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Research ArticleOpen accessEvery word in the titleBioassay Guided Isolation of Antibacterial Compounds from Andrographis paniculataAbubakar Sule, Qamar Uddin Ahmed, Othman Abd. Samah et al.Problem statement: Chronic disease-causing bacteria of medical importance have developed resistance to antibiotics, hence, necessitating distinct and constant need for safe and efficient therapeutic agents. Plants are considered potent candidate for this aim. A way out of reducing antibiotic resistance and adverse effects on host is the employment of antibiotic resistance inhibitors of plant origin. Approach: About 5 kg pulverized … …American Journal of Applied Sciences, Vol. 8, Issue 6 · 13 Jun 2011 · 10,025 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSynthesis, Characterization and Biological Activities of Organotin (IV) Methylcyclohexyldithiocarbamate CompoundsNormah Awang, Ibrahim Baba, Bohari M. Yamin et al.Problem statement: The growing interest in the chemistry of sulphur donor ligands are due to their encouraging anticancer, antibacterial and antifungal activities as well as their widespread industrial application. Dithiocarbamates belong to this class and much attention has been paid to them. Approach: Novel organotin compounds with the molecular formula RmSn[S2CN(CH3)(C6H11)]4-m (where m = 2, R = CH3, C2H5; m … …American Journal of Applied Sciences, Vol. 8, Issue 4 · 18 Apr 2011 · 9,210 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleGermination Time Dependence of Bioactive Compounds and Antioxidant Activity in Germinated Rough Rice (Oryza sativa L.)Anuchita Moongngarm, Ekkalak KhomphiphatkulProblem statement: Germinated rice has been recognized as a functional food and its health benefits. However, most related studies were on germinated brown rice but our previous study indicated that germination of rough rice was an effective method to obtain high concentrations of bioactive compounds. Germination time is one of the most important factors affecting the level of biochemical compositions … …American Journal of Applied Sciences, Vol. 8, Issue 1 · 31 Jan 2011 · 8,663 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCyclic Volta Metric Study of Alizarin Yellow R and Some Analogous Arylazo Compounds in DMF and in Aqueous MediaHossnia MohranThe Cyclic Voltammetry (CV) was used to investigate the electrochemical behavior of alizarin yellow R and some analogous arylazo compounds having almost the same central azo group. For this purpose, the substances chosen for the measurements are Alizarin Yellow R (AYR), Eriochrome Black T (EBT) and Sudan II (SUD II). The investigations were carried out at room temperature (298 K) … …American Journal of Applied Sciences, Vol. 2, Issue 12 · 31 Dec 2005 · 7,235 accessesView PDFCite
HypothesisOpen accessEvery word in the titleCJ-023,423 (Grapiprant) a Potential Novel Active Compound with Antihyperalgetic Properties for Veterinary PatientsMario GiorgiCompanion animals are now living longer and so are more commonly manifesting age- and pain-related disease. Nonsteroidal anti-inflammatory drugs are the most used drug in osteoarthritis and inflammatory pain of various aetiologies. Despite their safety profiles have been amended from the COX-non selective to the COX-2 selective inhibitor class, some adverse effects are still of concern especially in long term … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 14 May 2015 · 8,874 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleFirst Token Algorithm for Searching Compound Terms Using Thesaurus DatabaseYousef Abuzir, Thabit SabbahProblem statement: Searching text materials is the one of the most important operations that carried out by search engines either on web or desktop applications, searching algorithms are required sometimes to find a specific word into a text, others to find a multi word term (pattern matching) into a text. Searching for term into a thesaurus database can be carried … …Journal of Computer Science, Vol. 8, Issue 1 · 28 Oct 2011 · 7,946 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMathematical Approach to the Ruin Problem with Compounding AssetsMercy Amaebi OrukariThis study considered the Ruin problem with an income process with stationary independent increments. The characterization is obtained which is general for the probability of $r(y)$, that the asset of a firm will never be zero whenever the initial asset level of the firm is $y$. The aim of this study is also to determine $r(y) = P \{ T … …Journal of Mathematics and Statistics, Vol. 18, Issue 1 · 8 Oct 2022 · 5,627 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleUse of Novel Triphenyltin (IV) Dithiocarbamate Compounds in Assessing the Cytotoxicity and Mode of Cell Death of Acute Lymphoblastic Leukemia Cell Lines, CCRF CEM (CCL-119)Normah Awang, Nur Hidayah Hasrin, Nurul Farahana Kamaludin et al.Chemotherapy and radiotherapy are often used to treat Acute Lymphoblastic Leukemia (ALL). However, the resistance problem of treatment using the current drug in ALL patients has decreased the effectiveness of such therapy. Therefore, a study needs to be conducted to identify the potential of new anticancer agents. Organotin (IV) dithiocarbamate, an organometallic compound, causes toxic effects on cancer cells in … …OnLine Journal of Biological Sciences, Vol. 23, Issue 2 · 10 Mar 2023 · 5,159 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePhytochemical Profiles and Anti-Diabetic Potential of the Extract of Pueraria lobata Compound Teabags: Preparation and Optimization Infusion ConditionsQing Liu, Wenyue Shi, Futing Xue et al.A Pueraria lobata root compound teabag using Pueraria lobate root, Stigma maydis, and Prunus mume as the main material was prepared in this study, and the brewing technology was optimized using Response Surface Methodology (RSM). The sensory evaluation, total polysaccharide, and phenolic compound content were used as evaluation indicators and the effect of the compound ratio of raw material was … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 26 Nov 2022 · 5,641 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleVirtual Screening of Bioactive Compounds from the Onion (Allium) Genus as Potential Epidermal Growth Factor Receptor Inhibitors for MonkeypoxDinda Ratu Agustiani, Rakhmat Ramdhani Alwie, Harry NoviardiMonkeypox (Mpox) is an emerging zoonotic disease caused by the Mpox virus infection that affects humans and animals. Epidermal Growth Factor Receptor (EGFR) is an important target in the pathogenesis of Mpox. Epidermal Growth Factor (EGF), encoded by orthopoxviruses, plays an important role in intercellular transmission of the virus. Onion is known to have antiviral and immunomodulatory properties. Active compounds … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 6 Aug 2026 · 945 accessesView PDFCite