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139 results for “Immune response”
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Review ArticleOpen accessIn the keywordsImmunodiagnosis in Jembrana Disease: A ReviewAsmarani Kusumawati, Tenri Ashari Wanahari, Widya Asmara et al.Jembrana disease is a bovine disease that affects Bali cattle (Bos javanicus). The causal agent is named Jembrana Disease Virus (JDV), a lentivirus member. The disease development of Jembrana disease in Bali cattle is unique for a lentivirus infection as it is related with severe clinical syndrome in an acute period. In experimentally JDV-infected Bali cattle, the death rate was … …American Journal of Immunology, Vol. 11, Issue 3 · 21 Oct 2015 · 7,657 accessesView PDFCite
Research ArticleOpen accessIn the abstractProduction of an Achillea millefolium (Yarrow) Toothpaste to Combat Gum and Tooth PainMunashe K. F. Chakamanga, Ashley Kumalo K, Dirk Hamadziripi MGum inflammation also known as gingivitis is primarily caused by the accumulation of dental plaque that forms on teeth. The inflammation triggers pain in the gums and surrounding tissues due to increased blood flow and immune activity aimed at combating the bacterial infection. Thus, this study was carried out to investigate the efficacy of Yarrow-based toothpaste in reducing gum inflammation. … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 9 Oct 2026 · 440 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunomodulatory and Antioxidant Effects of Stachys Japonica Miq. Ethanol Extract on Cyclophosphamide-Induced Immunosuppressed Mice and its Phytochemical CompositionXueping Jiang, Jianglong He, Yanjun Chen, Fang WangStachys japonica Miq. is an edible wild botanical drug and a traditional medicine in China. This study focused on examining the phytochemical profile and antioxidant properties of the ethanol extract of S. japonica Miq (SJEE) in vitro, as well as its immunomodulatory and antioxidant activities in cyclophosphamide (Cy)-induced immunosuppressed mice. The SJEE was analysed by UPLC-HRMS/MS. 36 Polyphenols, including flavonoids, … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 13 Apr 2026 · 1,456 accessesView PDFCite
Literature ReviewOpen accessIn the abstractUnraveling NETosis: From Immune Mechanisms to Therapeutic InnovationsAnastasia V. Poznyak, Alexey V. Churov, Gulalek Amanmyradovna Babayeva et al.Neutrophil Extracellular Traps (NETs) are integral to immune responses, serving both protective and pathological roles in inflammatory diseases. Despite increasing recognition of NETs, significant gaps remain in understanding the nuanced mechanisms of NETosis and its implications for health and disease. This review systematically explores NETosis—the formation of NETs—by elucidating the molecular signaling pathways and cellular mechanisms involved. We highlight the … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 21 Feb 2026 · 1,685 accessesView PDFCite
Research ArticleOpen accessIn the abstractPredicting Antigenic Peptides Using a Multi-Level Transformer Model with Enhanced Feature SelectionAshwini S., Minu R. I., Jeevan KumarThis Antigenic Peptide (APs) prediction is one of the most important roles to improve vaccine design and interpret immune responses. This paper develops a Multi-Level Pooling-based Transformer model, which improves the accuracy and efficiency of predicting T-cell epitopes. The model utilizes peptide sequences from the Immune Epitope Database, employing a refined Kolaskar and Tongaonkar algorithm for feature extraction and a … …Journal of Computer Science, Vol. 21, Issue 7 · 17 Jul 2025 · 3,451 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Effect of Main Heat Shock Proteins on AtherosclerosisAnastasia Vladimirovna Poznyak, Alexey V. Churov et al.Atherosclerosis is a multifaceted disease characterized by complex pathogenesis involving diverse mechanisms. In recent years, the autoimmune nature of atherosclerosis has gained significant attention, emphasizing the indispensable role of the immune system in its initiation and progression. Heat Shock Proteins (HSPs) are vital for cellular functionality, facilitating cellular adaptation to environmental changes and survival under adverse conditions. Notably, various HSP … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 3 Oct 2024 · 4,361 accessesView PDFCite
Review ArticleOpen accessIn the abstractCirculating Immune Complexes as an Important Link between Inflammation and Lipid Alterations in AtherosclerosisAnastasia Vladimirovna Poznyak, Nikolay Alexandrovich Orekhov, Vasily Nikolaevich Sukhorukov et al.This review article rigorously investigates the emerging facets of atherosclerosis pathogenesis through an exhaustive examination of the existing data on the intricate interplay between lipid metabolism disorders and inflammation. A primary objective of this study is to thoroughly explore the role of Circulating Immune Complexes (CIC) as a pivotal indicator of this multifaceted interaction. The focus of this review centers … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 14 Aug 2024 · 3,932 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 13,008 accessesView PDFCite