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Research ArticleOpen accessIn the abstractPunicalagin Suppresses Mediators Involved in Labor Onset and Progression in vitroCaitlyn Nguyen-Ngo, Jane C Willcox, Martha LappasSpontaneous preterm birth is the leading cause of neonatal morbidity and mortality. Inflammation plays a central role in the activation of myometrial contractions and rupture of fetal membranes associated with spontaneous preterm birth. The pomegranate polyphenol punicalagin is known to possess anti-inflammatory properties. In this study, we aimed to determine the effect of punicalagin on pro-inflammatory and pro-labor mediators in … …American Journal of Immunology, Vol. 17, Issue 1 · 22 Dec 2021 · 7,609 accessesView PDFCite
Research ArticleOpen accessIn the abstractDoes Iron Modulate Cytokine Production by Desferrioxamine Treated Mononuclear Cells?Hanna Bessler, Meir DjaldettiIron is an essential element for maintaining the normal function of cellular and multicellular organisms and it is closely associated with inflammation and immunity. Macrophages and lymphocytes play an important role in its homeostasis. Hereby we have evaluated cytokine production by iron depleted and iron supplemented human peripheral blood mononuclear cells (PBMC) from healthy adult donors. Non-stimulated or stimulated PBMC … …OnLine Journal of Biological Sciences, Vol. 18, Issue 1 · 7 Jan 2018 · 6,845 accessesView PDFCite
Research ArticleOpen accessIn the abstractPhytoremediation and Adsorption of Heavy Industry Emitted from Cement Industry through Plant Leaves, Case Study: Golestan Peivand Cement FactorySoleyman Ghorbanzadeh, Meysam Madadi, Sara Abdollahi, Kaveh Ostad-Ali-AskariCement factories are found to be one of the major causes of pollution. Cement mist and dusts depositions affect the photosynthesis, secretion and fertility of the plant. Increasing the concentration of airborne dust reduces photosynthetic potential in leaves, closes leaf stomatals and, in general, reduces the growth and fertility of plants. The purpose of this study is to determine the … …American Journal of Engineering and Applied Sciences, Vol. 13, Issue 4 · 23 Nov 2020 · 6,438 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Euphorbia helioscopia Extract Administration on Diabetes Induced by Alloxan in MiceDoha Mohammad Beltagy, Amira Mohammed Beltagy, Mohammad Ramadan et al.Diabetes describes metabolic disorder with hyperglycemia and neurotic changes. This work aimed to evaluate the protective effect of total ethanolic extract of Euphorbia helioscopia grown in Egypt against pancreas and brain injuries in diabetic mice induced by alloxan. This work was carried out on 60 mice divided into four groups. Control Group (G1) included healthy normal mice that did not … …OnLine Journal of Biological Sciences, Vol. 20, Issue 3 · 19 Oct 2020 · 6,406 accessesView PDFCite
Research NotesOpen accessIn the abstractAn Artificial Design Technique to Optimize Signal PeptideGao Cui-Fang, Wang Sen, Tian Feng-Wei et al.To determine optimal artificial signal peptide candidates for the possibility of creating high levels of secretion of heterologous proteins, substitution and redesign of amino acid sequences in the H-domain of the signal peptide was theoretically attempted. The method was based on comprehensive score matrix and Markov transfer matrix, which can make the artificial sequences maintain the structural characteristics and original … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 3 · 21 Jul 2017 · 8,063 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of a Mushroom (Coriolus versicolor) Based Probiotic on Goat HealthKingsley Ekwemalor, Emmanuel Asiamah, Sarah Adjei-Fremah, Mulumebet WorkuMaintenance of an adequate immune response is essential to goat health. CorPet biomass is a mushroom (Coriolus versicolor) based probiotic used as an immune-stimulant in man, horses and small animals. Fifteen BoerXSpanish goats were used in a crossover design to evaluate the effect of a commercial mushroom based probiotic across two periods on resilience of goats to gastrointestinal parasites in … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 3 · 4 Oct 2016 · 7,923 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Effect of N-Acetylcystiene Against Titanium Dioxide Nanoparticles Modulated Immune Responses in Male Albino RatsMohamed Mohamed Soliman, Hossam Fouad Attia, Mohamed Mahmoud Hussein et al.The protective effects of N-Acetylcysteine (NAC) against orally administered titanium dioxide nanoparticles (TiO2) for 3 months on male albino rats were examined. Adult male albino rats were given saline as a control group, TiO2 (1200 mg kg-1 BW), NAC (100 mg kg-1 BW) and co-treatment of NAC and TiO2 as a protective group for 3 months. Blood was assayed for … …American Journal of Immunology, Vol. 9, Issue 4 · 30 Nov 2013 · 7,273 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Effects of Propolis on Gamma-Irradiated Nigella sativa Extract Induced Blood and Immune Changes in Wistar RatsOsama Moseilhy Saleh, Mohamed Mohamed Soliman, Ahmed Abdel-Khalik Mansour, Omniya Mahmoud Abdel-HamidThe present study conducted to test the effect of Nigella Sativa (NS, 5 mg kg-1 of body weight), or γ-irradiated Nigella Sativa (GRNS) on the changes of blood component profiles, liver, kidney functions and immune cytokines secretion in male Wistar rats. Moreover, the possible protection by propolis (200 mg kg-1 B. W.) on the changes induced by NS and GRNS … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 2 · 20 Jun 2013 · 7,463 accessesView PDFCite
Research ArticleOpen accessIn the abstractRegulation of Retinol Binding Protein 4 Expression and its Relation to Adipogenesis in Bovine AdipocytesMabrouk Ragab EL-Sabagh, Abd Eldaim Mabrouk AttiaAdipogenesis is of great importance in beef cattle. Recent findings indicate that glucose, a substrate for fatty acid biosynthesis and retinoic acid enhance adipogenesis in bovine intramuscular adipocytes. However, other recent findings indicate that Retinol-Binding Protein 4 (RBP4) interferes with glucose uptake and utilization by rodents’ adipocytes. In this study we examined the regulation of RBP4 expression and its relation … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 3 · 20 Sep 2012 · 8,399 accessesView PDFCite
Research ArticleOpen accessIn the abstractInfluence of Heirloom Tomato Polyphenol Extracts on Expression of Inflammation Genes in BovineKwaku Gyenai, Nona Mikiashvili, Hamid Ismail, Mulumebet WorkuThe effect of tomato on diseases of economic importance continues to be of broad interest. To evaluate these relationships, the effect of crude extracts of Cherokee purple tomato on pro-inflammatory genes and cytokines were evaluated. Neutrophils from three Holstein Fresian cows were treated with Phosphate Buffered Saline (PBS) or E. coli O111-B4 Lipopolysaccharide (LPS). Treated cells were exposed to different … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 3 · 25 Aug 2012 · 8,377 accessesView PDFCite