232 results for “Inhibition”

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Research ArticleOpen accessIn the abstractComputational Prediction of Diabetic Nephropathy-Associated Comorbidities and Their Key Genes by Analyzing RNA-Seq DataChaity Paul, Md. Ashiq Uddin, Rupa Dey et al.Diabetic Nephropathy (DN) is a complex health condition that leads to various kidney diseases. According to the World Health Organization, over 2 million deaths have been reported due to diabetes and diabetes related kidney diseases in 2021. And at the recent 78th World Health Assembly, chronic kidney disease was reported to be one of the most common diabetes-related complications, and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 19 May 2026 · 1,667 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPreparation and Properties Study of PCM@ECD BilayerYan Zhao, Heng Zhang, Yanfei Zhao et al.This study reports the fabrication of a core-shell active bilayer membrane (PCM@ECD) via a combined tape-casting and layer-transfer methodology. The inner core layer comprised Pectin-Chitosan (PC) microcapsules, synthesized by complex coacervation, encapsulating Orange Peel Essential Oil (OPEOM) with an embedding efficiency of 83.08%. The outer shell layer consisted of Ethyl Cellulose (EC) doped with zinc-doped carbon dots (Zn-CDs, average size: … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 8 May 2026 · 1,600 accessesView PDF Cite

Literature ReviewOpen accessIn the abstractUnraveling NETosis: From Immune Mechanisms to Therapeutic InnovationsAnastasia V. Poznyak, Alexey V. Churov, Gulalek Amanmyradovna Babayeva et al.Neutrophil Extracellular Traps (NETs) are integral to immune responses, serving both protective and pathological roles in inflammatory diseases. Despite increasing recognition of NETs, significant gaps remain in understanding the nuanced mechanisms of NETosis and its implications for health and disease. This review systematically explores NETosis—the formation of NETs—by elucidating the molecular signaling pathways and cellular mechanisms involved. We highlight the … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 21 Feb 2026 · 1,678 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPotentiometric Biosensor for Highly Toxic Pb (lead) and Cd (cadmium) Detection in Milk Using Layer-by-Layer ImmobilizationZhainagul Kakimova, Klara Zharykbasova, Aitbek Kakimov et al.Milk contamination with heavy metals such as lead (Pb) and Cadmium (Cd) poses a serious threat to public health, particularly in industrial regions. To address the need for rapid and on-site detection of these contaminants, a potentiometric biosensor was developed for the quantification of Pb²⁺ and Cd²⁺ ions in milk and dairy products. The biosensor functions by measuring the change … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 8 Feb 2026 · 1,480 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEvaluation of the Role of Galanin Hormone and Biochemical Markers in Individuals with Hair LossSheerin Farouq Shaker, Sarab Dalaf Khalaf, Omeed Akbar Ali, Shaimaa Tariq MahmoodHair loss is one of the problems that many people suffer from without knowing the real reason. Galanin is a neuropeptide closely involved in the modulation and inhibition of action potentials in neurons in the brain, spinal cord, and gut of humans. Therefore, we believe that it has a role in mineral absorption and hair loss. The aim of this … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 30 Jan 2026 · 1,928 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDihydroartemisinin Attenuates HBV-Induced Proliferation and Migration in LO2 cells via EMT Pathway ModulationYingde Nong, Caifang Ma, Wei Huang et al.Dihydroartemisinin (DHA), a derivative of artemisinin, possesses well-documented anti-inflammatory properties. This study investigated the inhibitory effects of DHA on hepatitis B virus (HBV)-induced cellular alterations in LO2 cells and elucidated underlying molecular mechanisms. Serum interleukin-6 (IL-6) levels were measured in HBV patients and analyzed for correlations with HBsAg, anti-HBs, and HBeAg. In vitro, LO2 cells were infected with clinical HBV … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 8 Jan 2026 · 2,071 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIn Vitro Antimicrobial Activity of Modified Lysozyme (Lys 90) and Herbal Extracts Against Multidrug-Resistant Escherichia coliEni Kusumaningtyas, Bagem BR Sembiring, Andriani et al.The emergence of Antimicrobial Resistant (AMR) poses a significant challenge to the poultry farming industry. This study investigated the potential of Lysozyme (Lys), modified Lysozyme (Lys 90), an herbal extract, and their combination (herbs + Lys 90) as alternative antimicrobial agents against Multidrug-Resistant Escherichia coli (MDR-E. coli). Lys 90 was prepared by heating Lys at 90 °C for 20 minutes. … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 1 Dec 2025 · 2,076 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAntibacterial Activity of Tali Bamboo (Gigantochloa apus) Leaf Extract to Inhibit Escherichia coli and Salmonella typhimuriumSinta Agustina, Komang Gede Wiryawan, Sri SuhartiBamboo leaves contain phytochemical compounds that have the potential to act as antimicrobial agents in inhibiting pathogenic bacteria. This study aimed to evaluate the potential of tali bamboo (Gigantochloa apus) leaves extracted with different solvents to inhibit the growth of Escherichia coli and Salmonella typhimurium. The tali bamboo leaves were extracted using ethanol and methanol with a ratio of 1:10 … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 3 · 25 Nov 2025 · 2,919 accessesView PDF Cite

Research ArticleOpen accessIn the abstractLarvicidal Activity of Spondias purpurea (Sineguelas) Leaf and Hylocereus costaricensis (Dragon Fruit) Stem Extracts Against Aedes aegyptiAlfredo V. Corpuz, Nigell Mikhail A. Gallardo, Ace Danielle C. AveroThe study determined the larvicidal activity of the different concentrations of Spondias purpurea and Hylocereus costaricensis extracts by measuring percent mortality in Aedes aegypti larvae, a primary vector of dengue and other arboviral diseases. The hypothesis proposed that combining both extracts would yield greater larvicidal activity due to potential synergistic interactions. Ethanolic extraction was used to isolate a wide array … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 20 Nov 2025 · 2,417 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDose-Dependent Neurotoxic Effects of Monosodium Glutamate and its Potential Genetic Transmission in MiceYanan Zou, Qiong Liang, Lu Liu et al.This study aimed to preliminarily investigated the neurotoxic effects of monosodium glutamate on mice and their pups, and the potential possibility of a genetic mechanism influencing the pups. In this study, mice were given different doses of Monosodium Glutamate (MSG) at doses of 2.0 or 4.0 g/kg body weight for 10 continuous days, and its impacts on both the mice … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 14 Nov 2025 · 3,031 accessesView PDF Cite