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132 results for “In silico”

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Research ArticleOpen accessEvery word in the titleIn Silico Characterization and Motif Election of Neurotoxins from Snake VenomMahmudul Hasan, Ziaul Faruque Joy, Elius Hossain Bhuiyan, Md Shiful IslamSnake venom is a mixture of many biological components. Snakes usually use their venomic armory to tackle different prey and predators in adverse natural world. Among various components of the snake venom, neurotoxins play an important role in exerting effect by blocking the neuromuscular transmission through selective binding to muscle nicotinic Acetyl-Choline Receptors (nAChR). A set of 30 reference protein … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 2 · 2 Mar 2015 · 7,706 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIN SILICO DESIGN OF THE M2 PROTON CHANNEL INHIBITORS OF H1N1 VIRUSUsman Sumo Friend Tambunan, Mochamad Reza Rahdiansyah, Arli Aditya ParikesitM2 proton channel of H1N1 Influenza A virus is the target protein anti-flu drugs amantadine and rimantadine. However, the two once powerful adamantane-based drugs lost their 90% bioactivity because of mutations of virus in recent twenty years. The resistance of influenza A virus to amantadine need to develop more effective adamantane-based drugs. Several research by molecular docking method have been … …OnLine Journal of Biological Sciences, Vol. 13, Issue 1 · 5 Jan 2013 · 8,002 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleFabrication and Tensile Property Analysis of Polymer Matrix Composites of Graphite and Silicon Carbide as FillersVikram G. Kamble, Naveen Kumar L.In a world there is ever-increasing demand for new materials, composite materials finds the topmost spot. Here in this work an attempt has been made to study the mechanical properties of Glass and Vinyl Ester composites with and without fillers. Laminates are prepared by Hand Layup technique with changing the volume percentage of Vinyl Ester and fillers in each. The … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 1 · 3 Dec 2015 · 8,037 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSynthesis of Nanoparticles of Mixed Oxides Containing Titanium Cerium Silver and Silicon: Phase TransformationAkkarat Wongkaew, Waree Jansome, Supachai Khemchan et al.Problem statement: Titanium dioxide is a well known material using with self-cleaning application. This is due to its properties after exposed to UV light: Superhydrophilicity and photocatalysis. The addition of other oxides could prolong these properties without continuing exposed to UV. However, titanium dioxide phase is essential. In order to obtain these properties, titanium dioxide needs to be in anatase … …Energy Research Journal, Vol. 1, Issue 2 · 31 Oct 2010 · 7,826 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleResidual Defects in Silicon Implanted with Boron and Phosphorous IonsM. JadanAccumulation of radiation defects in Si implanted with B+ or P+ ions, and formation of the residual extended defects (dislocation loops, rod-like defects) in the process of successive thermal treatment have been studied. The anomalies observed in the formation of the extended defects are associated with the elastic stresses in the damaged regions affecting the process of radiation defects clustering. …American Journal of Applied Sciences, Vol. 2, Issue 4 · 30 Apr 2005 · 6,935 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSemen Quality and Artificial Insemination Efficacy Using Sericin-Silica-Phosphate-CuO Hydrogel in Thin-tailed SheepEnike Dwi Kusumawati, I Wayan Karyasa, Duran Corebima Aloysius et al.Artificial Insemination (AI) in livestock is increasingly demanded because it greatly affects the productivity and quality of livestock. AI should be supported by advanced material chemistry, especially organic-inorganic hybrid biomaterials. We aimed to produce a prototype of renewable advanced biomaterial technology in the form of Sericin-Silica-Phosphate (SER-SI-PO) hydrogel reinforced with Copper Nanoparticles (CuNPs) and its application in AI. The testing … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 2 · 10 Jun 2025 · 3,855 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIdentification of Pharmacological Targets Combining Docking and Molecular Dynamics SimulationsIlizaliturri-Flores Ian, Rosas-Trigueros Jorge Luis, Carrillo-Vazquez Jonathan Pablo et al.Studies that include both experimental data and computational simulations (in silico) have increased in number because the techniques are complementary. In silico methodologies are currently an essential component of drug design; moreover, identification and optimization of the best ligand based on the structures of biomolecules are common scientific challenges. Geometric structural properties of biomolecules explain their behavior and interactions and … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 1 · 21 Mar 2013 · 8,130 accessesView PDFCite
Research ArticleOpen accessIn the keywordsReduction of Radiation Effects in Biomedical Imaging Detectors by Technology ChangeEssesse Songa Auguste, Wembe Tafo Evariste, Madinatou Salomon, Belinga Aboudou JeanSilicon is a preferred material in the design of medical imaging detectors. It enables reliable and inexpensive detectors to be produced. However, the operation of this material is compromised when irradiated with high radiation of more than 5 ×1014 particles/cm2of high energy neutrons. The defects caused transform the electrical properties. Therefore, this loss of information compromises the reconstruction of important … …American Journal of Engineering and Applied Sciences, Vol. 14, Issue 3 · 17 Jul 2021 · 6,995 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBootstrap Approach to Correlation Analysis of Two Mineral ComponentsT.O. OlatayoProblem statement: In this article we considered pairs bootstrap through a truncated geometric bootstrap method for stationary time series data. Construction of valid inferential procedures through the estimates of standard error, coefficient of variation and other measures of statistical precision such as bootstrap confidence interval were considered. The method was used to confirm the correlation between Silicon Oxide (SiO2) and … …Current Research in Geoscience, Vol. 2, Issue 1 · 7 May 2013 · 6,597 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffect of Low Temperature on the Fabrication of Microring Resonator by Wet EtchingHazura Haroon, Sahbudin Shaari, P. Susthitha Menon et al.Research related to semiconductor devices often relies on wafer fabrication. The fabrication of Silicon (Si) based devices by anisotropic wet etching can be affected by many etching parameters such as etching temperature, crystal orientation and percent of composition. Most of the anisotropic wet etchings by KOH solution done before were conducted at temperature over 70°C. We found that the temperatures … …American Journal of Applied Sciences, Vol. 9, Issue 12 · 7 Nov 2012 · 7,131 accessesView PDFCite