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Research ArticleOpen accessIn the abstractEffects of a Cyclachaena Xanthiifolia Extract on Trematodes Opisthorchis Felineus: An in Vitro StudyDenis Ponomarev, Elena Khramova, Natalia Gubanova et al.Cyclachaena xanthiifolia is a phytochemically rich invasive weed with documented allelopathic properties, making it a candidate source of bioactive compounds with potential medicinal applications. This study investigated the anthelmintic activity of a crude aqueous-ethanolic extract of C. xanthiifolia (CxEt), prepared from equal proportions of leaves and seeds, against the trematode Opisthorchis felineus in vitro. The effects of CxEt on the … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 1 Jun 2026 · 1,253 accessesView PDFCite
Literature ReviewOpen accessIn the abstractIntracranial Atherosclerotic Disease: Treatment Potential and Diagnostic OpportunitiesAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Anton Yuvenalievich Postnov et al.Atherosclerosis, characterized by the accumulation of atherosclerotic plaques within large arteries, substantially increases the risk of cardiovascular events, including ischemic stroke. Intracranial atherosclerotic disease (ICAD) represents a particularly significant clinical threat given its strong association with ischemic stroke across multiple intracranial arterial territories. This review provides a comprehensive analysis of the pathogenesis, diagnosis, and management of intracranial atherosclerosis. Special attention … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 5 May 2026 · 1,096 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessing the Comparative Effectiveness of Ensemble CatBoost Versus XGBoost Models in Predicting Heart Disease OutcomesManivannan D., G. Gifta Jerith, G. Chandra Sekhar et al.Cardiovascular Diseases (CVDs) are a common form of heart disease that remains a significant global cause of mortality, responsible for more than 30% of all fatalities. Without intervention, the global fatality count is projected to reach 22 million by 2030. Arterial plaque buildup may impede blood flow, potentially causing heart attacks or strokes. A combination of risk causes, including lack … …Journal of Computer Science, Vol. 22, Issue 4 · 4 May 2026 · 1,552 accessesView PDFCite
Review ArticleOpen accessIn the abstractDietary Flavonols With Antiviral Efficacy: Safety and Regulatory ConcernsTanisha Parvez, Tanveer Yaqub, Shama Parveen, Mohammad Khalid ParvezGlobally, a variety of pharmacologically-active plant or natural products are commonly consumed as health-protective dietary supplements. These are marketed as crude formulations, isolated metabolites, multi-vitamins, essential amino acids, unsaturated fatty acids and minerals. Of these, pharmacologically-active flavonols like rutin, quercetin, kaempferol, myricetin, isorhamnetin are the most consumed dietary supplements. In addition to their broad-spectrum therapeutic benefits, these are also known … …American Journal of Pharmacology and Toxicology, Vol. 20, Issue 1 · 19 Apr 2026 · 1,876 accessesView PDFCite
Review ArticleOpen accessIn the abstractRole of HDL in Atherogenesis: Cholesterol and AtheroprotectionAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Victor Yurievich Glanz et al.Atherosclerosis is a major global health burden, responsible for a significant proportion of cardiovascular morbidity and mortality worldwide. Its high prevalence and severe clinical consequences have made it a subject of extensive research. Despite considerable advances, the complexity of its pathogenesis continues to hinder the development of effective preventive strategies and therapeutic interventions. Current evidence implicates chronic inflammation, dysregulated lipid … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 3 Apr 2026 · 1,482 accessesView PDFCite
Research ArticleOpen accessIn the abstractTransfer Learning-Driven Binary Classification of Chest X-ray for Pneumonia Using Deep Convolutional ArchitecturesNusrath Fathima, Pradeep KumarPneumonia is the most common infectious cause of lung inflammation, resulting from the presence of viruses or bacteria in the microscopic air sacs. In recent years, artificial intelligence, particularly deep learning, has gained significant traction in the field of medical imaging. Early detection and diagnosis of pneumonia using chest X-rays can support radiologists in clinical decision-making and subsequent treatment planning, … …Journal of Computer Science, Vol. 22, Issue 3 · 10 Mar 2026 · 1,547 accessesView PDFCite
Review ArticleOpen accessIn the abstractMachine Learning Advancements for Lung Cancer Detection: An In-Depth Review and Future ProspectsAanchal Vij, Kuldeep Singh Kaswan, Anand NayyarLung cancer is a major cause of cancer-related mortality globally, underscoring the necessity for efficient diagnostic instruments. The review paper summarizes the role of ML and DL in detection, staging, and prognostication of lung cancer. We evaluate the relative efficacy of several models, such as CNNs, SVMs, and ensemble approaches, by analyzing publically accessible imaging and molecular information. We emphasize … …Journal of Computer Science, Vol. 22, Issue 1 · 1 Mar 2026 · 1,799 accessesView PDFCite
Research ArticleOpen accessIn the abstractDecoding Lung Cancer: PLAU as a Critical Driver and Diagnostic MarkerStanley Cho, Min Gyeong KimLung cancer remains a leading cause of cancer-related mortality, and understanding its underlying molecular mechanisms is critical for developing targeted therapies. We developed a novel tool called the Transcriptome-TCGA Integration (TTI), which combines in vitro transcriptome data with clinical datasets from the Cancer Genome Atlas (TCGA). TTI allows for the identification of key genes and pathways involved in lung cancer, … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,429 accessesView PDFCite
Literature ReviewOpen accessIn the abstractCorrelation of Atherosclerosis and Osteoarthritis, the Role of Inflammation in the Pathogenesis of Osteoarthritis and AtherosclerosisAnastasia V. Poznyak, Nikolay A. Orekhov, Aleksandra Sergeevna Utkina et al.Cardiovascular Diseases (CVD) rank among the leading causes of death globally, accounting for a substantial proportion of mortality rates and affecting millions of individuals. Risk factors such as ageing, obesity, diabetes and a sedentary lifestyle contribute significantly to the prevalence of CVD. Osteoarthritis (OA), on the other hand, is one of the most common joint disorders, affecting a large segment … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,777 accessesView PDFCite
Research ArticleOpen accessIn the abstractAuto Weight Dilated Convolutional Ensemble Network for the Severity Analysis of Lung Cancer in CT ImagesL. Sandhya, K. MarimuthuLung cancer is one of the world's leading causes of morbidity and mortality; improving patient outcomes requires an early and precise diagnosis. Lesion and tumor segmentation remains a challenging task in CT images due to their inherent imaging limitations, such as the small size of nodules, heterogeneous textures, blurry boundaries, and adjacent structures, leading to misclassification and difficulty in delineating … …Journal of Computer Science, Vol. 22, Issue 1 · 9 Feb 2026 · 1,550 accessesView PDFCite