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116 articles for “Response Surface”

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Research ArticleOpen accessIn the keywordsOptimization and Molecular Identification of Protease-Producing Thermophilic Bacterial Isolate TUA-26Anthoni Agustien, Mufidhatul Muqarramah, Feskaharny AlamsjahProtease enzymes are used as biocatalysts that can accelerate a reaction. Thermostable enzymes produced by thermophilic bacteria are needed in the industrial field because of their ability to withstand high temperatures. The thermophilic bacterial isolate TUA-26 that produces protease was to analyze the optimum conditions of temperature, pH, agitation, trace elements, carbon sources, and nitrogen sources; the stability of protease … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 6 Apr 2024 · 4,935 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOptimization of Preparation Procedures of Phlorizin-Zn (Ⅱ) Complex and Its Antioxidant Activity Study in vitroYuqing Zhang, Yaping Li, Guorui Yang et al.Flavonoid metal complexes possess more effective antioxidant properties than flavonoids. However, the preparation of the phlorizin-Zn (Ⅱ) complex and its antioxidant activity has not been reported. In this research, the preparation procedures of the phlorizin-Zn (Ⅱ) complex were enhanced using by single factor test and Response Surface Methodology (RSM). The optimal preparation procedures of the phlorizin-Zn (II) complex were as … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 3 Apr 2024 · 4,758 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSystematic Optimization of Ganoderma lucidum Polysaccharide Fermentation: A Guidance for IndustrializationBin Yang, Junhu Kai, Dehui Dai et al.Ganoderma Lucidum Polysaccharide (GLP) is one of the main active components of G. lucidum and a promising prebiotic for various diseases. Maximizing the production of GLP and minimizing the cost is important for the widespread use of GLP in the food/feed and pharmaceutical industries. The purpose of the present study was to optimize the fermentation condition of a single G. … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 30 Jan 2024 · 5,737 accessesView PDFCite
Research ArticleOpen accessIn the keywordsExtraction Process Optimization and Functional Characteristics of by Papain Solubilized Collagen from Large Yellow Croaker (Pseudosciaena crocea) SkinBiaoshi Wang, Wenfeng Li, Shumin Liu et al.Through collagen extraction from large yellow croaker (Pseudosciaena crocea) skin using an enzymatic method, the extraction optimization and characterization of collagen from raw materials after papain hydrolysis pretreatment are studied. The extraction process was optimized using the response surface methodology in this study. The findings show that the optimal conditions are a ratio (solvent to solid) of 25.0 mL/g, a … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 26 Dec 2023 · 5,553 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Efficiency of Seven-Variable Box-Behnken Experimental Design with Varying Center Runs on Full and Reduced Model TypesMary Paschal Iwundu, Joan CosmosResponse Surface Methodology is widely used in the optimization of industrial processes and products that depend on several experimental variables. One of the most tested and efficient second-order Response Surface Methodology designs is the Box-Behnken Design. This research explores the efficiency of a seven-variable Box-Behnken design with varying center runs, on full and reduced quadratic models. Backward Elimination and Forward … …Journal of Mathematics and Statistics, Vol. 18, Issue 1 · 8 Dec 2022 · 7,089 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPreparation and Quality Analysis of Pineapple Red Orange Fresh BeerJuan Yang, Biaoshi Wang, Xiaojun Hu et al.To optimize the brewing technology of pineapple red orange fresh beer, a single-factor experimental design was used to investigate the effects of fermentation sugar content, fermentation pressure and fermentation temperature. Based on the single-factor test results, the Box-Behnken test design and response surface analysis were used to optimize the process parameters with the sensory evaluation score as the response index. … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 5 Dec 2022 · 5,368 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPhytochemical Profiles and Anti-Diabetic Potential of the Extract of Pueraria lobata Compound Teabags: Preparation and Optimization Infusion ConditionsQing Liu, Wenyue Shi, Futing Xue et al.A Pueraria lobata root compound teabag using Pueraria lobate root, Stigma maydis, and Prunus mume as the main material was prepared in this study, and the brewing technology was optimized using Response Surface Methodology (RSM). The sensory evaluation, total polysaccharide, and phenolic compound content were used as evaluation indicators and the effect of the compound ratio of raw material was … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 26 Nov 2022 · 5,641 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOptimization of Purification Technology and Antioxidant Activity of Total Flavonoids from Sea Buckthorn LeavesJiale Shan, Yang Liu, Pu Zhao et al.China is rich in sea buckthorn (Hippophae rhamnoides L.)resources and a large amount of sea buckthorn fruit is used to extract oil andjuice every year. However, Sea Buckthorn Leaves (SBL), which are full offlavonoids, are discarded as waste. To make full use of resources and turn waste into valuables, theoptimal purification process of flavonoids from SBL was studied and theantioxidant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 3 · 27 Aug 2022 · 6,073 accessesView PDFCite
Research ArticleOpen accessIn the keywordsProducing Functional Fatty Acid DHA from Corn Steep Liquor by Aurantiochytrium SW1Xiaojie Ren, Qi Yan, Baoyue Liu et al.Thraustochytrium has a relatively high lipid content in the cell and its lipid content can account up to 70% of the dry cell weight. It is an important raw material for the third-generation biodiesel production and the production of functional fatty acid Docosahexaenoic Acid (DHA). However, the high cost of traditional fermentation medium has hindered the industrial production of lipid. … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 20 Nov 2021 · 6,323 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHydroxyl Radical-Scavenging Activity-Guided Extraction of Peptides from Oviductus ranaeJieyang Shen, Yihui Liu, Jiahao Xu et al.Oviductus Ranae (OR) is a traditional Chinese medicinal material that is listed in Chinese Pharmacopeia with proteins the most abundant ingredients. In present work, pepsin/trypsin-based stepwise hydrolysis was applied to extract Antioxidant Peptides from OR (APOR) using hydroxyl radical-scavenging capacity as evaluation index. After single-factor experiment, response surface method coupled with Box-Behnken design were used for optimizing process parameters and … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 18 Oct 2021 · 6,609 accessesView PDFCite