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Research ArticleOpen accessIn the keywordsLeukemia Inhibitory Factor (LIF) Gene Polymorphism and its Impact on Reproductive Traits of PigsM. A. Leonova, L. V. Getmantseva, V. N. Vasilenko et al.The purpose of this study was to determine the frequencies of alleles and genotypes of the Leukemia Inhibitory Factor (LIF) gene (ID: 399503) in Landrace, Large White and Duroc pigs in Russia and to evaluate the impact on productive traits of pigs. Polymorphism was genotyped using PCR-RFLP method. In the course of studies we observed a different distribution of allele … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 4 · 18 Oct 2015 · 7,406 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAssessment of Genetic Purity of Parental Lines of Hybrid Rice Using DNA-Based MarkersSunil Bhavsar, Twinkle Solanki, Suchita Amin, Neeru JainAssessment of hybrid seed genetic purity is one of the most important quality control parameters in hybrid seed production. With the objective of replacing the GOT with DNA based assays, Cytoplasmic Male Sterile (CMS), restorer and hybrid lines have been screened by means of microsatellite and Sequence Tagged Site (STS) markers. Cytoplasmic Male Sterile (CMS) lines often get contaminated with … …OnLine Journal of Biological Sciences, Vol. 15, Issue 2 · 13 Jun 2015 · 7,442 accessesView PDFCite
Research ArticleOpen accessIn the keywordsINTERVENTION OF PHARMACOGENETIC PROFILING IN THERAPEUTICS OF KASHMIRI POPULATION, A LESSON LEARNED FROM CYP3A5*3 VARIANTAshaqullah Bhat, Aadil Wani, Rajinder Kaur et al.Human Cytochrome P450 3A, a variant of Cytochrome P-450- dependent monooxygenases is a major drug metabolizing enzyme. CYP3A has evolved to catalyze the biotransformation of its substrate. A great deal of inter-individual variation in expression levels exists for CYP3A5 gene. The common polymorphism in CYP3A5 that induces a cryptic splice site has been shown to cause a significant reduction in … …OnLine Journal of Biological Sciences, Vol. 14, Issue 3 · 10 Jul 2014 · 7,218 accessesView PDFCite
Research ArticleOpen accessIn the keywordsQUERCETIN AMELIORATES DIABETIC NEPHROPATHY IN RATS VIA MODULATION OF RENAL NA+, K+-ATPASE EXPRESSION AND OXIDATIVE STRESSSalah O. Bashir, Mohamed Darwesh Morsy, Hussein F. Sakr et al.Diabetic Nephropathy (DN) is one of most prevalent complications of Diabetes Mellitus (DM), therefore prevention of its development is a important field for researches. Quercetin is a plant flavenoid with hypoglycemic and antioxidant properties that is claimed to have a reno-protective effect in diabetes. This study was designed to investigate the reno-preventive role of Quercetin treatment in terms of biochemical … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 14 Feb 2014 · 8,053 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCASE REPORT OF A PATIENT WITH RARE P.ARG136CYS (APOE2*) MUTATION IN APOLIPOPROTEIN E GENEJana Lisyova, Jan Chandoga, Stanislav Oravec et al.Apolipoprotein E (apoE) is a polymorphic glycoprotein associated with plasma lipoproteins and plays an essential role in the metabolism and clearance of plasma lipids. ApoE can represent the major genetic risk factor in development of premature atherosclerosis, coronary heart disease and late-onset familial and sporadic Alzheimer’s Disease (AD). We present a case report of a 51-year old male with suspected … …OnLine Journal of Biological Sciences, Vol. 14, Issue 1 · 9 Jan 2014 · 7,297 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHerpetic Viral RetinitisHidetaka NomaHuman Herpes Virus (HHV) is a DNA virus and is the most important viral pathogen causing intraocular inflammation. HHV is classified into types 1-8. Among these types, HHV-1, HHV-2, HHV-3 Varicella Zoster Virus (VZV) and HHV-5 Cytomegalovirus (CMV) are known to cause herpetic viral retinitis, including acute retinal necrosis and CMV retinitis. Herpes viral retinitis can be diagnosed from characteristic … …Current Research in Virology, Vol. 2, Issue 1 · 29 Jul 2013 · 12,795 accessesView PDFCite
Research ArticleOpen accessIn the keywordsISOLATION AND CHARACTERIZATION OF HELICOBACTER PYLORI STRAINS FROM GASTRIC BIOPSIES OF ALGERIAN PATIENTSGuetarni Hassina, Bensoltane AhmedThe objective of this study is to isolate and characterize strains Helicobacetr pylori from gastric biopsies by upper gastrointestinal endoscopy. After a rapid urease test, two Helicobacter pylori strains isolated from four patients on blood agar. After extraction of DNA from these strains from homogenates of gastric biopsies, quantification by real-time PCR was performed to determine Helicobacter pylori on the … …OnLine Journal of Biological Sciences, Vol. 13, Issue 2 · 19 Apr 2013 · 7,266 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHepatitis B Virus DNA Can be Amplified Directly From Dried Blood Spot on Filter PaperNaglaa Fathy Alhusseini, Mamdouh Z. Abadeer, Sheref M. El-TaherHepatitis B Virus (HBV) infections represent a major public health problem because of the ability of HBV to cause a chronic carrier state. Even though chronic carriers remain largely asymptomatic, a large number of these individuals subsequently develop cirrhosis and primary hepatocellular carcinomas. Dried Blood Spot (DBS) samples are a simple and inexpensive sampling method, especially useful for blood collection … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 8,461 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRole of Progranulin Gene Expression as a Molecular Biomarker for Bladder CancerSalwa M. Abo El-khair, Mie A. Mohamed, Tamer E. AlkhiaryBladder cancer is the second most common cancer of the urinary system. Early diagnosis of this tumor and estimation of risk of future progression has a significant impact on prognosis. Although there are several molecular markers for the diagnosis and prognosis for this tumor, their accuracy is not ideal. Progranulin is a growth factor that may play a critical role … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 7,701 accessesView PDFCite
Research ArticleOpen accessIn the keywordsGanoderma Species Associated with Basal Stem Rot Disease of Oil PalmLing-Chie Wong, Choon-Fah J. Bong, A. S. IdrisProblem statement: Basal Stem Rot disease (BSR) is one of the most serious diseases that have been causing major losses in the oil palm industry in Southeast Asia, especially in Malaysia and Indonesia. Several species of Ganoderma have been reported pathogenic to oil palm, however, the diversity and differentiation of the Ganoderma species were not widely studied and the identity … …American Journal of Applied Sciences, Vol. 9, Issue 6 · 19 Mar 2012 · 9,638 accessesView PDFCite