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113 results for “vaccine”
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Review ArticleOpen accessEvery word in the titleHost Receptor Immunomodulation in Response to Shigella Surface Antigens: An Insight for Vaccine DevelopmentAshim K. Bagchi, Rushita A. Bagchi, Dipak K. Hens et al.Shigellosis, caused by Shigella is the most common cause of bacillary dysentery. The disease is associated with high morbidity and mortality rate owing to its multiple drug resistance. Hence recovery from the disease would primarily depend on the development of an effective immune-modulator for strong mucosal immune response. The role of cellular immunity may be a critical factor in protection … …American Journal of Immunology, Vol. 11, Issue 2 · 21 Jun 2015 · 6,755 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePrevalence of Oncogenic HPV Types in Sardinia (Italy): Implications for the Impact of Prophylactic Anti-HPV VaccinesStefania Montisci, Sabrina Pitzalis, Marianna Greco et al.Infection with high-risk HPV genotypes is considered an essential step in cervical carcinogenesis. Recently, prophylactic anti-HPV vaccines have shown to provide effective protection in clinical trials. However, protection appears to be type-restricted, thus, its real extent will depend on HPV types prevalence in the target population. Here we report HPV prevalence in 555 Italian women with various stages of HPV-related … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 7,040 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMolecular-Biological Properties of the Attenuated Strain of Salmonella Abortus-Equi E-841, used in the Creation of a Vaccine against Abortion of MaresAssiya Mussayeva, Natalya Yegorova, Merey Yerishov et al.Salmonella abortion of mares takes a leading place in the in factious pathology of horses and leads to the abortion of pregnant mares and infected stallions become salmonella carriers. The disease with salmonella abortion manifests itself in the last months of pregnancy, maybe-during the mass foal of mares-in the spring. The article results obtained of studies on the biological properties … …American Journal of Animal and Veterinary Sciences, Vol. 16, Issue 2 · 28 May 2021 · 7,125 accessesView PDFCite
Research ArticleOpen accessIn the keywordsProduction of Immunologically Active Untagged Recombinant DENV-2 NS1 in Escherichia coliDessy Natalia, Christian Heryakusuma, Fernita Puspasari et al.Dengue is an infectious disease affecting 390 millions people in tropical and subtropical region annually. Dengue virus NS1 protein plays an important role in viral replication in the host cell and it is detected in high level in the infected patient serum. A synthetic gene of untagged DENV-2 NS1 with codons optimization for expression in Escherichia coli has been generated … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 3 · 10 Oct 2018 · 10,348 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEconomic Evaluation of Streptococcus Pneumoniae Culture MediaVictor Morais, Norma SuárezStreptococcus pneumoniae, a major bacterial pathogen worldwide, requires a complex medium for culture, which complicates harvesting of antigens for vaccine production. Here we present an economic evaluation of factors affecting the production cost of a chemically defined medium for the scale up of fermentation of S. pneumoniae, compared with the most traditional fermentation media. A basic laboratory-scale experiment of 1 … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 2 · 27 May 2016 · 8,379 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSDS-PAGE Protein Pattern and Antigenicity Cross Reaction of Human SchistosomesNahed A.A. EL-Ossily, Doaa A. Yones, Mohamed El-Salahy M.M. Monib et al.Schistosomiasis is one of the most important neglected tropical diseases. Its control depends on treatment with the available drug praziquantel. No vaccine exists despite the intense search for molecular candidates and adjuvant formulations over the last three decades. The present study aimed to compare the antigenic protein structures of Schistosoma mansoni, S. haematobium, Fasciola. hepatica and Echinococus granulosus hydatid cyst … …American Journal of Infectious Diseases, Vol. 12, Issue 1 · 10 Feb 2016 · 7,360 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMicrobial Translocation and B Cell Dysfunction in Human Immunodeficiency Virus DiseaseWei JiangThe gut mucosal barrier disrupted in HIV disease, resulting in increased systemic exposure to microbial products such as Lipo Polys Accharide (LPS). The association of enhanced microbial translocation and B cell dysfunction in HIV disease is not fully understood. High dose and short term exposure of microbial Toll-Like Receptor (TLR) agonists were used as vaccine adjuvants, however, low dose and … …American Journal of Immunology, Vol. 8, Issue 2 · 30 Jun 2012 · 7,413 accessesView PDFCite
Research ArticleOpen accessIn the keywordsImmunity to Diphtheria in Haemodialysis PatientsAbdolreza Sotoodeh Jahromi, Mortaza Pourahmd, Sara Azhdari et al.Problem statement: The incidence of infectious diseases is increased in patients with chronic renal failure. Chronic renal failure severely influences the immune functions of the host. Diphtheria is of great epidemiological concern. Although mainly observed during childhood, unvaccinated adults and relatively immunocompromised patients are at increased risk for acquiring diphtheria. Approach: To evaluate the anti-Diphtheria immunity level in southern Iranian … …American Journal of Infectious Diseases, Vol. 7, Issue 1 · 27 Jun 2011 · 8,097 accessesView PDFCite
Research ArticleOpen accessIn the keywordsFormulation and Evaluation of a Novel Needle-Free Hepatitis B Surface Antigen Delivery SystemC. D. Licy, K. Premalatha, Annie Shirwaikar, Arun ShirwaikarProblem statement: Hepatitis B is a major public health problem, killing 1-2 million people annually, despite the introduction of an effective vaccine in 1982. Approximately 400 million persons worldwide have chronic hepatitis B. This is due to problems associated with vaccine delivery, stability and cost. Hence the present challenge in Vaccinology is to develop safer, cheaper and easy-to-deliver forms of … …Current Research in Medicine, Vol. 1, Issue 2 · 30 Oct 2010 · 6,821 accessesView PDFCite
Research ArticleOpen accessIn the keywordsReactive Nitrogen Intermediates Production by Macrophages of Mycobacterium bovis-Infected Goats and Supplemented with Dyhidroxyvitamin D3 in vivoAurora Martinez-Romero, Jose Luis Ortega-Sanchez, Jose Ramon Hernandez-Salgado et al.Problem statement: Tuberculosis (TB) remains one of the world's major health problems. To evaluate in vivo indices of cellular sensitization, antigen-induced Reactive Nitrogen Intermediates (RNI) responses by blood mononuclear cells from Mycobacterium bovis BCG-infected goats supplemented with 1, 25 dyhidroxyvitamin D3 [1, 25-(OH)2D3]. Approach: An experimental, longitudinal and comparative study was planned. Twelve animals of goat cattle 20-to 24-month-old sannen … …American Journal of Animal and Veterinary Sciences, Vol. 4, Issue 1 · 31 Mar 2009 · 7,617 accessesView PDFCite