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77 results for “Disease Progression”
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Research ArticleOpen accessIn the abstractMMP-9 is a Potential Prognostic Marker of Left Ventricular Remodeling in Patients with Coronary Artery DiseaseMikhail Aleksandrovich Popov, Anastasia Vladimirovna Poznyak, Dmitry Valerievich Shumakov et al.Matrix Metalloproteinase-9 (MMP-9) emerges as a promising prognostic marker for assessing left ventricular remodeling in patients with coronary artery disease, particularly in the context of Ischemic Heart Disease (IHD) complicated by left ventricular aneurysm. In this study, we conducted two parallel investigations to explore the prognostic significance of MMP-9 in patients with multivessel coronary artery disease undergoing left ventricular reconstruction … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 11 Jul 2024 · 4,310 accessesView PDFCite
Review ArticleOpen accessIn the abstractOverview of Vascular Smooth Muscle Cells, Endothelial Cells, and Macrophages Apoptosis During Atherosclerosis DevelopmentAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Atherosclerosis is a complex disease that has garnered significant attention from researchers studying its various aspects. Its pathogenesis involves a wide array of cellular and molecular components, as well as crucial mechanisms and processes crucial for cellular and organismal functioning. Atherosclerosis is considered a chronic inflammatory disease characterized by disrupted lipid metabolism, oxidative stress, and immune response. Apoptosis, a fundamental … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 5 Jul 2024 · 4,675 accessesView PDFCite
Review ArticleOpen accessIn the abstractSIRT1 Controls Lipid Metabolism Under Physiological and Pathological Conditions: Implications in AtherosclerosisAnastasia Vladimirovna Poznyak, Ludmila Viktorovna Nedosugova, Victoria Alexandrovna Khotina et al.This comprehensive review examines the multifaceted role of Sirtuin 1 (SIRT1) in cellular metabolism and energy regulation, with a particular focus on its involvement in lipid metabolism and glucose regulation. Additionally, SIRT1's impact on several pathologies, including osteoarthritis, diabetes, and cardiovascular disease, is explored. Notably, this review sheds light on the unique contribution of SIRT1 in the development and progression … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 7 Jun 2024 · 4,739 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Review ArticleOpen accessIn the abstractLong Way of Evaluating Niacin for Atherosclerosis TreatmentAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Elizaveta Mikhailovna Pleshko et al.Atherosclerosis is a significant public health challenge, as it is closely associated with a wide range of cardiovascular diseases and complications. Despite its grave implications, the timely detection and treatment of atherosclerosis remain complex tasks due to the intricate pathogenesis involved, which encompasses numerous processes and mechanisms. Extensive research has been conducted to investigate various therapeutic methods and drugs aimed … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 24 Feb 2024 · 5,122 accessesView PDFCite
Review ArticleOpen accessIn the abstractFemale Sex Hormones Contribute to Vulnerability to Athero-Sclerosis: Overview of Mechanisms and Specific Risk FactorsAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Alexandra Alexandrovna Melnichenko et al.Atherosclerosis poses a significant challenge to the general population, with its prevalence particularly prominent among older individuals. Age, however, is not the sole determinant of risk, as gender also plays a crucial role. Sex-related disparities exist not only in the incidence of atherosclerosis but also in its progression and development. The intricate interplay of hormones in the female reproductive system … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 11 Jan 2024 · 4,633 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Integrated Machine Learning Model for Heart Disease Classification and CategorizationSrikanth Meda, Raveendrababu BhogapathiProgressions in the coordination among the machine learning algorithms, helped to achieve high accuracy and reliability in decision-making systems. Due to the impact and importance of heart diseases in real life, designing the efficient heart disease prediction model become a pivotal aspect today. Former research scholars applied the popular supervised machine learning models like Decision Trees, Naïve Bayes, ANN's, and … …Journal of Computer Science, Vol. 18, Issue 4 · 19 Apr 2022 · 6,535 accessesView PDFCite
Review ArticleOpen accessIn the abstractA Review of Technological Progression from Radiomics to Breathomics for Early Detection of Lung CancerFunmilayo S. Moninuola, Oluwadamilola Oshin, Emmanuel Adetiba et al.Lung Cancer (LC) is formed by an uncontrolled growth of abnormal cells in the lungs, which alters the body's metabolism. Early detection of LC is very important for a better survival rate and prognosis in patients and persons at risk of the disease. Traditional approaches to LC detection are less sensitive to cancerous cells at the early stage, are invasive … …Journal of Computer Science, Vol. 17, Issue 11 · 26 Nov 2021 · 6,257 accessesView PDFCite
Case ReportOpen accessIn the abstractCOVID-19 Diagnosis in Asymptomatic: RT-qPCR or any other Cost-Effective Method?Mayank Agarwal, Yogesh Arvind Bahurupi, Prasan Kumar PandaOn January 30th, 2020, the World Health Organization announced the COVID-19 outbreak as a Public Health Emergency of International Concern. In the view of this pandemic, early diagnosis is the mainstay for halting the disease progression. Quantitative real-time Reverse Transcriptase-Polymerase Chain Reaction (RT-qPCR) has been established as the cornerstone for the diagnosis of COVID-19. However, the significance of RT-qPCR positivity … …American Journal of Infectious Diseases, Vol. 17, Issue 3 · 2 Jun 2021 · 6,557 accessesView PDFCite
Case ReportOpen accessIn the abstractA Unique Presentation of Creutzfeldt-Jakob Disease in a Patient Consuming Deer Antler VelvetJoseph Wiedemer, Yanely Sanchez Ceja, An Cao, Ibrahim MustafaCreutzfeldt-Jakob Disease (CJD) is a rare rapidly progressive neurodegenerative prion disorder that is usually sporadic but may also be acquired from exposure to infected sources, classically via infections of bovine or human etiology. Cervid transmission of CJD is of particular concern in North America given the rapid spread of Chronic Wasting Disease (CWD)- the Cervid version of CJD. We present … …American Journal of Infectious Diseases, Vol. 17, Issue 1 · 18 Mar 2021 · 7,551 accessesView PDFCite