134 results for “toxic effect”

Set a search alert

Research ArticleOpen accessIn the abstractUse of Novel Triphenyltin (IV) Dithiocarbamate Compounds in Assessing the Cytotoxicity and Mode of Cell Death of Acute Lymphoblastic Leukemia Cell Lines, CCRF CEM (CCL-119)Normah Awang, Nur Hidayah Hasrin, Nurul Farahana Kamaludin et al.Chemotherapy and radiotherapy are often used to treat Acute Lymphoblastic Leukemia (ALL). However, the resistance problem of treatment using the current drug in ALL patients has decreased the effectiveness of such therapy. Therefore, a study needs to be conducted to identify the potential of new anticancer agents. Organotin (IV) dithiocarbamate, an organometallic compound, causes toxic effects on cancer cells in … …OnLine Journal of Biological Sciences, Vol. 23, Issue 2 · 10 Mar 2023 · 5,159 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAntiproliferative Potential of Pomegranate Peel Extract in MDA-MB Breast Cancer Cell LinesManal Asif Hamdulay, Fatema Yusuf Singaporewala, Grisilda Vidya Bernhardt et al.Nutraceuticals have gained recognition as adjuvant therapies in cancer treatment due to their non-toxic and protective properties. Among various natural products, pomegranate peel with high antioxidant capacity and rich polyphenol content suggest potential anticancer properties. Previous studies have shown promising anticancer effects of other parts of the pomegranate. The purpose of this research is to compare the effectiveness of Pomegranate … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 1 · 13 May 2025 · 5,582 accessesView PDF Cite

Review ArticleOpen accessIn the abstractA Review of Effects of Environmental Change on Human HealthUttam PaudelCurrent knowledge production on the effects of environmental exposures on human health reflects technological, social and economic development broadly; theoretical and methodological advancements in social science and medicine more specifically. Human health and the welfare mainly rely on refurbishing and protecting the integrity of the natural systems such as fresh air, safe water, biodiversity, toxic waste management and proper land … …American Journal of Environmental Sciences, Vol. 14, Issue 3 · 29 Apr 2018 · 8,538 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffect of Dietary Supplementation of a Mix of Chestnut and Quebracho Tannins on Intestinal Morphology, Bacterial Load, Eimeria spp oocyst Excretion and Immune Response after Vaccination in RabbitsFrancesca Parisi, Simone Mancini, Maurizio Mazzei et al.Among plant products, tannins exhibited a strong antioxidant activity and their employment was studied as food or feed addictive with positive effects. Nevertheless, their health-enhancing properties remain to be completely clarified, particularly in rabbits. The aim of the present study was to investigate the influence of a mix of chestnut and quebracho tannins as supplementation in rabbit diet on intestinal … …American Journal of Animal and Veterinary Sciences, Vol. 13, Issue 3 · 3 Aug 2018 · 8,619 accessesView PDF Cite

Case ReportOpen accessIn the abstractThe Diagnostic and Etiologic Challenge of Myocarditis in Oncologic Patients: Acute Myocarditis During Induction Treatment with All-Trans Retinoic AcidNúria Coma, Sergio Moral, Rosa Coll et al.Myocarditis is an inflammatory disease of the myocardium characterized by myocardial infiltration with inflammatory cells and non-ischemic myocytic necrosis. Its diagnosis is based on clinical, electrocardiogram, laboratory and echocardiographic parameters and also cardiac magnetic resonance or endomyocardial biopsy when possible. It occurs primarily as a result of infections that include viruses, parasites, bacteria and fungi. Moreover, there are other causes … …American Journal of Infectious Diseases, Vol. 17, Issue 3 · 7 Jun 2021 · 7,013 accessesView PDF Cite

Review ArticleOpen accessIn the abstractUse of Entomopathogenic Fungi as Biopesticides to Manage Insect Pest: A ReviewAnthony Emaru, Jane Gesimba Nyaanga, Saidi MwanarusiEntomopathogenic Fungi (EPF) biopesticides are more environmentally friendly and are an alternative to toxic synthetic chemicals. Due to EPF's pathogenic nature to various arthropod pests, it is thus considered a primary candidate for an integrated biological approach due to its numerous invaluable effects. However, an urgent need is to develop an environmentally safer, more sustainable, and practical approach to managing … …American Journal of Applied Sciences, Vol. 21, Issue 1 · 12 Jul 2024 · 8,015 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEvaluation of the Renoprotective Effects of Valsartan in Methotrexate-Induced Acute Kidney Injury in RatsDina KutbiMethotrexate (MTX) is a widely used chemotherapeutic agent known for its nephrotoxic effects, which can lead to acute kidney injury in hospitalized patients. However, the mechanism by which MTX induces nephrotoxicity is not entirely clear, but it is believed to involve oxidative stress and direct toxic effects on renal tubules. Valsartan, an angiotensin II receptor blocker, has been shown to … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 4 May 2024 · 4,571 accessesView PDF Cite

Review ArticleOpen accessIn the abstractThe Exposure of Pesticides to Honeybees: A Global Threat to Food SecurityHalima Sadia, Pratik Raj Karki, Mansura Afroz et al.The pivotal role of honeybees as global pollinators underscores their significance in ecological and agricultural systems. However, the beekeeping industry faces a significant challenge due to the improper utilization of pesticides, resulting in adverse effects on honeybee populations. This comprehensive review endeavors to investigate the toxicity of pesticides to honeybees, examining the various routes of exposure. Furthermore, it aims to … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 20 Jan 2024 · 6,058 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Toxic Spectrum of Ricinus Communisand Zingiber Officinalis Essential Oils against Musca Domestica L.Hanan Abo El-Kassem BoslyThe housefly, Musca domestica L., is a cosmopolitan insect, associated with various diseases and is one of the species with the greatest ability to develop resistance to insecticides. The study designed to evaluate the larvicidal, pupicidal, adulticidal and ovicidal effect of lethal concentrations LC50 of R. communis and Z. officinalis essential oils against the housefly M. domestica L. The larvicidal … …American Journal of Agricultural and Biological Sciences, Vol. 12, Issue 4 · 2 Dec 2017 · 8,311 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffect of Heavy Metals on the Enzymatic Activity of Haplic Chernozem under Model Experimental ConditionsNatalia Gromakova, Saglara Mandzhieva, Tatiana Minkina et al.The biological activity of soils is an essential parameter of their ecological status. The anthropogenic Heavy Metals (HMs) disturb the normal functioning of soil biota and, hence, the entire soil system. The aim of this work was to estimate the toxicity of loosely bound HM compounds in Haplic Chernozem using parameters of cellulose-degrading and urease activities. Contamination of Haplic Chernozem … …OnLine Journal of Biological Sciences, Vol. 17, Issue 3 · 23 Jul 2017 · 7,994 accessesView PDF Cite