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109 articles for “Mutation”
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EditorialOpen accessIn the abstractANTIBIOTIC RESISTANCE: A FRIGHTENING HEALTH DILEMMARuchi Tiwari, Kuldeep DhamaByarugaba, D.K., 2004. Antimicrobial resistance in developing countries and responsible risk factors. Int. J. Antimicrob. Agents, 24: 105-110. DOI: 10.1016/j.ijantimicag.2004.02.015 Cirz, R.T., J.K. Chin, D.R. Andes, V. de Crécy-Lagard and W.A. Craig et al., 2005. Inhibition of mutation and combating the evolution of antibiotic resistance. PLoS Biol., 3: e176-e176. DOI: 10.1371/journal.pbio.0030176 Dhama, K., S. Chakraborty, Mahima, M.Y. Wani and A.K. … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 3 · 26 Sep 2014 · 10,774 accessesView PDFCite
Research ArticleOpen accessIn the abstractINHIBITORY ACTIVITY OF POTENTOX AGAINST DNA GYRASE OF ENTEROBACTERIACEAEManu Chaudhary, Anurag PayasiDNA gyrase, a type II topoisomerase catalyzes the supercoiling of relaxed closed circular DNA. In this report we evaluated the in vitro inhibitory effect of non antibiotic adjuvant compounds disodium edetate and sodium citrate against supercoiling activity of bacterial DNA gyrase. Further, we assessed the effect of different drugs alone and in combination with one or more adjuvants in overcoming … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 8 Feb 2014 · 7,288 accessesView PDFCite
Research ArticleOpen accessIn the abstractSOFT COMPUTING BASED MEDICAL IMAGE RETRIEVAL USING SHAPE AND TEXTURE FEATURESM. Mary Helta Daisy, S. Tamil SelviImage retrieval is a challenging and important research applications like digital libraries and medical image databases. Content-based image retrieval is useful in retrieving images from database based on the feature vector generated with the help of the image features. In this study, we present image retrieval based on the genetic algorithm. The shape feature and morphological based texture features are … …American Journal of Applied Sciences, Vol. 11, Issue 2 · 24 Dec 2013 · 6,579 accessesView PDFCite
Research ArticleOpen accessIn the abstractCONSTRAINT INFORMATIVE RULES FOR GENETIC ALGORITHM-BASED WEB PAGE RECOMMENDATION SYSTEMS. Prince Mary, E. BaburajTo predict the users navigation using web usage mining is the primary motto of the web page recommendation. Currently, researchers are trying to develop a web page recommendation using pattern mining technique. Here, we propose a technique for web page recommendation using genetic algorithm. It consists of three phases as data preparation, mining of informative rules and recommendation. The data … …Journal of Computer Science, Vol. 9, Issue 11 · 5 Oct 2013 · 6,670 accessesView PDFCite
Research ArticleOpen accessIn the abstractStudy on Survival of Chlamydia trachomatis in the Presence of Antichlamydial DrugsApurb Rashmi Bhengraj, Pragya Srivastava, Harsh Vardhan et al.Problem statement: Recurrent genital Chlamydia trachomatis infections due to treatment failures may results in complex sequelae leading to reproductive complexity and morbidity. It can be resulted by the heterotypic resistance with decreased drug susceptibility characteristic of the isolate. Studies are needed to understand the treatment failures and resistance characteristic of C. trachomatis. Hence, in vitro study was conducted on C. … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 20 Feb 2012 · 7,768 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Genetic Algorithm Based Multi Objective Service Restoration in Distribution SystemsSathish Kumar Kannaiah, Jayabarathi Thangavel, D. P. KothariProblem statement: A Genetic Algorithm (GA) used here to find exact or approximate solutions to optimization and search problems. Genetic algorithms are a particular class of evolutionary algorithms that use techniques inspired by evolutionary biology such as inheritance, mutation, selection and crossover. Approach: GA is a method for search and optimization based on the process of natural selection and evolution. … …Journal of Computer Science, Vol. 7, Issue 3 · 9 Mar 2011 · 7,029 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Optimization of Design for S4-Duty Induction Motor Using Constraints Normalization Based Violation TechniqueR. Subramanian, S. N. Sivanandam, C. VimalaraniProblem statement: Design of Induction motors is an engineering art and needs an extensive experience for obtaining an optimal design solution for a given design problem. An optimized GD2 value for the development of S4 Duty, cage induction motor to meet the specifications of a particular designated application (the location of application is kept as trade secret due to IP … …Journal of Computer Science, Vol. 6, Issue 2 · 28 Feb 2010 · 7,057 accessesView PDFCite
Research ArticleOpen accessIn the abstractHyper-Ag-specific Ab Production in NC/Nga Mice is not associated with Deletion Polymorphism in the Promotor Region of the FcγRIIB GeneTohru Sakai, Mariko Nakamoto, Emi SutoProblem statement: NC/Nga (NC) mice produced high levels of ovalbumin (OVA)-specific IgG, IgG1 and IgG2a. We previously found deletion polymorphisms in the promoter region of fcgr2b in NC mice. To determine whether this mutation causes a hyper-humoral immune response, we generated congenic BALB/c mice carrying the NC-type fcgr2b allele (NC fcgr2b) and analyzed humoral immune response and FcγRIIB on germinal … …American Journal of Immunology, Vol. 5, Issue 3 · 31 Dec 2009 · 7,364 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Porcine Mitochondrial Transcription Factor a Gene: Molecular Characterization, Radiation Hybrid Mapping and Genetic Diversity among 12 Pig BreedsTanja Kunej, Xiao-Lin Wu, Jennifer J. Michal et al.Problem statement: Mitochondrial transcription factor A (TFAM) is a nucleus-encoded protein that is a key activator of mitochondrial transcription as well as a major participant in mitochondrial genome replication. Genomic characterization of the porcine TFAM gene is, therefore, necessary to determine its involvement in regulation of fat depots and meat quality traits in pigs. Approach: Genomic DNA sequence was determined … …American Journal of Animal and Veterinary Sciences, Vol. 4, Issue 4 · 31 Dec 2009 · 6,870 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Improved Genetic Algorithm Based on Adaptive Repair Operator for Solving the Knapsack ProblemSunanda Gupta, M. L. GargProblem statement: Knapsack problem is a typical NP complete problem. During last few decades, Knapsack problem has been studied through different approaches, according to the theoretical development of combinatorial optimization. Approach: In this study, modified evolutionary algorithm was presented for 0/1 knapsack problem. Results: A new objective_func_evaluation operator was proposed which employed adaptive repair function named as repair and elitism … …Journal of Computer Science, Vol. 5, Issue 8 · 31 Aug 2009 · 7,713 accessesView PDFCite