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113 results for “influence function”
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EditorialOpen accessIn the abstractImpact of Quantitative Pharmacology on Drug DevelopmentAna Ruiz-Garcia, Kourosh ParivarThesuccess of drug development rests over two well defined pillars, a goodunderstanding of the drug’s clinical pharmacology and the appropriate targetpopulation for whom the clinical use is intended. The label for human prescription drugsrequires a good understanding of the pharmacological effects (pharmacodynamicsor PD) and the mechanism of action of the drug as well as detailed informationof the drug’s Pharmacokinetics (PK): … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 24 Apr 2015 · 7,158 accessesView PDFCite
Research ArticleOpen accessIn the abstractTHE TEMPORAL DYNAMICS OF REGIONAL CITY SIZE DISTRIBUTION: ANDHRA PRADESH (1951-2001)G. Kumar, A. SubbarayanSystems with measurable entities are characterized by certain properties of their size distribution. City Size Distribution (CSD) and the underlying city size dynamics have received attention in the urban economic literature in recent years. In this approach we aim at evaluating the temporal dynamics of city size distribution in Andhra Pradesh, an Indian state for the period 1951-2001. The research … …Journal of Mathematics and Statistics, Vol. 10, Issue 2 · 14 Apr 2014 · 6,815 accessesView PDFCite
Research ArticleOpen accessIn the abstractZinc Deficiency and Associated T-Cell Dysfunctioning among Human Immunodeficiency Virus SeropositivesM. Andrew Pradeep, M. Thiruvalluvan, V. Nalini, J. Stella MaryProblem statement: All the nutrients in the diet play a crucial role in maintaining an optimal immune response. In both, deficient and excessive intake of nutrients can have negative consequence on the immune status and susceptibility to a variety of pathogens. Zinc is an essential micronutrient for human growth development and immune function. It plays a vital role in structure … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 8,037 accessesView PDFCite
Research ArticleOpen accessIn the abstractSpatial-Functional Analysis of Kurdish Courtyard Houses in Erbil CityFaris Ali Mustafa, Ahmad Sanusi HassanProblem statement: This study was to analyze the concept of spatial-function in courtyard house layout and its influence to the cultural and social activities. Themes such as integration, segregation, accessibility and zoning of the building space layout are required to be deliberated, in order to achieve further understanding about the Kurdish social and cultural benchmarks (norms) that might have affected … …American Journal of Engineering and Applied Sciences, Vol. 3, Issue 3 · 30 Sep 2010 · 8,836 accessesView PDFCite
Research ArticleOpen accessIn the abstractVoltage-Gated Channels as Causative Agents for EpilepsiesMutasem Abuhamed, Xiao Bo, Kun Xia et al.Problem statement: Epilepsy is a common neurological disorder that afflicts 1-2% of the general population worldwide. It encompasses a variety of disorders with seizures. Approach: Idiopathic epilepsies were defined as a heterogeneous group of seizure disorders that show no underlying cause .Voltage-gated ion channels defect were recognized etiology of epilepsy in the central nervous system. The aim of this article … …American Journal of Immunology, Vol. 4, Issue 4 · 31 Dec 2008 · 6,959 accessesView PDFCite
Research ArticleOpen accessIn the abstractCross-Latitudinal, Seasonal and Diurnal Comparisons in Thyroid Hormone Concentrations in Sled DogsKriya L. Dunlap, Arleigh J. Reynolds, Kent R. Refsal et al.Problem Statement: Hypothyroidism has been a common disorder in humans and dogs. Amongst a sundry of functions, the thyroid gland plays a key role in metabolism and consequently, hypothyroidism has been a common diagnosis for a decrease in performance in sled dogs. Research has indicated that a variety of environmental factors influence thyroid hormone production, of which, light exposure, climate, … …American Journal of Animal and Veterinary Sciences, Vol. 3, Issue 4 · 31 Dec 2008 · 7,184 accessesView PDFCite
Research ArticleOpen accessIn the abstractChanges in Prothrombin Time and Platelet Parameters of Mice Treated with Vitamins C and EHongwei Li, Jing Cheng, Wei Wang et al.This study aims to elucidate the influence of supplementation with different doses of Vitamin C (VC) and Vitamin E (VE) on Prothrombin Time (PT) in mice; forty eight mice are randomly divided into six treatment groups, which are fed different dose VC and VE except for control Check (CK) for eight weeks. Blood samples are obtained from the mouse canthus … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 15 Apr 2020 · 7,087 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdsorption Behavior of Bone Morphogenetic Protein-2 on a Graphite Substrate for Biomedical ApplicationsIzabele Marquetti, Salil DesaiThe interaction of proteins with biomaterials plays an important role for several biomedical applications including implants and tissue engineering. Although different experimental approaches have been explored, the investigation of the molecular models for protein-substrate interaction is warranted to control of cellular functions. In this study, Molecular Dynamics (MD) simulations were used to study the adsorption behavior of Bone Morphogenetic Protein-2 … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 19 Jun 2018 · 8,705 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Non-Intrusive Experiment to Examine the Visual Attention Data on Exposure to a Brand Using Eye TrackingSurya Bahadur Thapa, Prasun Gahlot, Komal Suryavanshi et al.The objective of this study is to understand the influence of articulation on sports sponsorship posters of a sporting event. An eye tracking experiment was conducted to examine the visual attention data on exposure to the sponsor’s brand while viewing an advertisement poster. The respondents were asked to fill out a questionnaire based on what they could recall while viewing … …Journal of Computer Science, Vol. 19, Issue 3 · 28 Feb 2023 · 5,908 accessesView PDFCite
Research ArticleOpen accessIn the abstractCharacterization of the Changes in Opened Sufu Bottles During Storage with Mathematical ModelJingJing Liang, Dawei Li, Ruiqin Shi et al.Artificial Neural Network (ANN) is a type of nonlinear empirical model, which can clarify the complex relation between the inputs and outputs that allows it to approximate any nonlinear function for making predictions. The objective of this study is to monitor the Biogenic Amines (BAs) content and selected physicochemical properties of sufu (a traditional Chinese fermented soybean product) along time. … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 4 · 12 Dec 2018 · 9,353 accessesView PDFCite