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197 results for “oxidative”
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Research ArticleOpen accessEvery word in the titleQUERCETIN AMELIORATES DIABETIC NEPHROPATHY IN RATS VIA MODULATION OF RENAL NA+, K+-ATPASE EXPRESSION AND OXIDATIVE STRESSSalah O. Bashir, Mohamed Darwesh Morsy, Hussein F. Sakr et al.Diabetic Nephropathy (DN) is one of most prevalent complications of Diabetes Mellitus (DM), therefore prevention of its development is a important field for researches. Quercetin is a plant flavenoid with hypoglycemic and antioxidant properties that is claimed to have a reno-protective effect in diabetes. This study was designed to investigate the reno-preventive role of Quercetin treatment in terms of biochemical … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 14 Feb 2014 · 8,053 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Virgin Olive Oil (Olea europea. L) on Kidney Function Impairment and Oxidative Stress Induced by Mercuric Chloride in RatsYoucef Necib, Ahlem Bahi, Sakina Zerizer et al.The study was designed to investigate the possible protective role of virgin olive oil in mercuric chloride induced renal stress, by using biochemical approaches. The effects of virgin olive oil on mercuric chloride induced oxidative and renal stress were evaluated by serum creatinine, urea and uric acid levels, kidney tissue lipid peroxidation, GSH levels, GSH-Px and GST activities. Administration of … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 16,791 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDetecting Patterns in 5’ Untranslated Regions of Genes Involved in the Regulation of Blood Pressure and Oxidative StressMaria Sanchez-Aguilar, Luz Ibarra-Lara, Beatriz Zamora-Lopez et al.Hypertension is a chronic physical condition with multifactorial causes. Although genetic factors have been associated to this pathological condition, characterization of the sequence patterns in the regulatory sites, for example, in 3’ or 5’ Untranslated Regions (UTR), remains to be explored. In particular, the 5’ UTR of genes associated with the regulation of blood pressure and oxidative stress are analyzed … …Current Research in Medicine, Vol. 4, Issue 2 · 27 Nov 2013 · 7,285 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBiomarkers of Oxidative DNA Damage and Soluble Fas/Fas Ligand in Type 2 Diabetic PatientsMohamed H. Mahfouz, Ibrahim A. Emara, Ghada A. OmarProblem statement: Involvement of oxidative stress in the pathogenesis of diabetic complications has been proposed. 8-hydroxy-2'-deoxyguanosine (8-OHdG) has been reported to serve as a new sensitive biomarker of the oxidative DNA damage in vivo. Apoptosis via Fas/Fas Ligand (FasL) interactions has been proposed to be a major T-cell-mediated effector mechanism in autoimmune diabetes. This study was undertaken to investigate whether … …American Journal of Applied Sciences, Vol. 9, Issue 4 · 3 Feb 2012 · 7,110 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvidence of Oxidative Stress in Autism Derived from Animal ModelsXue Ming, Michelle A. Cheh, Carrie L. Yochum et al.Autism is a pervasive neurodevelopmental disorder that leads to deficits in social interaction, communication and restricted, repetitive motor movements. Autism is a highly heritable disorder, however, there is mounting evidence to suggest that toxicant-induced oxidative stress may play a role. The focus of this article will be to review our animal model of autism and discuss our evidence that oxidative … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,121 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThree Mild Stresses Known to Increase Longevity in Drosophila melanogaster Flies do not Increase Resistance to Oxidative StressÉric Le BourgExposure to a mild stress at a young age (hypergravity, cold or heat) increases longevity and resistance to heat shocks in Drosophila melanogaster flies and it may also delay behavioral aging and increase resistance to other stresses. The effect of these mild stresses on resistance to oxidative stress has not been studied. Flies were thus fed on a saccharose solution … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,304 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn-Vivo Evaluation of Hexavalent Chromium Induced DNA Damage by Alkaline Comet Assay and Oxidative Stress in Catla catlaKantha Deivi Arunachalam, Sathesh Kumar Annamalai, Jaya Krishna KuruvaIn the present study, the acute toxicity of Chromium in fingerlings of Catla catla, an Indian major carp, was evaluated with renewal bioassay method. In vivo studies were designed to assess the extent of Micronucleus Assay, Comet Assay under the exposure of common heavy-metal compounds, namely, Chromium Nitrate, using Catla catla (2n = 20), as a test model. The laboratory … …American Journal of Environmental Sciences, Vol. 9, Issue 6 · 15 Jan 2014 · 7,200 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleButyrate Supplementation Affects Mrna Abundance of Genes Involved in Glycolysis, Oxidative Phosphorylation and Lipogenesis in the Rumen Epithelium of Holstein Dairy CowsAnne Hermen Laarman, Louis Dionissopoulos, Ousama AlZahal et al.Energy availability in epithelial cells is a crucial link for maintaining epithelial barrier integrity; energy depletion is linked to impaired barrier function in several epithelia. This study aimed to elucidate the effects of exogenous butyrate on mRNA abundance of genes indirectly involved in rumen epithelial barrier integrity. Sixteen mid-lactation Holstein cows fed a total mixed ration received a concentrate mix … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 4 · 27 Nov 2013 · 7,525 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAluminium-Induced Hepatotoxicity and the Protective Role of Withania somnifera (Ashwagandha) in Wistar RatsAnchana Babu, Rekha D Kini, Nayanatara Arun Kumar, Megha GokulAluminium is a widely distributed environmental contaminant whose chronic exposure leads to accumulation in multiple organs, including the liver, resulting in oxidative stress and tissue damage. When reactive oxygen species production exceeds the body's antioxidant defense capacity, cellular injury ensues — a mechanism central to aluminium-induced hepatotoxicity. Withania somnifera (Ashwagandha), an evergreen herb of the Solanaceae family widely cultivated in … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 6 Apr 2026 · 1,451 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDetermination of the Probiotic Potential and Metabolic Function of Lactobacillus Strains for Healthy Calf RearingRaya Myktybayeva, Serkan Özkaya, Elif Rabia Şanlı et al.This research investigstes the impact of probiotic supplementation on the growth performance, health status, and physiological traits in Holstein calves. A total of thirty calves were randomly divided into three experimental groups: a control group and two treatment groups receiving probiotics at doses of 1 g/10 kg and 1.5gt/10 kg live weight. Key indicators, including Live Weight (LW), Body Measurements … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 23 Jul 2025 · 3,635 accessesView PDFCite