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99 articles for “Pathogenesis”
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Research ArticleOpen accessIn the abstractThe Functional Effect of Kaempferia Parviflora on Ischemic Stroke in RatsWathita Phachonpai, Sinthuporn Maharun, Terdthai Tong-Un et al.Problem statement: Oxidative stress has been implicated as important factors in the pathogenesis of cerebral ischemia-induced behavioral deficits particularly memory. Growing attention is being paid to traditional medicinal plants possessing antioxidant activity, as they have been proved therapeutically/prophylactically fruitful against stroke condition. Present study provides evidence of the neroprotective effects of a Thai traditional herb, Kaempferia Parviflora (KP) extract, against … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 2 · 16 Mar 2012 · 8,740 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiomarkers of Oxidative DNA Damage and Soluble Fas/Fas Ligand in Type 2 Diabetic PatientsMohamed H. Mahfouz, Ibrahim A. Emara, Ghada A. OmarProblem statement: Involvement of oxidative stress in the pathogenesis of diabetic complications has been proposed. 8-hydroxy-2'-deoxyguanosine (8-OHdG) has been reported to serve as a new sensitive biomarker of the oxidative DNA damage in vivo. Apoptosis via Fas/Fas Ligand (FasL) interactions has been proposed to be a major T-cell-mediated effector mechanism in autoimmune diabetes. This study was undertaken to investigate whether … …American Journal of Applied Sciences, Vol. 9, Issue 4 · 3 Feb 2012 · 7,106 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Cardioprotective Diet in Acute Coronary SyndromeR. B. Singh, Suniti Dharwadkar, Fabien DeMeester et al.Problem statement: Nutritional factors appear to be quite important in the pathogenesis and prognosis among patients of Acute Myocardial Infarction (AMI) or Acute Coronary Syndrome (ACS). Increased consumption of proinflammatory foods; such as refined starches and sugar, trans fat, saturated fat and w-6 fatty acids may increase proinflammatory cytokines, oxidative stress and free fatty acids causing endothelial dysfunction. Approach: Columbus … …Current Research in Medicine, Vol. 2, Issue 2 · 15 Oct 2011 · 7,460 accessesView PDFCite
Research ArticleOpen accessIn the abstractS-Allyl-Cysteines Reduce Amelioration of Aluminum Induced Toxicity in RatsSadhana ShrivastavaProblem statement: Aluminum (Al) is a trivalent cation found in its ionic form in most kinds of animal tissues and in natural waters everywhere. Approach: It is a potent neurotoxin and has been associated in the pathogenesis of several clinical disorders including Alzheimer’s disease. Results: The aim of the study was to demonstrate the protective effect of S-Allyl-Cysteines (SAC) against … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 12 Aug 2011 · 7,748 accessesView PDFCite
Research ArticleOpen accessIn the abstractSuppression of Salicylic Acid-Mediated Plant Defense Responses During Initial Infection of Dyer's Woad by Puccinia thlaspeosBradley R. Kropp, Elizabeth ThomasProblem statement: Puccinia thlaspeos is a microcyclic rust pathogen that is being investigated as a potential biocontrol agent of the noxious weed, dyer’s woad (Isatis tinctoria). Although, the initial events in the colonization of dyer’s woad by the rust pathogen has been elucidated using scanning electron microscopy and PCR, little is known regarding the susceptibility response of this plant to … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 3 · 4 Aug 2011 · 8,033 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-β2 Glycoprotein-I Antibody in Acute Myocardial InfarctionMohammad Shojaei, Abdolreza Sotoodeh Jahromi, Hamideh Ebadat et al.Problem statement: Ischemic cardiac manifestations have been reported in a various percentage of patients with anti-phospholipid antibodies. Data concerning the relation between anti- Phospholipid (aPL) antibodies and myocardial infarction in subjects without evidence of overt autoimmune disease are conflicting. Anti-beta2 glycoprotein-I (anti-beta2-GPI) antibody is detected in various diseases like rheumatoid arthritis, systemic lupus erythematosus and anti-phospholipid antibody syndrome. The study … …American Journal of Applied Sciences, Vol. 8, Issue 8 · 18 Jul 2011 · 7,051 accessesView PDFCite
Research ArticleOpen accessIn the abstractScreening Neuropharmacological Activities of Kaempferia parviflora (Krachai Dam) in Healthy Adult Male RatsThaneeya Hawiset, Supaporn Muchimapura, Jintanaporn Wattanathorn, Bungorn SripanidkulchaiProblem statement: Although the global prevalence of psychological disorders is increasing continually, the efficacies of therapeutic strategies are still very limited. Oxidative stress has been implicated in the pathogenesis of psychiatric disorders and substance possessing antioxidant activity can alleviate the mentioned conditions. Therefore, we hypothesized that Kaempferia parviflora, a medicinal plant claimed for nerve tonic, also possessed the neuropharmacological activities … …American Journal of Applied Sciences, Vol. 8, Issue 7 · 24 Jun 2011 · 8,697 accessesView PDFCite
Research ArticleOpen accessIn the abstractFirst Report of Human Immunodeficiency Virus Type 1 Circulating Recombinant Form 02_AG Recombinant Strain of African Origin from North IndiaUjjwal Neogi, Vikas Sood, Arpita Choudhury et al.Problem statement: Human Immunodeficiency Virus Type-1 (HIV-1) displays extensive genetic diversity globally which poses a serious challenge in making efficacious vaccine and developing effective therapeutic interventions. HIV-1 epidemic in India is largely driven by genetic subtype C but lately a number of reports suggest the presence of circulating recombinant forms and unique recombinant forms from different states of India. Approach: … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 6,737 accessesView PDFCite
Research ArticleOpen accessIn the abstractα-Lipoic Acid Therapy Modulates Serum Levels of Some Trace Elements and Antioxidants in Type 2 Diabetic PatientsSalwa Kamal El-Nabarawy, Mona Abd El-Gelel Mohamed, Mohamed Mahmoud Ahmed, Ghada Hany El-ArabiProblem statement: The metabolism of several trace elements has been reported to alter in diabetes mellitus. The disturbance of their serum levels may have a role in the pathogenesis and progress of this disease. In addition, the reports about the status of antioxidants and antioxidant enzymes in diabetic patients are very contradictory. Though α-Lipoic Acid (LA) has long been touted … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 3 · 30 Sep 2010 · 7,762 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetermination of Adhesin Encoding Genes in Escherichia coli Isolates from Omphalitis of ChicksReza Ghanbarpour, Mahmood SalehiProblem statement: Omphalitis is one of the most common causes of mortality in chicks during the first week after hatching. Escherichia coli strains are the most common isolated bacteria from omphalitis cases of chickens. Bacterial colonization in the host cells surfaces is a critical first step in the pathogenesis of avian pathogenic Escherichia coli isolates. Thus the current study was … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 2 · 30 Jun 2010 · 9,557 accessesView PDFCite