30 articles for “Genomic DNA”

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Research ArticleOpen accessIn the abstractMicrornas as Double Edged Sword in CancerBaby Joseph, Vrundha M. NairCancer is the leading causes of death world wide. Basically it can be defined as the disease of the cell. One among the mechanism of transfer of a normal cell to cancerous is the alteration in the genetic material DNA. Treatment for cancer remains as a biggest challenge. Here comes the importance of miRNAs. They are endogenous RNA which regulates … …Current Research in Bioinformatics, Vol. 2, Issue 1 · 24 May 2013 · 6,953 accessesView PDF Cite

Research ArticleOpen accessIn the abstractG-2548A Leptin Promoter and Q223R Leptin Receptor Polymorphisms in Obese Mexican SubjectsP. Carrillo-Vazquez Jonathan, Lopez-Alcantar Jeronimo, Chimal-Vega Brenda et al.Leptin interaction with its receptor in the hypothalamus stimulates a specific signaling cascade that results in the synthesis of anorexigenic and orexigenic peptides in order to regulate food intake and energy expenditure. Many polymorphisms in leptin (lep) and leptin receptor (lepr) genes have been associated with body weight. In particular, G-2548A in the lep promoter and Q223R in lepr variants … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 1 · 12 Feb 2013 · 8,641 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDetection of Polymorphism at the Insulin Like Growth Factor-I Gene in Mazandaran Native Chicken using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism MethodHossein Ali Abbasi, Mohsen KazemiProblem statement: Molecular genetics selection on individual genes is a promising method to genetically improve economically important traits in chickens. The Insulin like Growth Factor-I (IGF1) gene may play important roles in growth of multiple tissues, including muscle cells, cartilage and bone. Approach: In the present study polymorphism of the promoter and 5' untranslated region of IGF-1 gene of Mazandaran … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 2 · 8 Aug 2011 · 7,627 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDesign and Evaluation of Three Pair Primers for Exon 1 Amplification of Hyaluroglucosaminidase-1 GeneUsman Sumo Friend Tambunan, Sylvia Sugito, Arli Aditya ParikesitProblem statement: Hyaluronidase is an enzyme which catalyze hydrolysis of Hyaluronan (HA). Hyaluronan is important in cell migration during embryonic development, cellular proliferation and differentiation and has a structural role in connective tissues. Hyaluronidase deficiency is correlated with mucopolysaccharidosis IX. In human, hyaluronidase is encoded by HYAL1 gene. The mutation study of HYAL1 gene was carried out by many researchers, … …OnLine Journal of Biological Sciences, Vol. 10, Issue 2 · 16 Jun 2010 · 8,702 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Porcine Mitochondrial Transcription Factor a Gene: Molecular Characterization, Radiation Hybrid Mapping and Genetic Diversity among 12 Pig BreedsTanja Kunej, Xiao-Lin Wu, Jennifer J. Michal et al.Problem statement: Mitochondrial transcription factor A (TFAM) is a nucleus-encoded protein that is a key activator of mitochondrial transcription as well as a major participant in mitochondrial genome replication. Genomic characterization of the porcine TFAM gene is, therefore, necessary to determine its involvement in regulation of fat depots and meat quality traits in pigs. Approach: Genomic DNA sequence was determined … …American Journal of Animal and Veterinary Sciences, Vol. 4, Issue 4 · 31 Dec 2009 · 6,870 accessesView PDF Cite

Research ArticleOpen accessIn the abstractGenetic Diversity Analysis of the Gohilwari Breed of Indian Goat (Capra hircus) Using Microsatellite MarkersSubodh Kumar, S. P. Dixit, N. K. Verma et al.Problem statement: Gohilwari breed of goat is a multipurpose goat mainly for milk and meat purposes and best suited in its harsh climatic condition. This breed is inadequately characterized till now at DNA level. So the present study was undertaken for population genetic analysis at molecular level to exploit the breed for planning sustainable improvement, conservation and utilization, which subsequently … …American Journal of Animal and Veterinary Sciences, Vol. 4, Issue 3 · 30 Sep 2009 · 8,925 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMolecular Characterization of Opium Poppy (Papaver somniferum) GermplasmHari Shanker Acharya, Vimal SharmaProblem statement: The medicinal value of opium poppy (2n = 22, Papaver somniferum L.) is due to presence of more than two dozen alkaloids. The genetic origin and diversity of cultivars used in the breeding collection is not fully known. To evaluate the genetic diversity of the 24 germplasm currently cultivated in the state to provide genetic information about heterogeneity, … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 8,096 accessesView PDF Cite

Research ArticleOpen accessIn the abstractLack of Association of Glutathione S-transferase Gene Polymorphisms in Iranian Prostate Cancer SubjectsB. Sahar Ansari, R. Vasudevan, M. Mirinargesi et al.Problem statement: Glutathione S-transferase is super family genes that encode enzymes which involve in the detoxification of the cell and protects DNA from damage. Conflicting results was found in several studies in association with GSTT1 and GSTM1 gene polymorphisms and prostate cancer. In this study, we determined the association between the GSTT1 and GSTM1 gene polymorphism and prostate cancer in … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 1 · 31 Mar 2009 · 8,273 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIsolation and Characterization of Thermophilic Cellulase-Producing Bacteria from Empty Fruit Bunches-Palm Oil Mill Effluent CompostAzhari Samsu Baharuddin, Mohamad Nafis Abd Razak, Lim Siong Hock et al.Problems statement: Lack of information on locally isolated cellulase-producing bacterium in thermophilic compost using a mixture of Empty Fruit Bunch (EFB) and Palm Oil Mill Effluent (POME) as composting materials. Approach: The isolation of microbes from compost heap was conducted at day 7 of composting process where the mixture of composting materials consisted of 45.8% cellulose, 17.1% hemicellulose and 28.3% … …American Journal of Applied Sciences, Vol. 7, Issue 1 · 31 Jan 2010 · 12,155 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordAlcohol Intubation and Synergistic Effect of Folic Acid and Egg Yolk Powder Solution on Alcohol Dehydrogenase [ADH] Class I Gene Expression and Single Nucleotide Polymorphism Frequency in Parent and Prenatal Alcohol Exposed Wistar RatsAdejoke Olukayode Obajuluwa, Oluyinka Ajibola Iyiola, Joseph Akintade Morakinyo et al.Point mutation detections in alcohol metabolizing genes could unravel molecular targets of gestational alcohol and epigenetic remodeling capacity of maternal nutrition, which underscores growth and health endpoints in Prenatal Alcohol Exposed (PAE) fetuses. gene expression was assayed using sequenced target and internal control gene primers in a two-step thermal cycling process from isolated RNA in purely bred alcohol male and … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 22 Nov 2023 · 4,857 accessesView PDF Cite