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Research ArticleOpen accessEvery word in the titleEffect of Cinnamomum cassia Stem-Bark Extracts on the Synthesis and Secretion of Insulin in RIN-m5F CellsAnanias Hodi Kgopa, Sebolaishi Doris Makhubela, Motetelo Alfred Mogale, Leshweni Jerry ShaiCinnamomum cassia (C. cassia) crude stem-bark extracts possess some hypoglycemic properties through inhibiting the uptake of glucose by the intestines and/or enhancing insulin sensitivity. To further investigate the mechanism through which the hypoglycemic effect is exerted, this research explored the influence of the extracts of the crude stem-bark of C. cassia, with various polarities, on particular aspects of glucose consumption … …OnLine Journal of Biological Sciences, Vol. 22, Issue 2 · 5 Apr 2022 · 5,784 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleBeyond Survival: The Unique Salt Secretion and Ion Homeostasis Mechanisms in Limonium bicolor Under Salt StressLinyang Wang, Pin Chen, Shuge TianSoil salinization poses a significant threat to global agriculture. Limonium bicolor, a recretohalophyte, has evolved a unique and efficient salt tolerance mechanism centered on epidermal salt glands for secreting excess salts. This review systematically synthesizes the multilevel salt tolerance strategies in Limonium bicolor, covering the structural basis of its multicellular salt glands, the molecular regulatory networks governing their development including … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 8 Sep 2026 · 791 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Effect of Gliflozin Therapy on TNF-α Secretion by Cultured Monocytes in Patients with DiabetesTatiana Vladimirovna Kirichenko, Leyla Azimovna Bochkareva et al.Currently it’s well established that chronic inflammation is a key pathogenetic mechanism in the development of Type 2 diabetes. The study aims to explore the inflammatory response of monocytes in diabetic patients compared to healthy subjects, focusing on TNF-α and to investigate the impact of SGLT2 inhibitors on monocyte inflammation. The study included 20 patients with newly diagnosed type 2 … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 15 Feb 2024 · 4,819 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAmphetamine Stimulates Protein Kinase and Calcium Influx to Increase Corticosterone and Aldosterone Secretion from Male Rat Adrenal CellsLing-Ling Chang, Wan-Song Alfred Wun, Cai-Yun Jian, Paulus S. WangAmphetamine is a potent central nervous system stimulant. Clinical trials have demonstrated that in healthy adults, low (therapeutic) doses of amphetamine can improve i.e., cognition, memory, attention behavior. An amphetamine overdose can affect cardiovascular, central nervous system, musculoskeletal, respiratory, urinary, or sexual function. Furthermore, amphetamine can activate the hypothalamic-pituitary-adrenal axis to increase glucocorticoids and mineralocorticoids released from adrenal. The object … …American Journal of Pharmacology and Toxicology, Vol. 16, Issue 1 · 10 Mar 2021 · 7,872 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMomordica balsamina Fruit Extracts Enhances Selected Aspects of the Insulin Synthesis/Secretion PathwayAnanias Hodi Kgopa, Leshweni Jerry Shai, Motetelo Alfred MogalePrevious studies have suggested that crude plant extracts of the anti-diabetic medicinal plant, Momordica balsamina (MB) may exert their anti-diabetic effect through either enhancement of insulin sensitivity or inhibition of intestinal glucose absorption. However, the effects of these MB extracts on insulin synthesis and secretion are not well documented in the literature. Therefore, a main purpose of the current research … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 4 · 17 Dec 2020 · 6,999 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAntifungal Activity of Skin Secretion of Bleeding Toad Leptophryne Cruentata and Javan Tree Frog Rhacophorus MargaritiferI. Made Artika, Sabrina Pinontoan, Mirza Dikari KusriniAmphibian skin has been the source of a wide variety of biologically active compounds. This study was aimed to determine antifungal activity of skin secretion of two species of anurans endemic in Indonesia, the bleeding toad Leptophryne cruentata and the javan tree frog Rhacophorus margaritifer. We collected 7 adults of L. cruentata and 10 adults of R. margaritifer from the … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 1 · 16 Jan 2015 · 8,127 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Fig (Ficus carica) Leaf Extract on the Secretion and Content of Cholesterol in Hepg2 CellAhmad Fatemi, Ali Rasouli, Farzad AsadiTraditional medicines remain a source of potential for discovering of new compounds with valuable pharmacological activities. Leaves of Ficus carica were dried, powdered and extracted using methanol (ME).An aliquot of ME was dried and re-extracted by water:chloroform and the other aliquot by water: peteruleum ether. Effect of aqueous fractions of the former (ACR; 0.08, 0.1 and 0.13 mg dL-1), the … …American Journal of Animal and Veterinary Sciences, Vol. 2, Issue 4 · 31 Dec 2007 · 7,420 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleControl of Phenolic Compound Secretion and Effect of Growth Regulators for Organ Formation from Musa spp. cv. Kanthali Floral Bud ExplantsSoubir Titov, Salil Kumar Bhowmik, Ajoy Mandal et al.The study was undertaken to examine banana cv. Kanthali floral bud apex as an alternative source material for in vitro propagation because huge number of explants die due to microbial contamination in case of shoot tip explants. Contamination free cultures were established by treating the floral bud explants with 0.1% HgCl2 for 6 min. This study found that inflorescence tissues … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 3 · 30 Sep 2006 · 7,742 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAntibacterial Activity of Skin Secretion of Bleeding Toad Leptophryne cruentata and Javan Tree Frog Rhacophorus margaritiferI Made Artika, Sabrina Pinontoan, Mirza Dikari KusriniBacterial resistance towards antibiotics has increased morbidity, mortality and health-care costs. Therefore, it is important to search for new types of antibacterial agents. This study was aimed to test antibacterial activity of epinephrine-stimulated skin secretions derived from two species of Anura endemic in Indonesia, the bleeding toad Leptophryne cruentata and the javan tree frog Rhacophorus margaritifer. The filter-sterilized skin secretions … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 3 · 7 Jul 2015 · 7,626 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Computer Simulation Model for Automated Quantification of Luteinizing Hormone SecretionAyman Al-Nsour, Hamza A. Ali, Buthynna Al-Dulaimi, Wisam H. Al-SewadiProblem statement: An automated software package is developed for quantifying Luteinizing Hormone (LH) release from pituitary gonadotropes in response to short pulses of Gonadotropin-Releasing Hormone (GnRH). Approach: These computer programs were designed to accommodate the release mechanism that consists of three stages, namely; (1) Production of different concentrations of effectors (such as receptor-hormone binds, G protein interactions, inositol 1,4,5-trisphosphate IP3), … …Journal of Computer Science, Vol. 5, Issue 6 · 30 Jun 2009 · 6,938 accessesView PDFCite