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149 results for “Metabolism”
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Research ArticleOpen accessIn the abstractVirtual Screening of Bioactive Compounds from the Onion (Allium) Genus as Potential Epidermal Growth Factor Receptor Inhibitors for MonkeypoxDinda Ratu Agustiani, Rakhmat Ramdhani Alwie, Harry NoviardiMonkeypox (Mpox) is an emerging zoonotic disease caused by the Mpox virus infection that affects humans and animals. Epidermal Growth Factor Receptor (EGFR) is an important target in the pathogenesis of Mpox. Epidermal Growth Factor (EGF), encoded by orthopoxviruses, plays an important role in intercellular transmission of the virus. Onion is known to have antiviral and immunomodulatory properties. Active compounds … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 6 Aug 2026 · 945 accessesView PDFCite
Research ArticleOpen accessIn the abstractMRI Observation and Analysis of Muscle Activity During ExerciseLi-Chang Zou, Hong-Wu LiWhile conventional biomechanical testing techniques are able to determine the mechanical characteristics of muscle tissue, they do not offer precise insight into how muscle metabolism and microstructure change in response to various types of exercise activities over the course of time. Using Magnetic Resonance Imaging (MRI) analysis of muscle tissue allows researchers to examine how different levels of intensity affect … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 30 Jul 2026 · 1,025 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Phytobiotic Carica Papaya Seed Extract on Growth Performance, Physiological Parameters, Gastrointestinal and Immune Organs of BroilersNovi Mayasari, Erna Ainal Mardiah, Selly Masella et al.Papaya (Carica papaya) seeds (PS) are known as a potential phytobiotic alternative to Antibiotic Growth Promotor (AGP) in poultry. Papaya seed extract (PSE) contains bioactive compounds such as carpine, chymopapain, and papain. Two hundred one-day-old Cobb strain broiler chicks were randomly allocated to five dietary treatments with four replicates per treatment, and each replicate consisted of ten birds. During the … …American Journal of Animal and Veterinary Sciences, Vol. 21, Issue 1 · 13 Apr 2026 · 1,900 accessesView PDFCite
Literature ReviewOpen accessIn the abstractCorrelation of Atherosclerosis and Osteoarthritis, the Role of Inflammation in the Pathogenesis of Osteoarthritis and AtherosclerosisAnastasia V. Poznyak, Nikolay A. Orekhov, Aleksandra Sergeevna Utkina et al.Cardiovascular Diseases (CVD) rank among the leading causes of death globally, accounting for a substantial proportion of mortality rates and affecting millions of individuals. Risk factors such as ageing, obesity, diabetes and a sedentary lifestyle contribute significantly to the prevalence of CVD. Osteoarthritis (OA), on the other hand, is one of the most common joint disorders, affecting a large segment … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,769 accessesView PDFCite
Research ArticleOpen accessIn the abstractUnveiling the Potential of Dombeya buettneri K.Schum As a Drug Agent: Molecular Docking of Compounds With Enzymes Linked to Diabetes and Neurodegenerative DiseaseEsther Emem Nwanna, Samuel Chima Ugbaja et al.This study investigated the mechanisms of Dombeya buettneri (snowball leafy) extracts on diabetes, hypertension, and neurodegenerative diseases. It compared extracts obtained using steep water (a by-product of corn wet milling) and aqueous water. The extracts were analyzed for total phenol, total flavonoid content, antioxidant activities such as FRAP, ABTS, NO, DPPH, iron-induced lipid peroxidation assay, degradation of deoxyribose (Fenton’s reaction), … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 1 Feb 2026 · 2,025 accessesView PDFCite
Literature ReviewOpen accessIn the abstractRumen Microbiota Mysteries: Nutrition, Function, and its Impact on Livestock ProductivityHamdi Mayulu, Marry ChristiyantoRuminants are important herbivores in the global food system, serving as primary producers of meat and milk. The productivity of these animals is influenced by the functionality of their digestive organs, namely rumen. The digestion, metabolism and nutrients absorption in the rumen epithelium enhance the host defende mechanisms mechanisms, promoting health and productivity in ruminants. Therefore, this review aimed to … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 2 · 4 Aug 2025 · 4,069 accessesView PDFCite
Research ArticleOpen accessIn the abstractRandom Forest-Based Genome Analysis for Disease Association and SNP Marker IdentificationXiangdong LiuAt present, genomic data analysis has the problems of insufficient model interpretation and limited computational efficiency in disease association research. As a powerful machine learning algorithm, Random Forest has demonstrated excellent ability in processing complex and multi-dimensional data sets and has gradually become a popular tool in the field of bioinformatics. The purpose of this paper is to explore how … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Jul 2025 · 5,533 accessesView PDFCite
Research ArticleOpen accessIn the abstractExploring the Role of Vitamin B12 as an Anti-atherogenic and Anti-inflammatory Agent in Apparently Healthy Adults With Hypovitaminosis DShravan Ajith Panchwadkar, Sudha Kuthethur, Sowndarya Kollampare, Neelam Manjunath PawarVitamin B12 deficiency is associated with metabolic changes like methyl malonic acidemia and hyperhomocystinemia eventually leading to atherosclerosis. Dyslipidemia and vitamin D (vit D) deficiency are independent risk factors of CVD. This study aims to explore the interrelationship between inflammatory markers, adverse lipid profile and vitamin B12 in hypovitaminosis D. Since, atherosclerosis is an inflammatory condition we have investigated CRP … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 11 Jul 2025 · 3,326 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiosynthesis and Evaluation of Zinc, Copper, and Methionine Feed Supplements Using Saccharomyces cerevisiae on Duck Performance in Minimal Water SystemsHendi Setiyatwan, Muhammad Rifqi IsmirajOptimizing duck performance under minimal water conditions is essential for sustainable poultry farming. Biosynthesizing essential feed supplements like Zinc (Zn), Copper (Cu), and methionine using Saccharomyces cerevisiae presents a promising method to enhance growth and meat quality. This study developed a biosynthesis method for Zn, Cu, and methionine supplements using S. cerevisiae and evaluated their effects on duck performance. In … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 1 · 11 Feb 2025 · 4,405 accessesView PDFCite
Research ArticleOpen accessIn the abstractGadolinium at Low Concentration Suppresses both Osteoclastic and Osteoblastic Activities in the Scales of GoldfishNobuo Suzuki, Kazuki Watanabe, Aika Sekimoto et al.For determining the effect of environmental pollutants on fish bone metabolism, we have developed an in vitro bioassay system using teleost scales that has osteoclasts, osteoblasts and bone matrix as markers: alkaline phosphatase (ALP) for osteoblasts and tartrate-resistant acid phosphatase (TRAP) for osteoclasts. Using this bioassay, the influence of gadolinium (Gd) on osteoclasts and osteoblasts of goldfish scales was examined … …American Journal of Environmental Sciences, Vol. 15, Issue 4 · 20 Sep 2019 · 8,451 accessesView PDFCite