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242 articles for “Events”
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Review ArticleOpen accessIn the abstractJAK Inhibitors for Rheumatoid Arthritis: Assessing Efficacy and Safety in TreatmentAnastasia V. Poznyak, Varvara A Orekhova, Natalia Vladimirovna Elizova et al.Rheumatoid Arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation, progressive joint destruction, and systemic complications. Dysregulated cytokine signaling through the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway plays a central role in RA pathogenesis, making JAK inhibitors an important therapeutic option. Tofacitinib, baricitinib, and upadacitinib are oral targeted synthetic disease-modifying antirheumatic drugs that interfere with … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 8 Oct 2026 · 430 accessesView PDFCite
Research ArticleOpen accessIn the abstractAlternative Monitoring Approach for IPTVAngel Ignatov, Hristo Toshkov Hristov, Jan Latal et al.IPTV emerged in the late 1990s as a solution for delivering Video on Demand (VoD) and live television over managed networks. Its widespread adoption accelerated after the expansion of broadband internet and the introduction of web technologies such as HTML5 and adaptive streaming protocols (MPEG-DASH and HLS), which enabled television content to be streamed directly through web browsers. Across Europe, … …Journal of Computer Science, Vol. 22, Issue 11 · 8 Oct 2026 · 438 accessesView PDFCite
Literature ReviewOpen accessIn the abstractMolecular Genetic Basis of Starch Biosynthesis and Waxy Allelic Variation in Rice Grain QualityInnabat Sartbayeva, Aigul Amirova, Dana Mynbaeva et al.The culinary, nutritional, and industrial properties of rice (Oryza sativa L.) grains are fundamentally governed by the structural arrangement of endosperm starch, a complex physiological phenotype shaped by genetic architecture and environmental conditions. This review provides a comprehensive synthesis of the molecular pathways driving starch biosynthesis in rice, centering on allelic diversity within the Waxy (Wx) locus, which codes for … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 22 Sep 2026 · 487 accessesView PDFCite
Literature ReviewOpen accessIn the abstractIntracranial Atherosclerotic Disease: Treatment Potential and Diagnostic OpportunitiesAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Anton Yuvenalievich Postnov et al.Atherosclerosis, characterized by the accumulation of atherosclerotic plaques within large arteries, substantially increases the risk of cardiovascular events, including ischemic stroke. Intracranial atherosclerotic disease (ICAD) represents a particularly significant clinical threat given its strong association with ischemic stroke across multiple intracranial arterial territories. This review provides a comprehensive analysis of the pathogenesis, diagnosis, and management of intracranial atherosclerosis. Special attention … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 5 May 2026 · 1,096 accessesView PDFCite
Research ArticleOpen accessIn the abstractBridging Innovation and Access: Randomized, Single-Dose, Open-Label, Parallel-Group Bioequivalence Study of Generic and Innovator Injection Semaglutide in IndiaMayur Madhav Mayabhate, Nitin Kapure, Akhilesh Sharma, Radhakrishna VaddemSemaglutide, a long-acting Glucagon-Like Peptide-1 (GLP-1) receptor agonist, is effective in improving glycemic control, reducing body weight, and lowering cardiovascular risk in Type 2 Diabetes Mellitus (T2DM). Limited accessibility of the innovator formulation underscores the need for bioequivalent generic alternatives. To assess the pharmacokinetic bioequivalence of a synthetic Semaglutide Injection (2 mg/1.5 mL) developed by Alkem Laboratories Ltd., India, compared … …American Journal of Pharmacology and Toxicology, Vol. 20, Issue 1 · 20 Apr 2026 · 2,637 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Novel Time-Based Switch Migration Method (TSSM) for Load Balancing in Distributed Software-Defined NetworkingThangaraj E, Dinesh K, Prabhakaran Paulraj et al.Switch migration is predominantly used for workload balancing in distributed Software Defined Network (SDN) controllers. The Time-Sharing Switch Migration (TSSM) technique allowed the switch's responsibility to be divided based on the time duration condition of overload, which resulted in fewer overload events, fewer ping-pong controller issues, and more efficient controllers. However, it has higher controller resource utilization during TSSM working … …Journal of Computer Science, Vol. 22, Issue 3 · 6 Mar 2026 · 1,591 accessesView PDFCite
Research ArticleOpen accessIn the abstractCRISP-DM-Based Mobile Application for Predicting High-Crime Areas in Metropolitan LimaHugo Vega Huerta, Javier Vilca Velasquez, Nicolas Anicama Espinoza et al.The city of Lima, Peru, has been facing a serious climate of citizen security that has risen extremely high in recent years. The objective of this work is to identify and predict areas of high crime incidence through a mobile application based on historical data on criminal incidents recorded by users. The mobile application has been implemented using the CRISP-DM … …Journal of Computer Science, Vol. 22, Issue 2 · 27 Feb 2026 · 1,978 accessesView PDFCite
Literature ReviewOpen accessIn the abstractUnraveling NETosis: From Immune Mechanisms to Therapeutic InnovationsAnastasia V. Poznyak, Alexey V. Churov, Gulalek Amanmyradovna Babayeva et al.Neutrophil Extracellular Traps (NETs) are integral to immune responses, serving both protective and pathological roles in inflammatory diseases. Despite increasing recognition of NETs, significant gaps remain in understanding the nuanced mechanisms of NETosis and its implications for health and disease. This review systematically explores NETosis—the formation of NETs—by elucidating the molecular signaling pathways and cellular mechanisms involved. We highlight the … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 21 Feb 2026 · 1,685 accessesView PDFCite
Research ArticleOpen accessIn the abstractInternet of Things Based COVID-19 Patient in Self-Isolation Monitoring SystemBagaskara Akbar Fadhlillah, Ditdit Nugeraha UtamaSelf-isolation has become a critical measure for managing symptomatic or asymptomatic COVID-19 patients, particularly when healthcare facilities are overwhelmed. This study explores a monitoring system based on commercially available Wear OS smartwatches designed to track patient vital signs, specifically oxygen saturation (SpO₂), heart rate, and location, and generate alerts during atypical events. The research has two primary objectives, first, to … …Journal of Computer Science, Vol. 21, Issue 12 · 12 Feb 2026 · 1,293 accessesView PDFCite
Review ArticleOpen accessIn the abstractTheory and Strategies of Atherosclerotic Renal Artery Stenosis TreatmentAnastasia V. Poznyak, Nikolay A. Orekhov, Gulalek Amanmyradovna Babayeva et al.Atherosclerosis is a disease that affects large arteries and contributes to the development of cardiovascular disease and adverse events. The main characteristic of this disease is the formation of plaques that narrow the lumen of the vessel. However, atherosclerosis is not the only cause of vasoconstriction. For example, various causes may be involved in renal artery stenosis, such as vasculitis … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 4 Jan 2026 · 1,862 accessesView PDFCite