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81 results for “lymphocyte”
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Research ArticleOpen accessIn the abstractActin Cytoskeleton and Related Proteins Role During Immune Cells Migration, Polarity and Activation: An OverviewClaudio Vieira da SilvaImmune cells migration, polarity and activation are essential during host immune response. Upon recognition of specific peptides presented by Human Leukocyte Antigen (HLA) molecules on Antigen Presenting Cells (APC), lymphocytes execute subset-related functions such as killing, help and regulation. These cells travel through the organism in a succession of steps, including entry into tissues, interstitial migration, APC scanning, synapse formation … …American Journal of Immunology, Vol. 9, Issue 4 · 19 Nov 2013 · 6,783 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Comparative Study of the Ovine Haemogram: Cell-Dyn 3500 Versus Manual MethodsLabrini V. Athanasiou, Constantinos G. Giannakopoulos, Zoe S. Polizopoulou et al.Manual hematology techniques traditionally applied in farm animal medicine are time consuming and labor-intensive, especially when large numbers of samples have to be processed. As a result, several automated hematology instruments have been developed for use in these species. An automated hematology analyzer (Abbott Cell-Dyne 3500 system) was used in performing a complete blood cell count and differential counts of … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 4 · 23 Oct 2013 · 7,183 accessesView PDFCite
Research ArticleOpen accessIn the abstractLike an Invertebrate Primitive AntibodyMichel LeclercSpecific immune responses occur in an invertebrate: The sea star Asterias rubens. Sea star T and B lymphocytes are present in the axial organ and coopere with phagocytes and Complement components to produce a primitive antibody correlated to Igkappa genes and to complement genes: It could be composed of 4 kappa chains and present strong and highly significant homologies to … …American Journal of Immunology, Vol. 9, Issue 3 · 20 Aug 2013 · 7,046 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvidence of Interleukin Genes in the Sea-Star: Asterias rubens (Echinoderma)Michel Leclerc, Patricia OttenThe axial organ of the sea star Asterias rubens is a primitive immune organ the sea star T lymphocytes, when stimulated by various lectins, produce lymphokin-like substances with mitogenic properties as shown in earlier studies; they are correlated with Interleukin genes. …American Journal of Immunology, Vol. 9, Issue 2 · 22 Jun 2013 · 7,283 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnamnestic Immune Response Eight Years After Immunization of Primates with a Multivalent HIV-1 GP120 Variable Peptide VaccineRebecca Rivera, Kyung Hee Kang, David E. Anderson et al.Successful development of an effective HIV vaccine hasn’t occurred yet partly as a consequence of the antigenic variation deployed by HIV-1 to escape the immune system. Our laboratory is dedicated to develop a single peptide synthesis approach to create multivalent peptides representing hypervariable epitopes of the gp120 envelope glycoprotein of HIV-1. Our previous study showed that our HIV HECs are … …American Journal of Immunology, Vol. 9, Issue 1 · 13 Mar 2013 · 7,212 accessesView PDFCite
Research ArticleOpen accessIn the abstractTargeting Cellular Receptors as a Strategy for the Development of New Generation Mucosal VaccinesConstantine Bitsaktsis, Kari Wiedinger, Edmund Joseph GosselinMucosal pathogens are a primary source of infection that require the development of vaccines to induce a specific, protective and long lasting immune response. Despite an urgent need, development of effective mucosal immunization strategies has proven difficult. The literature was reviewed to elucidate cell specific targets that may be utilized to increase the immunogenicity of protective antigens through mucosal vaccination. … …American Journal of Immunology, Vol. 9, Issue 1 · 2 Feb 2013 · 7,029 accessesView PDFCite
Research ArticleOpen accessIn the abstractCell-Mediated Immune Responses in the Sea-Star Asterias rubens (Echinoderm)Michel LeclercCell-mediated immune responses occur in sea star system. In Asterias rubens it is said that B sea star lymphocytes and T sea star lymphocytes exist in the axial organ which can be considered as an ancestral lymphoid organ. In the same manner the origin of lymphocytes can be found in Invertebrates such as Echinodermal. …American Journal of Immunology, Vol. 8, Issue 4 · 29 Nov 2012 · 7,254 accessesView PDFCite
Research ArticleOpen accessIn the abstractRendezvous with Tat: Transactivator of Transcription during Human Immunodeficiency Virus PathogenesisSneham Tiwari, Madhavan P.N. Nair, Shailendra K. SaxenaAcquired immune deficiency syndrome is a deadly disease caused by HIV, declared as a global catastrophe engulfing millions of lives per year. It took ~1.8 million lives in the year 2010 alone, as per reports of UNAIDS. HIV-1 is an enveloped retrovirus, having genome composed of two copies of ssRNA. It attacks the T-lymphocytes of the hosts, causes several multifaceted … …American Journal of Infectious Diseases, Vol. 8, Issue 2 · 31 Jul 2012 · 7,627 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Storing Temperature on Hepatotoxicity and Nephrotoxicity of Ifosfamide in Female RatFalah Mohammed AzizProblem statement: Ifosfamide (IFO) is a cytotoxic alkylating drug used for the treatment of a variety of cancers, although it has been found to induce certain hematological, hepatotoxic and nephrotoxic side effects. This drug is widely used in developing country, especially Iraq, but without caring too much to the storing temperature due to low drug maintaining facilities. The present work … …OnLine Journal of Biological Sciences, Vol. 12, Issue 1 · 19 Mar 2012 · 7,887 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Immunomodulatory Effect: Selection of the Correct Targets for Immunostimulation StudySwee Keong Yeap, Mashitoh Binti Abd Rahman, Noorjahan Banu Alitheen et al.Problem statement: Numerous plants or remedies that are traditionally used for various diseases had been claimed to maintain general good health, particularly the immune system. With the advanced understanding on immunology and ethnopharmacology, study on the interaction of this herb with the immune system is critical to understand the safety and its efficacy as a potent immunomodulatory agent. Approach: Selecting … …American Journal of Immunology, Vol. 7, Issue 2 · 4 Nov 2011 · 10,742 accessesView PDFCite