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Research ArticleOpen accessIn the keywordsRelation between Macroscopic Binding Constant and the Anticancer Efficacy of the Bovine Serum Albumin-Quercetin Complex against Drug-Sensitive and Drug-Resistant CellsWinit Choiprasert, Chatchanok Loetchutinat, Nathupakorn Dechsupa, Samlee MankhetkornProblem statement: We have previously analyzed the interaction of BSA with flavonoids by using FRET. In this study, the role of BSA on increasing in solubility and on carrying the quercetin derivatives thus enhanced their anticancer efficacy against drug-sensitive and drug-resistant cells were conducted. Approach: The macroscopic (KD) and microscopic (kd) binding constant of the complexation and the cellular partition … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 1 · 27 May 2011 · 8,292 accessesView PDFCite
Research ArticleOpen accessIn the abstractAccumulation and Effect of Manganese on Chloroplasts and Antioxidant Responses in Arabidopsis ThalianaJun Xing, Xue Yang, Cailing YuanIn this study, 5-day-old seedlings of Arabidopsis thaliana were exposed to 0, 0.5, and 1.0 mmol/L MnCl₂ for 6 days by using three independent biological replicates. The results indicated that Mn content in roots exhibited a dose-dependent increase with rising external Mn supply. The elevated Mn levels led to significant reductions in the nutrient content of K, Ca, Na, and … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 18 Jul 2026 · 824 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Lead on the Chlorophyll and Antioxidant Response in the Leaves of Arabidopsis thalianaJun Xing, Cailing Yuan, Hui Yu et al.Lead (Pb) is a non-essential heavy metal element for plants. In this study, the effect of 0.025, 0.05, 0.1, 0.25, and 0.5 g/L Pb on the chlorophyll and antioxidant response was analyzed in the leaves of Arabidopsis thaliana. The results indicate that 0.025 g/L Pb had no significant effect on the fluorescence intensity of chlorophyll. However, 0.05, 0.1, 0.25, and … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 1 · 31 Mar 2024 · 4,628 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Trilobatin on Bovine Serum Albumin: Interaction Mechanism and Molecular DockingYuhan Zhai, Yuqing Zhang, Yaping Li et al.Understanding the transport and distribution of small molecules in vivo is aided by studying their interactions with proteins. As a natural sweetener, trilobatin possesses several biological activities. However, uncertainty surrounds the trilobatin and Bovine Serum Albumin (BSA) interaction mechanism. In this study, the binding types, number of binding sites and binding constants of trilobatin interaction with BSA were studied by … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 1 · 29 Mar 2024 · 4,843 accessesView PDFCite
Review ArticleOpen accessIn the abstractReview on Different Algorithms and Techniques Used in Classification of Gender in SilkwormJyoti Sharma, Pradeep ChoukseySilkworm seed is the key factor for the success of sericulture industry. Silk seed production process at grain ages centre mainly involve procuration of seed cocoon, cutting of seed cocoon for pupae, separation of male and female pupae, emergence of moth, coupling of silk moth and further egg laying by female moth. Separation of male and female is very much … …Journal of Computer Science, Vol. 21, Issue 6 · 17 Jun 2025 · 4,031 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Impact of XRF-Escape on Energy Resolution of NaI: Tl Scintillation Detectors for Medical Imaging or Gamma-Ray SpectroscopyRaffaele Scafè, Marco Puccini, Rosanna Pellegrini, Roberto PaniThe effect of escape of X-ray fluorescence from scintillator elemental components on the detector energy resolution is investigated from a spectroscopic standpoint, for monolithic and pixelated crystals. Along with these, any other emissions in a given region of interest were also considered. In present spectral evaluations a range of ratios between the areas of the peaks (XRFesc) to (XRFesc + … …American Journal of Applied Sciences, Vol. 21, Issue 1 · 10 Jul 2024 · 5,024 accessesView PDFCite
Research ArticleOpen accessIn the abstractEstablishment and Application of Rapid Quantitative Detection Technology for Bacillus cereusFeilong Sun, Hanyu Li, Jingxue Qian et al.Infections caused by Bacillus cereus often occur, causing a certain degree of health hazards and economic losses to people around the world. Rapid quantitative detection is of great significance for prevention. This study aims to develop a simple and rapid quantitative detection method for B. cereus, which can be used to monitor the contamination of B. cereus in food samples. … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 21 Mar 2023 · 5,564 accessesView PDFCite
Research ArticleOpen accessIn the abstractComplexation of Soy Protein Microgels and Isoflavones: Implication in Modulating BioavailabilityJuan Yang, Weifeng Lin, Xiaoquan Yang, Zhining BaoThe soy protein aggregate particles-isoflavones complexes (SPIGs) were prepared by thermally induced protein-polyphenol co-assembly and the in vitro bioavailability of isoflavones with different soy protein matrices was evaluated. The SPIG formed by heating SPI-isoflavone dispersion at 120°C in a narrow pH range, which was defined as spherical particles with uniform size, exhibited better colloidal stability and high isoflavone binding capacity, … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 10 Dec 2022 · 5,113 accessesView PDFCite
Short CommunicationsOpen accessIn the abstractCytotoxicity and Apoptosis-Induction Potential of Fraction F3 from Fruits of Bersama engleriana (Melanthaceae) against Human Cervical Cancer CellsMichèle Stella Majoumouo et al.Cervical cancer is one of the most life-threatening malignancies worldwide, despite intensive research for more efficacious chemotherapeutic agents. Recent efforts geared towards eradicating the scourge of cancer have embodied a major surge of interest in natural products as promising lead molecules in pharmaceutical development and therapeutic translation. Consequently, this study aimed to assess the cytotoxicity of a previously identified plant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 5 Dec 2022 · 5,292 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Anti-Inflammatory Potential of Turmimax® an in vivo and in vitro StudyFiroz Hussain H M., Nanjundaiah S., Sadashiva Channangihalli Thimmegowda et al.The main objective of this study was to investigate the in vivo and in vitro anti-inflammatory effects of the Turmimax® bio-enhanced turmeric formulation. By comparing the relative fluorescence intensities of the interleukins IL-8 (Interleukin-8) and IL-12 (Interleukin-12) cytokines in stimulated murine Raw 264.7 macrophages, Turmimax® was evaluated for its anti-inflammatory in vitro efficacy. Turmimax® was administered orally in two doses, … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 24 Nov 2022 · 6,581 accessesView PDFCite