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70 results for “SARS”
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Case ReportOpen accessIn the keywordsAcyclovir May Be Used to Treat Certain Long COVID Patients Regardless of Herpesvirus Reactivation: Case ReportDenise Stewart, Martin Oswald SavageFundamental causes of long COVID or Post-Acute Sequelae of COVID-19 (PASC) are still under investigation while it remains a significant burden to millions of patients worldwide even after a relatively mild acute Coronavirus Disease 2019 (COVID-19) episode. Treatment and management programs are yet to be developed. The foremost hypotheses for underlying PASC pathophysiology include: The persistence of the virus in … …American Journal of Infectious Diseases, Vol. 20, Issue 1 · 12 Mar 2024 · 25,572 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRelease of Endogenous Chondroitin Sulfate and Heparin as Consequence of Dysregulated Proteolysis in COVID-19Marco RuggieroInfection by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), the pathogen responsible for COVID-19, is associated with immune-mediated responses that lead to dysregulated activation of proteolytic enzymes; these contribute to damage to the endothelium, thrombosis, hypercoagulability and other hematologic complications that include thrombotic thrombocytopenia, a complication of severe COVID-19 as well as a potentially fatal adverse effect of COVID-19 vaccination. … …American Journal of Immunology, Vol. 17, Issue 1 · 29 Dec 2021 · 7,688 accessesView PDFCite
Review ArticleOpen accessIn the keywordsCOVID-19: A Review of Current Evidence on Phylogenetics and EtiopathogenesisRafiq Shajahan, Naganathan K. PillaiCOVID-19 represents the latest pandemic caused by the SARS-CoV-2 coronavirus. Coronaviruses are RNA viruses that cause a largely viral mediated immune-related syndrome similar to the SARS epidemic. Following metagenomic sequencing, SARS-CoV-2 closely resembles SARS-CoV (79% similarity) and MERS-CoV virus (50% similarity). Despite this, clinical observations have found varying degrees of infectivity and pathogenesis amongst these viruses. Phylogenetic origins of SARS-CoV-2 … …American Journal of Infectious Diseases, Vol. 17, Issue 1 · 2 Apr 2021 · 6,764 accessesView PDFCite
Literature ReviewOpen accessIn the keywordsPotential Pathomechanism of Neuro-COVID-19Abir Fguirouche, Nissrine Louhab, Mohamed Chraa et al.Gathered data about SARS-CoV-2 have shown strong evidence in terms of neuroinvasive and neurotropic capacities of the virus to reach and cause eventual damage to the Central Nervous System. The spread of the virus may occur through direct and indirect ways, leading to anosmia and/or ageusia. These signs have been observed in many COVID-19 patients and are then included in … …OnLine Journal of Biological Sciences, Vol. 20, Issue 4 · 7 Dec 2020 · 6,542 accessesView PDFCite
Research ArticleOpen accessIn the keywordsStochastic and Deterministic Mathematical Modeling and Simulation to Evaluate the Novel COVID-19 Pandemic Control MeasuresEva Gupta, Nand Jee Kanu, Amartya Munot et al.Background: In India, the novel Coronavirus Disease (COVID-19) epidemic has grown to 17,00000 cases and around 38,000 deaths up to 30th July, 2020. The impacts of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic in India were studied using modified age-structured stochastic and deterministic mathematical models. Methods: A compartmental susceptible (S)-infected (symptomatic) (IS) infected (asymptomatic) (IN) recovered (R) i.e., … …American Journal of Infectious Diseases, Vol. 16, Issue 4 · 20 Nov 2020 · 8,456 accessesView PDFCite
Review ArticleOpen accessIn the keywordsAn Insight into the Simplified RP Transmission Network, Concise Baseline and SIR Models for Simulating the Transmissibility of the Novel Coronavirus Disease 2019 (COVID-19) OutbreakEva Gupta, Nand Jee KanuThe World Health Organization has reported about a Severe Acute Respiratory Syndrome, Coronavirus 2 (SARS-CoV2) (a virus of Wuhan, China pneumonia). The present investigation explores the transmissibility of the novel Coronavirus Disease (COVID-19) using some suitable mathematical models such as (a) a simplified Bats-Hosts-Reservoir (Wuhan Seafood Market)-People (BHRP) transmission network model useful in mapping the spread of the novel COVID-19 … …American Journal of Infectious Diseases, Vol. 16, Issue 2 · 1 Jul 2020 · 7,586 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHow Prepared are we to Control Severe Acute Respiratory Syndrome in FutureKanchan BhardwajNo non-human reservoirs for smallpox- and polio-viruses has contributed to the success of worldwide eradication of smallpox and a significant control of poliomyelitis. Most emerging and re-emerging viruses including SARS Coronavirus (SARS-CoV), have animal reservoirs and therefore,they impose a constant threat of host jump leading tooutbreaksin humans. It is desirable to be ready for control of infections that are caused … …Current Research in Virology, Vol. 2, Issue 1 · 29 Jul 2013 · 9,070 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRapid Recovery of Peripheral Oxygen Saturation in Hypoxic COVID-19 Patients With Ivermectin/Doxycycline/Zinc Multidrug TherapySabine Hazan, Adriana C. Vidal, Eleftherios Gkioulekas et al.Several combination therapies for the early outpatient treatment of COVID-19 were proposed by independent research groups at the onset of the pandemic during 2020 and 2021. In this observational study, we report on the outcomes of an off-label triple combination therapy, consisting of ivermectin, doxycycline, and zinc, with adjunct vitamin C and D3 supplementation, which was used on high-risk COVID-19 … …American Journal of Infectious Diseases, Vol. 22, Issue 1 · 3 Jul 2026 · 3,374 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBacterial Resistance in Primary Bloodstream Infections in the COVID-19 Pandemic: What has Changed at a Reference Hospital in Northeastern Brazil?Jonathan Da Silva Xavier, Jorge Luiz Nobre Rodrigues, Caroline Mary Gurgel Dias Florêncio et al.The increased use of central venous catheters due to the severity of COVID-19 cases and the difficulty in implementing preventive Healthcare-Associated Infection measures contributed to worsening an already challenging scenario of bacterial resistance. Characterizing the impact of these significant health crises on the bacterial resistance profile is necessary to strengthen antimicrobial control protocols in an effort to decrease morbidity. Our … …American Journal of Infectious Diseases, Vol. 20, Issue 2 · 4 Sep 2024 · 5,033 accessesView PDFCite