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419 results for “enzyme”
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Research ArticleOpen accessIn the abstractEffect of Phenylbutazone on Pentylenetetrazole-Induced Seizure in MiceKhayatnouri MirhadiProblem statement: The Cyclooxygenases (COXs), the key enzymes that convert arachidonic acid to Prostaglandins (PGs), had been implicated in physiological and pathophysiological functions in the CNS. Non-Stesoidal Anti-Inflammatory Drugs (NSAIDs), COX inhibitors, were used largely to treat febrile condition, pain state and for prevention of and therapeutics of many diseases. However the role of PGs and NSAIDs in the seizure … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 13 Dec 2011 · 7,675 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Effect of Enicostemma littorale Blume Methanolic Extract on Gentamicin-Induced Nephrotoxicity in RatsNiraj Mukundray Bhatt, Kinjal Chauhan, Sharad Gupta et al.Problem statement: The Amino glycoside antibiotics cause drug induced nephrotoxicity at therapeutic doses and thus limits the use clinically. Oxidative stress is one of the main reasons for the development of nephrotoxicity. Approach: In light of this the aim of the present study was to investigate the role of mitochondrial as well as post-mitochondrial oxidative stress in the development of … …American Journal of Infectious Diseases, Vol. 7, Issue 4 · 30 Nov 2011 · 9,547 accessesView PDFCite
Research ArticleOpen accessIn the abstractSlow Fungal Hydrolysis of Complex Sugar is Responsible for the Use of Sugar as Vehicle for Antifungal DrugsNedosa Ikenna Valentine, Utoh-Nedosa Uchechukwu Anastasia, Dan Danjuma et al.Problem statement: Aspergillus niger strain (UUF 9202) significantly reduced the dormancy period and boosted aggregate germination time in seeds of Tetrapleura tetraptera by 42% in 32 days and produced a net reduction in mean germination time of the seeds to 12 days. A structure-fungitoxicity relationship study of a series of isoflavonoids against Aspergillus niger and Cladosporium cucumerinum showed that a … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 3 · 2 Nov 2011 · 7,665 accessesView PDFCite
Research ArticleOpen accessIn the abstractExtra-Bone Marrow Sites of Haemopoeisis: Dihydroartemisinin Effects in Wistar Albino RatsNedosa Uchechukwu Anastasia, Saleh Mohammed, Nedosa Kenechi Stanislaus et al.Problem statement: Iron is present in ferritin, the storage form of iron in the tissues; in the respiratory cytochrome enzymes; in hemoglobin of the blood and in the myoglobin of muscle Dihydroartemisinin (DHA) has been shown to interact with heme groups in vivo and in vitro. This study investigated the effects of 5 day and 7day oral dihydroartemisinin treatments on … …American Journal of Applied Sciences, Vol. 9, Issue 1 · 2 Nov 2011 · 6,826 accessesView PDFCite
Research ArticleOpen accessIn the abstractMeat Spoilage Mechanisms and Preservation Techniques: A Critical ReviewD. Dave, Abdel E. GhalyProblem statement: Extremely perishable meat provides favorable growth condition for various microorganisms. Meat is also very much susceptible to spoilage due to chemical and enzymatic activities. The breakdown of fat, protein and carbohydrates of meat results in the development of off-odors, off-flavor and slim formation which make the meat objectionable for human consumption. It is, therefore, necessary to control meat … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 4 · 2 Nov 2011 · 54,798 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Cardioprotective Diet in Acute Coronary SyndromeR. B. Singh, Suniti Dharwadkar, Fabien DeMeester et al.Problem statement: Nutritional factors appear to be quite important in the pathogenesis and prognosis among patients of Acute Myocardial Infarction (AMI) or Acute Coronary Syndrome (ACS). Increased consumption of proinflammatory foods; such as refined starches and sugar, trans fat, saturated fat and w-6 fatty acids may increase proinflammatory cytokines, oxidative stress and free fatty acids causing endothelial dysfunction. Approach: Columbus … …Current Research in Medicine, Vol. 2, Issue 2 · 15 Oct 2011 · 7,460 accessesView PDFCite
Research ArticleOpen accessIn the abstractS-Allyl-Cysteines Reduce Amelioration of Aluminum Induced Toxicity in RatsSadhana ShrivastavaProblem statement: Aluminum (Al) is a trivalent cation found in its ionic form in most kinds of animal tissues and in natural waters everywhere. Approach: It is a potent neurotoxin and has been associated in the pathogenesis of several clinical disorders including Alzheimer’s disease. Results: The aim of the study was to demonstrate the protective effect of S-Allyl-Cysteines (SAC) against … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 12 Aug 2011 · 7,748 accessesView PDFCite
Research ArticleOpen accessIn the abstractTransesterification of Palm Oil for the Production of BiodieselKhalizani Khalid, Khalisanni KhalidProblem statement: Palm oil is known as an important source of edible oil with significant values of renewable energy. Depletion of petroleum had captured much attention on producing biodiesel from the palm oil. Approach: The most concerning methods for the production of biodiesel were discussed, namely transesterification (alkali and acid), enzymetic approach and supercritical alcohol. Results: The results showed the … …American Journal of Applied Sciences, Vol. 8, Issue 8 · 19 Jul 2011 · 8,389 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Vitamin A on Growth Performance, Antioxidant Status and Blood Constituents in Lactating Grey GoatWeiren Yang, Ping Wang, Yuanqiang Jing et al.Problem statement: It is regarded that vitamin A protects cells from damage by radicals which are believed to contribute to certain chronic diseases and regulates immune function of animals by protection of mucosal epithelium acting as the first defense barrier. All these properties of vitamin A may be attributable to its antioxidant activity. This study was to evaluate the effects … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 4 · 27 Dec 2010 · 7,674 accessesView PDFCite
Research ArticleOpen accessIn the abstractOligoglucans as Elicitors of an Enzymatic Antioxidant System in Zucchini Squash (Cucurbita pepo L.) Seedlings at Low TemperatureAbel Ceron-Garcia, Gustavo Adolfo Gonzalez-Aguilar, Irasema Vargas-Arispuro et al.Abstract: Problem statement: Non-controlled low temperatures affect physiological and biochemical processes leading to Reactive Oxygen Species (ROS) accumulation in plants, which normally are stabilized by the antioxidant system. Superoxide Dismutase (SOD), Ascorbate Peroxidase (APX) and Catalase (CAT) are the most important ROS-detoxification enzymes in stressed plants. Approach: The activity of these enzymes were examined in response to fungal Oligoglucans (OG) … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 1 · 15 Dec 2010 · 8,306 accessesView PDFCite