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47 articles for “Promoter”
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Research ArticleOpen accessIn the abstractPDX-1 and MafA: Key Transcription Factors in PancreasHideaki Kaneto, Takeshi Miyatsuka, Yoshihisa Nakatani, Taka-aki MatsuokaPancreatic and duodenal homeobox factor-1 (PDX-1) plays a crucial role in pancreas development, β-cell differentiation and in maintaining normal β-cell function by regulating several β-cell-related genes including insulin. PDX-1 has potency to induce insulin-producing cells in non β-cells in various tissues such as pancreas and liver and PDX-1-VP16 fusion protein more efficiently induces insulin-producing cells, especially in the presence of … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 7,389 accessesView PDFCite
Research ArticleOpen accessIn the abstractColor Doppler Evaluation of Isovolumetric Relaxation Time and of Signals Arising from Axons of the Median Nerve as a Means to Evaluate Mitochondrial Functionality in the Context of Immunotherapy of Cancer and Chronic Conditions Associated with Mitochondrial DysfunctionStefania Pacini, Marco RuggieroReactive Oxygen Species (ROS) arising from the disruption of mitochondrial respiration act as endogenous mutagens and tumor promoters. When production of ROS exceeds the capacity of DNA repair mechanisms, random mutations and aneuploidy ensue, thousands of genes become unbalanced and genetic/epigenetic chain reactions lead to progressive aneuploidy with only two outcomes: karyotypes so altered that are not viable or karyotypes … …American Journal of Immunology, Vol. 15, Issue 1 · 12 Oct 2019 · 9,690 accessesView PDFCite
Research ArticleOpen accessIn the abstractGilsonite Modified Asphalt for Use in Pavement ConstructionAliasghar Akbari Nasrekani, Mostafa Nakhaei, Koorosh Naderi et al.Properties such as durability and moisture resistance of asphalt concrete significantly improve pavement service life. When siliceous aggregate is used, then preventing moisture damage and stripping become distinctly required. Typically, stripping could be prevented by either using antistripping agents or by modifying the binders. The anti-stripping agent achieve its purpose by changing the aggregates' affinity for water through changing the … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 3 Apr 2018 · 9,380 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Dietary Supplementation with Pumpkin oil (Cucurbita pepo) on Performance and Blood Fat of Broiler Chickens during Finisher PeriodHosna Hajati, Ahmad Hasanabadi, Park W. WaldroupProblem statement: Using most of antibiotic growth promoters as feed additives has been banned by the European Union due to cross-resistance against pathogens and residues in tissues; and scientists search for alternatives to antibiotics, two days. In this view, medicinal plants and essential oils extracted are becoming more important due to their antimicrobial and stimulating effects on animal digestive systems. … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 1 · 26 Apr 2011 · 9,724 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic and Biochemical Aspects of Ectoine Biosynthesis in Moderately Halophilic and Halotolerant Methylotrophic BacteriaValentina N. Khmelenina, Ildar I. Mustakhimov, Alexander S. Reshetnikov et al.Problem statement: The cyclic imino acid ectoine is a widely distributed compatible solute synthesizing by halophilic and halotolerant bacteria to prevent osmotic stress at high external salinity. This water-keeping compound is used in a variety of commercial cosmetics and therapeutic products. Approach: Development of integrated, predictive functional model of the metabolic and regulatory netwoks of ectoine-producing microbes is an active … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 4 · 13 Dec 2010 · 9,560 accessesView PDFCite
Research ArticleOpen accessIn the abstractInhibition of U6 snRNA Transcription by PTENStephanie Cabarcas, Kounosuke Watabe, Laura SchrammProblem statement: RNA polymerase III (RNA pol III) is responsible for transcribing many of the small structural RNA molecules involved in RNA processing and protein translation, thereby regulating the growth rate of a cell. RNA pol III transcribes both gene internal (tRNA) and gene external (U6 snRNA) promoters and proper initiation by RNA polymerase III requires the transcription initiation factor … …OnLine Journal of Biological Sciences, Vol. 10, Issue 3 · 30 Sep 2010 · 8,551 accessesView PDFCite
Research ArticleOpen accessIn the abstractOrganic Alternative for Breaking Dormancy in Table Grapes Grown in Hot RegionsConsuelo Corrales-Maldonado, Miguel Angel Martinez-Tellez, Alfonso A. Gardea et al.Problem statement: In warm-winter regions, the need for intervention of chemical means to break bud rest becomes a dominant factor for maintaining economic production of table grapes. However, the problem is more acute when farmers want to grow organic table grapes in the absence of environmentally-friendly budbreak promoters. Approach: This study aimed to evaluate the effect of a mix of … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 2 · 30 Jun 2010 · 8,753 accessesView PDFCite