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82 results for “response surface method”
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Literature ReviewOpen accessIn the keywordsExtraction Performance of Essential Oils by Hydrodistillation Using Mathematical Models: A Systematic ReviewLenin Quiñones Huatangari, Frank Fernandez Rosillo, Eliana Milagros Cabrejos Barrios et al.Essential oils are complex mixtures of volatile organic compounds valued for their antimicrobial and antioxidant properties, with widespread applications in the food, pharmaceutical, and cosmetic industries. Among the various extraction techniques employed, hydrodistillation remains one of the most widely used methods. The extraction yield of essential oils by hydrodistillation is influenced by multiple factors, and quantifying these through mathematical modelling … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 25 Mar 2026 · 2,508 accessesView PDFCite
Research ArticleOpen accessIn the keywordsUltrasonic Microwave Assisted Extraction, Chemical Characterization and Antioxidant Activity of Polysaccharides from Fig LeavesBaikangzhe Zheng, Yang Miao, Yi Zhou et al.This study employed ultrasonic-microwave-assisted extraction (UMAE) to isolate water-soluble polysaccharides from fig (Ficus carica L.) leaves (FLPs). Polysaccharide yield was used as the primary index to evaluate extraction efficiency. The effects of material-liquid ratio, microwave power, extraction temperature, and extraction time on polysaccharide yield were systematically investigated through single-factor experiments, followed by response surface methodology optimization. Structural characterization and antioxidant … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 3 Mar 2026 · 1,671 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIsolation and Identification of Bacteria Leading to Microbial Spoilage of Sweet Potato and Screening for Antistaling Agents Running HeadDaoqi Liu, Huili Liu, Yuanyuan Dang et al.To develop natural preservatives tailored for sweet potatoes, the control effect of essential oils on the spoilage microorganisms of sweet potatoes is uncertain. Therefore, we first isolated and identified the dominant spoilage bacteria from spoiled sweet potatoes. Micrococcus aloeverae, Priestia aryabhattai, and Glutamicibacter arilaitensis were identified through screening, morphological observation, gram staining, and 16S rDNA assays. Subsequently, five plant essential … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 1 · 26 Apr 2024 · 5,221 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOptimization and Molecular Identification of Protease-Producing Thermophilic Bacterial Isolate TUA-26Anthoni Agustien, Mufidhatul Muqarramah, Feskaharny AlamsjahProtease enzymes are used as biocatalysts that can accelerate a reaction. Thermostable enzymes produced by thermophilic bacteria are needed in the industrial field because of their ability to withstand high temperatures. The thermophilic bacterial isolate TUA-26 that produces protease was to analyze the optimum conditions of temperature, pH, agitation, trace elements, carbon sources, and nitrogen sources; the stability of protease … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 6 Apr 2024 · 4,935 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOptimization of Preparation Procedures of Phlorizin-Zn (Ⅱ) Complex and Its Antioxidant Activity Study in vitroYuqing Zhang, Yaping Li, Guorui Yang et al.Flavonoid metal complexes possess more effective antioxidant properties than flavonoids. However, the preparation of the phlorizin-Zn (Ⅱ) complex and its antioxidant activity has not been reported. In this research, the preparation procedures of the phlorizin-Zn (Ⅱ) complex were enhanced using by single factor test and Response Surface Methodology (RSM). The optimal preparation procedures of the phlorizin-Zn (II) complex were as … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 3 Apr 2024 · 4,758 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSystematic Optimization of Ganoderma lucidum Polysaccharide Fermentation: A Guidance for IndustrializationBin Yang, Junhu Kai, Dehui Dai et al.Ganoderma Lucidum Polysaccharide (GLP) is one of the main active components of G. lucidum and a promising prebiotic for various diseases. Maximizing the production of GLP and minimizing the cost is important for the widespread use of GLP in the food/feed and pharmaceutical industries. The purpose of the present study was to optimize the fermentation condition of a single G. … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 30 Jan 2024 · 5,737 accessesView PDFCite
Research ArticleOpen accessIn the keywordsExtraction Process Optimization and Functional Characteristics of by Papain Solubilized Collagen from Large Yellow Croaker (Pseudosciaena crocea) SkinBiaoshi Wang, Wenfeng Li, Shumin Liu et al.Through collagen extraction from large yellow croaker (Pseudosciaena crocea) skin using an enzymatic method, the extraction optimization and characterization of collagen from raw materials after papain hydrolysis pretreatment are studied. The extraction process was optimized using the response surface methodology in this study. The findings show that the optimal conditions are a ratio (solvent to solid) of 25.0 mL/g, a … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 26 Dec 2023 · 5,553 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Efficiency of Seven-Variable Box-Behnken Experimental Design with Varying Center Runs on Full and Reduced Model TypesMary Paschal Iwundu, Joan CosmosResponse Surface Methodology is widely used in the optimization of industrial processes and products that depend on several experimental variables. One of the most tested and efficient second-order Response Surface Methodology designs is the Box-Behnken Design. This research explores the efficiency of a seven-variable Box-Behnken design with varying center runs, on full and reduced quadratic models. Backward Elimination and Forward … …Journal of Mathematics and Statistics, Vol. 18, Issue 1 · 8 Dec 2022 · 7,089 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPhytochemical Profiles and Anti-Diabetic Potential of the Extract of Pueraria lobata Compound Teabags: Preparation and Optimization Infusion ConditionsQing Liu, Wenyue Shi, Futing Xue et al.A Pueraria lobata root compound teabag using Pueraria lobate root, Stigma maydis, and Prunus mume as the main material was prepared in this study, and the brewing technology was optimized using Response Surface Methodology (RSM). The sensory evaluation, total polysaccharide, and phenolic compound content were used as evaluation indicators and the effect of the compound ratio of raw material was … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 26 Nov 2022 · 5,641 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHydroxyl Radical-Scavenging Activity-Guided Extraction of Peptides from Oviductus ranaeJieyang Shen, Yihui Liu, Jiahao Xu et al.Oviductus Ranae (OR) is a traditional Chinese medicinal material that is listed in Chinese Pharmacopeia with proteins the most abundant ingredients. In present work, pepsin/trypsin-based stepwise hydrolysis was applied to extract Antioxidant Peptides from OR (APOR) using hydroxyl radical-scavenging capacity as evaluation index. After single-factor experiment, response surface method coupled with Box-Behnken design were used for optimizing process parameters and … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 18 Oct 2021 · 6,609 accessesView PDFCite