31 Dec 2006 · 7,131 accessesView PDFCite